Crystal Structure of Sea Bream Transthyretin in complex with Triiodothyronine at 1.90A Resolution

Summary for 1SN5

Related1sn0 1sn2
Descriptortransthyretin, SULFATE ION, 3,5,3'TRIIODOTHYRONINE, ... (4 entities in total)
Functional Keywordstransport protein
Biological sourceSparus aurata (gilthead seabream)
Total number of polymer chains4
Total molecular weight57508.33
Eneqvist, T.,Lundberg, E.,Karlsson, A.,Huang, S.,Cantos, C.R.,Power, D.M.,Sauer-Eriksson, A.E. (deposition date: 2004-03-10, release date: 2004-08-03, Last modification date: 2014-04-30)
Primary citation
Eneqvist, T.,Lundberg, E.,Karlsson, A.,Huang, S.,Santos, C.R.,Power, D.M.,Sauer-Eriksson, A.E.
High resolution crystal structures of piscine transthyretin reveal different binding modes for triiodothyronine and thyroxine.
J.Biol.Chem., 279:26411-26416, 2004
PubMed: 15082720 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M313553200
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers120 3.7% 8.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-12-02