6C5H

S25-5 Fab in complex with Chlamydiaceae-specific LPS antigen

Summary for 6C5H

Entry DOI	10.2210/pdb6c5h/pdb
Descriptor	Fab Heavy Chain (IgG1), Fab Light Chain (IgG1 Kappa), alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywords	complex, lipopolysaccharide, antibody, antigen, chlamydia, sugar binding protein, immune system
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	2
Total formula weight	49806.53
Authors	Evans, S.V.,Haji-Ghassemi, O. (deposition date: 2018-01-16, release date: 2019-01-09, Last modification date: 2023-10-04)
Primary citation	Haji-Ghassemi, O.,Muller-Loennies, S.,Brooks, C.L.,MacKenzie, C.R.,Caveney, N.,Van Petegem, F.,Brade, L.,Kosma, P.,Brade, H.,Evans, S.V. Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude. Biochemistry, 58:714-726, 2019 Cited by PubMed: 30571096 DOI: 10.1021/acs.biochem.8b00318 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation