8GLF

Crystal Structure of Human CD1b in Complex with Sphingomyelin C34:2

Summary for 8GLF

• Entry DOI: 10.2210/pdb8glf/pdb
• Descriptor: T-cell surface glycoprotein CD1b, NICKEL (II) ION, Beta-2-microglobulin, ... (11 entities in total)
• Functional Keywords: immune system, lipid, cd1b, sphingomyelin
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 49008.20

Authors

Shahine, A. (deposition date: 2023-03-22, release date: 2023-09-20, Last modification date: 2024-05-01)

• Primary citation: Huang, S.,Shahine, A.,Cheng, T.Y.,Chen, Y.L.,Ng, S.W.,Balaji, G.R.,Farquhar, R.,Gras, S.,Hardman, C.S.,Altman, J.D.,Tahiri, N.,Minnaard, A.J.,Ogg, G.S.,Mayfield, J.A.,Rossjohn, J.,Moody, D.B.; CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.; Cell, 186:4583-4596.e13, 2023; PubMed: 37725977; DOI: 10.1016/j.cell.2023.08.022

Experimental method

X-RAY DIFFRACTION (2 Å)