Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR CHAIN C OF PEPSTATIN |
| Chain | Residue |
| A | ASP34 |
| A | GLY216 |
| A | THR217 |
| A | SER218 |
| A | ILE290 |
| B | LEU242 |
| A | GLY36 |
| A | ASN76 |
| A | TYR77 |
| A | VAL78 |
| A | SER79 |
| A | ILE123 |
| A | TYR192 |
| A | ASP214 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR CHAIN D OF PEPSTATIN |
| Chain | Residue |
| A | PHE241 |
| A | LEU242 |
| B | ASP34 |
| B | GLY36 |
| B | SER37 |
| B | ASN76 |
| B | TYR77 |
| B | VAL78 |
| B | SER79 |
| B | ILE123 |
| B | TYR192 |
| B | ASP214 |
| B | GLY216 |
| B | THR217 |
| B | SER218 |
| B | ILE290 |
| B | LEU292 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. FILDTGSANLWV |
| Chain | Residue | Details |
| A | PHE31-VAL42 | |
| A | CYS211-VAL222 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 614 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | a catalytic site defined by CSA, PubMed 8816746, 9561243, 11714911 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | ASP214 | |
| A | SER37 | |
| A | THR217 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | a catalytic site defined by CSA, PubMed 8816746, 9561243, 11714911 |
| Chain | Residue | Details |
| B | ASP34 | |
| B | ASP214 | |
| B | SER37 | |
| B | THR217 | |
