6E74

Structure of Human Transthyretin Leu55Pro Mutant in Complex with Tafamidis

Summary for 6E74

• Entry DOI: 10.2210/pdb6e74/pdb
• Descriptor: Transthyretin, 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid (3 entities in total)
• Functional Keywords: human transthyretin, amyloid, transthyretin, tafamidis, transport protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 25796.35

Authors

Saelices, L.,Chung, K.,Sawaya, M.R.,Cascio, D.,Eisenberg, D. (deposition date: 2018-07-25, release date: 2019-07-31, Last modification date: 2024-03-13)

• Primary citation: Saelices, L.,Chung, K.,Esswein, S.,Chou, J.,Liang, W.,Li, J.H.,Sawaya, M.R.,Cascio, D.,Eisenberg, D.; Structural Variants of Transthyretin; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)