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1EJO
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FAB FRAGMENT OF NEUTRALISING MONOCLONAL ANTIBODY 4C4 COMPLEXED WITH G-H LOOP FROM FMDV.
分子名称: FMDV PEPTIDE, IGG2A MONOCLONAL ANTIBODY (HEAVY CHAIN), IGG2A MONOCLONAL ANTIBODY (LIGHT CHAIN)
著者Ochoa, W.F, Kalko, S.G, Gomes, P, Fita, I, Verdaguer, N.
登録日2000-03-03
公開日2000-03-22
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A multiply substituted G-H loop from foot-and-mouth disease virus in complex with a neutralizing antibody: a role for water molecules.
J.Gen.Virol., 81, 2000
1GIG
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REFINED THREE-DIMENSIONAL STRUCTURE OF THE FAB FRAGMENT OF A MURINE IGG1, LAMBDA ANTIBODY
分子名称: IGG1-KAPPA HC19 FAB (HEAVY CHAIN), IGG1-KAPPA HC19 FAB (LIGHT CHAIN)
著者Bizebard, T, Knossow, M.
登録日1993-01-20
公開日1994-04-30
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Refined three-dimensional structure of the Fab fragment of a murine IgGl,lambda antibody.
Acta Crystallogr.,Sect.D, 50, 1994
6V7Y
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Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ...
著者Shahine, A, Rossjohn, J.
登録日2019-12-10
公開日2020-09-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response.
Nat Cancer, 2020
1H3P
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STRUCTURAL CHARACTERISATION OF A MONOCLONAL ANTIBODY SPECIFIC FOR THE PRES1 REGION OF THE HEPATITIS B VIRUS
分子名称: ANTIBODY FAB FRAGMENT
著者Pizarro, J.C, Vulliez-Le-normand, B, Riottot, M.M, Budkowska, A, Bentley, G.A.
登録日2002-09-12
公開日2002-09-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Functional Characterisation of a Monoclonal Antibody Specific for the Pres1 Region of Hepatitis B Virus
FEBS Lett., 509, 2001
1GZP
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CD1b in complex with GM2 ganglioside
分子名称: B2-MICROGLOBULIN, DOCOSANE, DODECANE, ...
著者Gadola, S.D, Zaccai, N.R, Harlos, K, Shepherd, D, Ritter, G, Schmidt, R.R, Jones, E.Y, Cerundolo, V.
登録日2002-05-24
公開日2002-07-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains.
Nat. Immunol., 3, 2002
1F6A
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Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)ri(alpha)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
著者Garman, S.C, Wurzburg, B.A, Tarchevskaya, S.S, Kinet, J.P, Jardetzky, T.S.
登録日2000-06-20
公開日2000-07-20
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc (epsilon) RI (alpha).
Nature, 406, 2000
1GZQ
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CD1b in complex with Phophatidylinositol
分子名称: 2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE, B2-MICROGLOBULIN, DOCOSANE, ...
著者Gadola, S.D, Zaccai, N.R, Harlos, K, Shepherd, D, Ritter, G, Schmidt, R.R, Jones, E.Y, Cerundolo, V.
登録日2002-05-24
公開日2002-07-31
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structure of Human Cd1B with Bound Ligands at 2.3 A, a Maze for Alkyl Chains
Nat.Immunol., 3, 2002
6AL5
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COMPLEX BETWEEN CD19 (N138Q MUTANT) AND B43 FAB
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, B-lymphocyte antigen CD19, B43 HEAVY CHAIN, ...
著者Teplyakov, A, Obmolova, G, Gilliland, G.L.
登録日2017-08-07
公開日2018-03-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of B-cell co-receptor CD19 in complex with antibody B43 reveals an unexpected fold.
Proteins, 86, 2018
6AL4
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CRYSTAL STRUCTURE OF ANTI-CD19 ANTIBODY B43 FAB
分子名称: B43 HEAVY CHAIN, B43 LIGHT CHAIN
著者Teplyakov, A, Obmolova, G, Gilliland, G.L.
登録日2017-08-07
公開日2018-03-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of B-cell co-receptor CD19 in complex with antibody B43 reveals an unexpected fold.
Proteins, 86, 2018
6AU5
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Structure of cetuximab with aminoheptanoic acid-linked n-butylarginine meditope variant
分子名称: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ...
著者Bzymek, K.P, Williams, J.C.
登録日2017-08-30
公開日2017-12-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.484 Å)
主引用文献Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6APC
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BU of 6apc by Molmil
Crystal Structure of Infant Antibody ADI-19425
分子名称: Epididymis luminal protein 214, IGL@ protein, SULFATE ION
著者Gilman, M.S.A, McLellan, J.S.
登録日2017-08-17
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation.
Immunity, 48, 2018
6ARP
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BU of 6arp by Molmil
Structure of a mutant Cetuximab Fab fragment
分子名称: Cetuximab mutant Fab heavy chain,Immunoglobulin gamma-1 heavy chain, Cetuximab mutant light chain,Uncharacterized protein, GLYCEROL, ...
著者Christie, M, Christ, D.
登録日2017-08-23
公開日2018-08-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of a mutant Cetuximab Fab fragment
To Be Published
6AT6
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BU of 6at6 by Molmil
Crystal structure of the KFJ5 TCR
分子名称: T-cell receptor alpha variable 4, T-cell receptor, sp3.4 alpha chain chimera, ...
著者Gully, B.S, Rossjohn, J.
登録日2017-08-28
公開日2018-02-28
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.417 Å)
主引用文献Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.
Nat Commun, 9, 2018
6AXP
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BU of 6axp by Molmil
Structure of cetuximab with aminoheptanoic acid-linked n-octylarginine meditope variant
分子名称: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ...
著者Bzymek, K.P, Williams, J.C.
登録日2017-09-07
公開日2017-12-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.484 Å)
主引用文献Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6AZL
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BU of 6azl by Molmil
Structure of cetuximab with aminoheptanoic acid-linked N-carboxyethylarginine meditope variant
分子名称: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ...
著者Bzymek, K.P, Williams, J.C.
登録日2017-09-11
公開日2017-12-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.482 Å)
主引用文献Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6C6A
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BU of 6c6a by Molmil
Structure of glycolipid aGSA[16,6P] in complex with mouse CD1d
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Zajonc, D.M, Wang, J.
登録日2018-01-18
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
6C6F
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Structure of glycolipid aGSA[26,P5p] in complex with mouse CD1d
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, ...
著者Zajonc, D.M, Wang, J.
登録日2018-01-18
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structure-function analysis of sphingamides
To Be Published
6C5H
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S25-5 Fab in complex with Chlamydiaceae-specific LPS antigen
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Evans, S.V, Haji-Ghassemi, O.
登録日2018-01-16
公開日2019-01-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Biochemistry, 58, 2019
6C5M
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Structure of glycolipid aGSA[8,9] in complex with mouse CD1d
分子名称: (5R,6S,7S)-5,6-dihydroxy-N-nonyl-7-(octanoylamino)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octanamide (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zajonc, D.M, Wang, J.
登録日2018-01-16
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
6C5K
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S25-23 Fab in complex with Chlamydiaceae LPS (Crystal form 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, IgG1 Fab Heavy Chain, ...
著者Haji-Ghassemi, O, Evans, S.V.
登録日2018-01-16
公開日2019-01-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Biochemistry, 58, 2019
6C6J
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Structure of glycolipid aGSA[8,P5p] in complex with mouse CD1d
分子名称: (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(4-pentylphenyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)te trahydro-2H-pyran-2-yl]oxy}octanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Zajonc, D.M, Wang, J.
登録日2018-01-18
公開日2019-01-30
最終更新日2020-08-19
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
6C09
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Ternary crystal structure of the 3C8 TCR-CD1c-monoacylglycerol complex
分子名称: (2R)-2,3-dihydroxypropyl hexadecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wun, K.S, Rossjohn, J.
登録日2017-12-28
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.
Nat. Immunol., 19, 2018
6C6C
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Structure of glycolipid aGSA[20,6P] in complex with mouse CD1d
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, ...
著者Zajonc, D.M, Wang, J.
登録日2018-01-18
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
6C6H
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BU of 6c6h by Molmil
Structure of glycolipid aGSA[8,P5m] in complex with mouse CD1d
分子名称: (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(3-pentylphenyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)te trahydro-2H-pyran-2-yl]oxy}octanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Zajonc, D.M, Wang, J.
登録日2018-01-18
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
6C5I
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Unliganded S25-5 Fab
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Evans, S.V, Haji-Ghassemi, O.
登録日2018-01-16
公開日2019-01-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Biochemistry, 58, 2019

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