2X70
| Crystal structure of MHC CLass I HLA-A2.1 bound to a photocleavable peptide | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ... | 著者 | Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M. | 登録日 | 2010-02-22 | 公開日 | 2010-12-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Uv-Induced Ligand Exchange in Mhc Class I Protein Crystals. J.Am.Chem.Soc., 131, 2009
|
|
3KPN
| Crystal Structure of HLA B*4403 in complex with EEYLQAFTY a self peptide from the ABCD3 protein | 分子名称: | Beta-2-microglobulin, EEYLQAFTY, self peptide from the ATP binding cassette protein ABCD3, ... | 著者 | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | 登録日 | 2009-11-16 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | T cell allorecognition via molecular mimicry. Immunity, 31, 2009
|
|
6C6H
| Structure of glycolipid aGSA[8,P5m] in complex with mouse CD1d | 分子名称: | (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(3-pentylphenyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)te trahydro-2H-pyran-2-yl]oxy}octanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | 著者 | Zajonc, D.M, Wang, J. | 登録日 | 2018-01-18 | 公開日 | 2019-01-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides. J.Biol.Chem., 294, 2019
|
|
3AVE
| Crystal Structure of the Fucosylated Fc Fragment from Human Immunoglobulin G1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, ZINC ION | 著者 | Matsumiya, S, Yamaguchi, Y, Saito, J, Nagano, M, Sasakawa, H, Otaki, S, Satoh, M, Shitara, K, Kato, K. | 登録日 | 2011-03-04 | 公開日 | 2011-04-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Corrigendum to "Structural Comparison of Fucosylated and Nonfucosylated Fc Fragments of Human Immunoglobulin G1" [J. Mol. Biol. 386/3 (2007) 767-779] J.Mol.Biol., 408, 2011
|
|
3HPJ
| |
8GLF
| |
1YEG
| STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH REACTION PRODUCT | 分子名称: | ACETATE ION, IGG2A FAB FRAGMENT, PARANITROBENZYL ALCOHOL, ... | 著者 | Gigant, B, Knossow, M. | 登録日 | 1997-05-29 | 公開日 | 1997-12-03 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release. Proc.Natl.Acad.Sci.USA, 94, 1997
|
|
4PJ9
| Structure of human MR1-5-OP-RU in complex with human MAIT TRAJ20 TCR | 分子名称: | 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Birkinshaw, R.W, Rossjohn, J. | 登録日 | 2014-05-12 | 公開日 | 2014-07-02 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells. J.Exp.Med., 211, 2014
|
|
3P9M
| Crystal Structure of H2-Kb in complex with a mutant of the chicken ovalbumin epitope OVA-G4 | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... | 著者 | Wesselingh, R, Gras, S, Guillonneau, C, Turner, S.J, Rossjohn, J. | 登録日 | 2010-10-18 | 公開日 | 2011-10-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses J.Immunol., 187, 2011
|
|
6CPN
| Crystal structure of DR11 presenting the RQ13 peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gag polyprotein, ... | 著者 | Farenc, C, Gras, S, Rossjohn, J. | 登録日 | 2018-03-13 | 公開日 | 2018-06-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | CD4+T cell-mediated HLA class II cross-restriction in HIV controllers. Sci Immunol, 3, 2018
|
|
4L4T
| Structure of human MAIT TCR in complex with human MR1-6-FP | 分子名称: | 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde, Beta-2-microglobulin, MAIT T-cell receptor alpha chain, ... | 著者 | Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J. | 登録日 | 2013-06-09 | 公開日 | 2013-07-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nat Commun, 4, 2013
|
|
6UGW
| Crystal structure of the Fc fragment of PF06438179/GP1111 an infliximab biosimilar in a C-centered orthorhombic crystal form, Lot A | 分子名称: | ACETATE ION, PF-06438179/GP1111 Fc, ZINC ION, ... | 著者 | Mayclin, S.J, Edwards, T.E. | 登録日 | 2019-09-26 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. BioDrugs, 34, 2020
|
|
5MOK
| Crystal structure of human IgE-Fc epsilon 3-4 | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ig epsilon chain C region, ... | 著者 | Dore, K.A, Davies, A.M, Drinkwater, N, Beavil, A.J, McDonnell, J.M, Sutton, B.J. | 登録日 | 2016-12-14 | 公開日 | 2018-01-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Thermal sensitivity and flexibility of the C epsilon 3 domains in immunoglobulin E. Biochim. Biophys. Acta, 1865, 2017
