3DHJ

Beta 2 microglobulin mutant W60C

Summary for 3DHJ

Entry DOI	10.2210/pdb3dhj/pdb
Related	2z9t 3DHM
Descriptor	Beta-2-microglobulin (2 entities in total)
Functional Keywords	beta-2-microglobulin, tryptophan, glycine, amyloidosis, dra, beta fibrils, disease mutation, glycation, glycoprotein, immune response, immunoglobulin domain, mhc i, pyrrolidone carboxylic acid, secreted, immune system
Biological source	Homo sapiens (Human)
Cellular location	Secreted: P61769
Total number of polymer chains	1
Total formula weight	11796.29
Authors	Ricagno, S.,Colombo, M.,de Rosa, M.,Bolognesi, M.,Giorgetti, S.,Bellotti, V. (deposition date: 2008-06-18, release date: 2008-11-18, Last modification date: 2023-11-01)
Primary citation	Ricagno, S.,Colombo, M.,de Rosa, M.,Sangiovanni, E.,Giorgetti, S.,Raimondi, S.,Bellotti, V.,Bolognesi, M. DE loop mutations affect beta2-microglobulin stability and amyloid aggregation Biochem.Biophys.Res.Commun., 377:146-150, 2008 Cited by PubMed: 18835253 DOI: 10.1016/j.bbrc.2008.09.108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation