6I2Z
| Isolated globin domain of the Bordetella pertussis globin-coupled sensor | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Uncharacterized protein | 著者 | Germani, F, De Schutter, A, Cuypers, B, Berghmans, H, Van Hauwaert, M.-L, Bruno, S, Mozzarelli, A, Moens, L, Van Doorslaer, S, Bolognesi, M, Pesce, A, Dewilde, S. | 登録日 | 2018-11-02 | 公開日 | 2019-10-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural and Functional Characterization of the Globin-Coupled Sensors ofAzotobacter vinelandiiandBordetella pertussis. Antioxid.Redox Signal., 32, 2020
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6I6I
| Circular permutant of ribosomal protein S6, adding 6aa to C terminal of P68-69, L75A mutant | 分子名称: | 30S ribosomal protein S6,30S ribosomal protein S6, SULFATE ION | 著者 | Wang, H, Logan, D.T, Oliveberg, M. | 登録日 | 2018-11-15 | 公開日 | 2019-11-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
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3ZCT
| Rabbit muscle glycogen phosphorylase b in complex with N-(2-naphthoyl) -N-beta-D-glucopyranosyl urea determined at 2.0 A resolution | 分子名称: | GLYCOGEN PHOSPHORYLASE, MUSCLE FORM, INOSINIC ACID, ... | 著者 | Chrysina, E.D, Nagy, V, Felfoldi, N, Konya, B, Telepo, K, Praly, J.P, Docsa, T, Gergely, P, Alexacou, K.M, Hayes, J.M, Konstantakaki, M, Kardakaris, R, Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G, Somsak, L. | 登録日 | 2012-11-21 | 公開日 | 2013-12-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Synthesis, Kinetic, Computational and Crystallographic Evaluation of N-Acyl-N-Beta-D- Glucopyranosyl)Ureas, Nanomolar Glucose Analogue Inhibitors of Glycogen Phosphorylase, Potential Antidiabetic Agents To be Published
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6I1M
| Secreted type 1 cystatin from Fasciola hepatica | 分子名称: | Cystatin, IODIDE ION | 著者 | Busa, M, Rezacova, P, Pachl, P, Stefanic, S, Mares, M. | 登録日 | 2018-10-29 | 公開日 | 2020-08-26 | 最終更新日 | 2023-03-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | An evolutionary molecular adaptation of an unusual stefin from the liver fluke Fasciola hepatica redefines the cystatin superfamily. J.Biol.Chem., 299, 2023
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6I6S
| Circular permutant of ribosomal protein S6, adding 9aa to C terminal of P68-69, L75A mutant | 分子名称: | 30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6,30S ribosomal protein S6, POTASSIUM ION, SODIUM ION | 著者 | Wang, H, Logan, D.T, Oliveberg, M. | 登録日 | 2018-11-15 | 公開日 | 2019-11-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
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3OEI
| Crystal structure of Mycobacterium tuberculosis RelJK (Rv3357-Rv3358-RelBE3) | 分子名称: | CITRATE ANION, RelJ (Antitoxin Rv3357), RelK (Toxin Rv3358) | 著者 | Miallau, L, Cascio, D, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2010-08-12 | 公開日 | 2011-03-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.145 Å) | 主引用文献 | Comparative proteomics identifies the cell-associated lethality of M. tuberculosis RelBE-like toxin-antitoxin complexes. Structure, 21, 2013
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6J9M
| NmeBH+AcrIIC2 | 分子名称: | AcrIIC2, CRISPR-associated endonuclease Cas9 | 著者 | Zhu, Y.L, Gao, A, Serganov, A, Gao, P. | 登録日 | 2019-01-23 | 公開日 | 2019-03-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.394 Å) | 主引用文献 | Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins. Mol. Cell, 74, 2019
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4BWJ
| KlenTaq mutant in complex with DNA and ddCTP | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*CP)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*DOCP)-3', ... | 著者 | Blatter, N, Bergen, K, Welte, W, Diederichs, K, Marx, A. | 登録日 | 2013-07-03 | 公開日 | 2013-09-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure and Function of an RNA-Reading Thermostable DNA Polymerase. Angew.Chem.Int.Ed.Engl., 52, 2013
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1SME
| PLASMEPSIN II, A HEMOGLOBIN-DEGRADING ENZYME FROM PLASMODIUM FALCIPARUM, IN COMPLEX WITH PEPSTATIN A | 分子名称: | PLASMEPSIN II, Pepstatin | 著者 | Silva, A.M, Lee, A.Y, Gulnik, S.V, Goldberg, D.E, Erickson, J.W. | 登録日 | 1996-06-11 | 公開日 | 1997-01-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum. Proc.Natl.Acad.Sci.USA, 93, 1996
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6OMU
| Structure of human Bruton's Tyrosine Kinase in complex with Evobrutinib | 分子名称: | 1-[4-({[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino}methyl)piperidin-1-yl]prop-2-en-1-one, CHLORIDE ION, Tyrosine-protein kinase BTK | 著者 | Mochalkin, I, Gardberg, A.S. | 登録日 | 2019-04-19 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases. J.Med.Chem., 62, 2019
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3VWB
| Crystal structure of VirB core domain (Se-Met derivative) complexed with the cis-acting site (5-BRU modifications) upstream icsb promoter | 分子名称: | DNA (26-MER), Virulence regulon transcriptional activator virB | 著者 | Gao, X.P, Waltersperger, S, Wang, M.T, Cui, S. | 登録日 | 2012-08-21 | 公開日 | 2013-08-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.416 Å) | 主引用文献 | Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes Nucleic Acids Res., 41, 2013
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1S7Z
| Structure of Ocr from Bacteriophage T7 | 分子名称: | CESIUM ION, Gene 0.3 protein | 著者 | Walkinshaw, M.D, Taylor, P, Sturrock, S.S, Atanasiu, C, Berg, T, Henderson, R.M, Edwardson, J.M, Dryden, D.T. | 登録日 | 2004-01-30 | 公開日 | 2004-02-10 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Structure of Ocr from Bacteriophage T7, a Protein that Mimics B-Form DNA Mol.Cell, 9, 2002
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6EHD
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1SKS
| Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template | 分子名称: | 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*C*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3', DNA polymerase, ... | 著者 | Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T. | 登録日 | 2004-03-05 | 公開日 | 2004-07-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Nat.Struct.Mol.Biol., 11, 2004
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6EID
| Crystal structure of wild-type Channelrhodopsin 2 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Archaeal-type opsin 2, PHOSPHATE ION, ... | 著者 | Borshchevskiy, V, Kovalev, K, Volkov, O, Polovinkin, V, Marin, E, Balandin, T, Astashkin, R, Bamann, C, Bueldt, G, Willlbold, D, Popov, A, Bamberg, E, Gordeliy, V. | 登録日 | 2017-09-19 | 公開日 | 2017-12-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structural insights into ion conduction by channelrhodopsin 2. Science, 358, 2017
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1SN5
| Crystal Structure of Sea Bream Transthyretin in complex with Triiodothyronine at 1.90A Resolution | 分子名称: | 3,5,3'TRIIODOTHYRONINE, SULFATE ION, transthyretin | 著者 | Eneqvist, T, Lundberg, E, Karlsson, A, Huang, S, Cantos, C.R, Power, D.M, Sauer-Eriksson, A.E. | 登録日 | 2004-03-10 | 公開日 | 2004-08-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | High resolution crystal structures of piscine transthyretin reveal different binding modes for triiodothyronine and thyroxine. J.Biol.Chem., 279, 2004
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3M66
| Crystal structure of human Mitochondrial Transcription Termination Factor 3 | 分子名称: | mTERF domain-containing protein 1, mitochondrial | 著者 | Spahr, H, Samuelsson, T, Hallberg, B.M, Gustafsson, C.M. | 登録日 | 2010-03-15 | 公開日 | 2010-05-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of mitochondrial transcription termination factor 3 reveals a novel nucleic acid-binding domain. Biochem.Biophys.Res.Commun., 397, 2010
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6ENE
| OmpF orthologue from Enterobacter cloacae (OmpE35) | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Outer membrane protein (Porin), SULFATE ION, ... | 著者 | van den Berg, B, Abellon-Ruiz, J, Basle, A. | 登録日 | 2017-10-04 | 公開日 | 2018-10-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Getting Drugs into Gram-Negative Bacteria: Rational Rules for Permeation through General Porins. Acs Infect Dis., 4, 2018
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1SFO
| RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX | 分子名称: | DNA STRAND, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ... | 著者 | Westover, K.D, Bushnell, D.A, Kornberg, R.D. | 登録日 | 2004-02-20 | 公開日 | 2004-03-02 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.61 Å) | 主引用文献 | Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II Science, 303, 2004
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6E58
| Crystal structure of Streptococcus pyogenes endo-beta-N-acetylglucosaminidase (EndoS2) | 分子名称: | CALCIUM ION, Secreted Endo-beta-N-acetylglucosaminidase (EndoS) | 著者 | Klontz, E.H, Trastoy, B, Gunther, S, Guerin, M.E, Sundberg, E.J. | 登録日 | 2018-07-19 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Molecular Basis of Broad SpectrumN-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2. ACS Cent Sci, 5, 2019
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1SL6
| Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x. | 分子名称: | C-type lectin DC-SIGNR, CALCIUM ION, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose | 著者 | Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K. | 登録日 | 2004-03-05 | 公開日 | 2004-06-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural basis for distinct ligand-binding and targeting properties of the receptors
DC-SIGN and DC-SIGNR Nat.Struct.Mol.Biol., 11, 2004
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6E74
| Structure of Human Transthyretin Leu55Pro Mutant in Complex with Tafamidis | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | 著者 | Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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1SL1
| Binary 5' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template | 分子名称: | 5'-D(*CP*CP*C*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*TP*(2DA))-3', DNA polymerase, ... | 著者 | Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T. | 登録日 | 2004-03-05 | 公開日 | 2004-07-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Nat.Struct.Mol.Biol., 11, 2004
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1SN2
| Crystal Structure of Sea Bream Transthyretin at 1.90A Resolution | 分子名称: | SULFATE ION, transthyretin | 著者 | Eneqvist, T, Lundberg, E, Karlsson, A, Huang, S, Cantos, C.R, Power, D.M, Sauer-Eriksson, A.E. | 登録日 | 2004-03-10 | 公開日 | 2004-08-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | High resolution crystal structures of piscine transthyretin reveal different binding modes for triiodothyronine and thyroxine. J.Biol.Chem., 279, 2004
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6O9X
| Structure of human PARG complexed with JA2-4 | 分子名称: | 1,3-dimethyl-8-{[2-(pyrrolidin-1-yl)ethyl]sulfanyl}-6-sulfanylidene-1,3,6,9-tetrahydro-2H-purin-2-one, Poly(ADP-ribose) glycohydrolase | 著者 | Stegeman, R.A, Jones, D.E, Ellenberger, T, Kim, I.K, Tainer, J.A. | 登録日 | 2019-03-15 | 公開日 | 2019-12-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death. Nat Commun, 10, 2019
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