7RHO

Human IgG1 Fc fragment, hinge-free, expressed in E. coli

Summary for 7RHO

Entry DOI	10.2210/pdb7rho/pdb
Descriptor	Fc fragment of human IgG1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (3 entities in total)
Functional Keywords	immunoglobulin fc fragment, e. coli, bacterial expression, aglycosylated, immune system
Biological source	Homo sapiens (Human)
Total number of polymer chains	8
Total formula weight	193695.48
Authors	Gallagher, D.T. (deposition date: 2021-07-18, release date: 2022-11-09, Last modification date: 2023-11-22)
Primary citation	Bergonzo, C.,Hoopes, J.T.,Kelman, Z.,Gallagher, D.T. Effects of glycans and hinge on dynamics in the IgG1 Fc. J.Biomol.Struct.Dyn., :1-9, 2023 Cited by PubMed: 37897185 DOI: 10.1080/07391102.2023.2270749 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation