1SN5
Crystal Structure of Sea Bream Transthyretin in complex with Triiodothyronine at 1.90A Resolution
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005179 | molecular_function | hormone activity |
A | 0005576 | cellular_component | extracellular region |
A | 0006144 | biological_process | purine nucleobase metabolic process |
A | 0007165 | biological_process | signal transduction |
A | 0070324 | molecular_function | thyroid hormone binding |
B | 0005179 | molecular_function | hormone activity |
B | 0005576 | cellular_component | extracellular region |
B | 0006144 | biological_process | purine nucleobase metabolic process |
B | 0007165 | biological_process | signal transduction |
B | 0070324 | molecular_function | thyroid hormone binding |
C | 0005179 | molecular_function | hormone activity |
C | 0005576 | cellular_component | extracellular region |
C | 0006144 | biological_process | purine nucleobase metabolic process |
C | 0007165 | biological_process | signal transduction |
C | 0070324 | molecular_function | thyroid hormone binding |
D | 0005179 | molecular_function | hormone activity |
D | 0005576 | cellular_component | extracellular region |
D | 0006144 | biological_process | purine nucleobase metabolic process |
D | 0007165 | biological_process | signal transduction |
D | 0070324 | molecular_function | thyroid hormone binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 701 |
Chain | Residue |
A | HIS102 |
A | HIS104 |
A | SER123 |
A | SER124 |
A | HOH726 |
B | ARG103 |
site_id | AC2 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE T3 C 601 |
Chain | Residue |
A | ALA108 |
A | LEU109 |
A | LEU110 |
A | VAL121 |
A | HOH714 |
C | LYS15 |
C | LEU17 |
C | GLU54 |
C | ALA108 |
C | LEU109 |
C | LEU110 |
C | VAL121 |
C | HOH613 |
C | HOH660 |
C | HOH671 |
A | LYS15 |
A | LEU17 |
A | GLU54 |
site_id | AC3 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE T3 D 602 |
Chain | Residue |
B | LYS15 |
B | LEU17 |
B | GLU54 |
B | ALA108 |
B | LEU109 |
B | LEU110 |
B | VAL121 |
D | LYS15 |
D | LEU17 |
D | GLU54 |
D | ALA108 |
D | LEU109 |
D | LEU110 |
D | HOH615 |