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1SN5

Crystal Structure of Sea Bream Transthyretin in complex with Triiodothyronine at 1.90A Resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0005179molecular_functionhormone activity
A0005576cellular_componentextracellular region
A0006144biological_processpurine nucleobase metabolic process
A0007165biological_processsignal transduction
A0070324molecular_functionthyroid hormone binding
B0005179molecular_functionhormone activity
B0005576cellular_componentextracellular region
B0006144biological_processpurine nucleobase metabolic process
B0007165biological_processsignal transduction
B0070324molecular_functionthyroid hormone binding
C0005179molecular_functionhormone activity
C0005576cellular_componentextracellular region
C0006144biological_processpurine nucleobase metabolic process
C0007165biological_processsignal transduction
C0070324molecular_functionthyroid hormone binding
D0005179molecular_functionhormone activity
D0005576cellular_componentextracellular region
D0006144biological_processpurine nucleobase metabolic process
D0007165biological_processsignal transduction
D0070324molecular_functionthyroid hormone binding
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 701
ChainResidue
AHIS102
AHIS104
ASER123
ASER124
AHOH726
BARG103

site_idAC2
Number of Residues18
DetailsBINDING SITE FOR RESIDUE T3 C 601
ChainResidue
AALA108
ALEU109
ALEU110
AVAL121
AHOH714
CLYS15
CLEU17
CGLU54
CALA108
CLEU109
CLEU110
CVAL121
CHOH613
CHOH660
CHOH671
ALYS15
ALEU17
AGLU54

site_idAC3
Number of Residues14
DetailsBINDING SITE FOR RESIDUE T3 D 602
ChainResidue
BLYS15
BLEU17
BGLU54
BALA108
BLEU109
BLEU110
BVAL121
DLYS15
DLEU17
DGLU54
DALA108
DLEU109
DLEU110
DHOH615

222415

PDB entries from 2024-07-10

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