1SME
PLASMEPSIN II, A HEMOGLOBIN-DEGRADING ENZYME FROM PLASMODIUM FALCIPARUM, IN COMPLEX WITH PEPSTATIN A
Summary for 1SME
Entry DOI | 10.2210/pdb1sme/pdb |
Related PRD ID | PRD_000557 |
Descriptor | PLASMEPSIN II, Pepstatin (3 entities in total) |
Functional Keywords | aspartyl proteinase, aspartic proteinase, aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Plasmodium falciparum (malaria parasite P. falciparum) More |
Cellular location | Vacuole: P46925 |
Total number of polymer chains | 4 |
Total formula weight | 75279.25 |
Authors | Silva, A.M.,Lee, A.Y.,Gulnik, S.V.,Goldberg, D.E.,Erickson, J.W. (deposition date: 1996-06-11, release date: 1997-01-11, Last modification date: 2023-11-15) |
Primary citation | Silva, A.M.,Lee, A.Y.,Gulnik, S.V.,Maier, P.,Collins, J.,Bhat, T.N.,Collins, P.J.,Cachau, R.E.,Luker, K.E.,Gluzman, I.Y.,Francis, S.E.,Oksman, A.,Goldberg, D.E.,Erickson, J.W. Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum. Proc.Natl.Acad.Sci.USA, 93:10034-10039, 1996 Cited by PubMed: 8816746DOI: 10.1073/pnas.93.19.10034 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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