|
|
1D5I
| UNLIGANDED GERMLINE PRECURSOR OF AN OXY-COPE CATALYTIC ANTIBODY | 分子名称: | CADMIUM ION, CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (HEAVY CHAIN), CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (LIGHT CHAIN) | 著者 | Mundorff, E.C, Hanson, M.A, Schultz, P.G, Stevens, R.C. | 登録日 | 1999-10-07 | 公開日 | 2000-02-09 | 最終更新日 | 2017-06-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement. Biochemistry, 39, 2000
|
|
5DJ6
| Fc Heterodimer Design 6.1 F405W/Y407A + T366M | 分子名称: | Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B. | 登録日 | 2015-09-01 | 公開日 | 2016-03-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
|
|
3X14
| Crystal structure of HLA-B*0801.N80I.R82L.G83R | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ... | 著者 | Vivian, J.P, Rossjohn, J. | 登録日 | 2014-10-25 | 公開日 | 2014-12-24 | 最終更新日 | 2015-04-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope J.Immunol., 194, 2015
|
|
3GIV
| Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance | 分子名称: | Beta-2-microglobulin, HIV-1 peptide, HLA class I histocompatibility antigen, ... | 著者 | Stewart-Jones, G, Iversen, A.K.N, Jones, E.Y. | 登録日 | 2009-03-06 | 公開日 | 2009-06-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance Nat.Immunol., 10, 2009
|
|
3RL1
| HIV RT derived peptide complexed to HLA-A*0301 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-3 alpha chain, ... | 著者 | Zhang, S, Liu, J, Cheng, H, Tan, S, Qi, J, Yan, J, Gao, G.F. | 登録日 | 2011-04-19 | 公開日 | 2012-02-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes Mol.Immunol., 49, 2011
|
|
7RHO
| |
3DHJ
| Beta 2 microglobulin mutant W60C | 分子名称: | Beta-2-microglobulin | 著者 | Ricagno, S, Colombo, M, de Rosa, M, Bolognesi, M, Giorgetti, S, Bellotti, V. | 登録日 | 2008-06-18 | 公開日 | 2008-11-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | DE loop mutations affect beta2-microglobulin stability and amyloid aggregation Biochem.Biophys.Res.Commun., 377, 2008
|
|
3DRQ
| Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 FP-MPER Hyb3K construct 514GIGALFLGFLGAAGS528KK-Ahx-655KNEQELLELDKWASLWN671 soaked in PEG/2-propanol solution | 分子名称: | 2F5 Fab' heavy chain, 2F5 Fab' light chain, GLYCEROL, ... | 著者 | Bryson, S, Julien, J.P, Pai, E.F. | 登録日 | 2008-07-11 | 公開日 | 2008-10-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. J.Mol.Biol., 384, 2008
|
|
3LKR
| Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 2009 H1N1 swine origin strain | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | 著者 | Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K. | 登録日 | 2010-01-27 | 公開日 | 2010-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
1YEF
| STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH SUBSTRATE ANALOGUE | 分子名称: | IGG2A FAB FRAGMENT, PARA-NITROBENZYL GLUTARYL GLYCINIC ACID, ZINC ION | 著者 | Gigant, B, Knossow, M. | 登録日 | 1997-05-29 | 公開日 | 1997-12-03 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release. Proc.Natl.Acad.Sci.USA, 94, 1997
|
|
1A1N
| MHC CLASS I MOLECULE B*3501 COMPLEXED WITH PEPTIDE VPLRPMTY FROM THE NEF PROTEIN (75-82) OF HIV1 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, BW-53 B*5301 alpha chain, ... | 著者 | Smith, K.J, Reid, S.W, Stuart, D.I, Mcmichael, A.J, Jones, E.Y, Bell, J.I. | 登録日 | 1997-12-11 | 公開日 | 1998-04-08 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501. Immunity, 4, 1996
|
|
1JUF
| Structure of Minor Histocompatibility Antigen peptide, H13b, complexed to H2-Db | 分子名称: | Beta-2-microglobulin, H13b peptide, H2-Db major histocompatibility antigen | 著者 | Ostrov, D.A, Roden, M.M, Shi, W, Palmieri, E, Christianson, G.J, Mendoza, L, Villaflor, G, Tilley, D, Shastri, N, Grey, H, Almo, S.C, Roopenian, D.C, Nathenson, S.G. | 登録日 | 2001-08-24 | 公開日 | 2002-03-20 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination. J.Immunol., 168, 2002
|
|