PDB: 66478 件ウェブページステータス検索Chemie searchBIRD

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3SHU	Crystal structure of ZO-1 PDZ3 分子名称: Tight junction protein ZO-1 著者 Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M. 登録日 2011-06-17 公開日 2011-09-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core To be Published
3SJ7	Structure of beta-ketoacetyl-CoA reductase (FabG) from Staphylococcus aureus complex with NADPH 分子名称: 3-oxoacyl-(Acyl-carrier-protein) reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TETRAETHYLENE GLYCOL 著者 Dutta, D, Bhattacharyya, S, Das, A.K. 登録日 2011-06-21 公開日 2012-01-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure and fluorescence studies reveal the role of helical dimeric interface of staphylococcal fabg1 in positive cooperativity for NADPH. Proteins, 80, 2012
3U6W	Truncated M. tuberculosis LeuA (1-425) complexed with KIV 分子名称: 2-isopropylmalate synthase, 3-METHYL-2-OXOBUTANOIC ACID, GLYCEROL, ... 著者 Koon, N, Baker, E.N, Squire, C.J. 登録日 2011-10-13 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Removal of the C-terminal regulatory domain of alpha-isopropylmalate synthase disrupts functional substrate binding. Biochemistry, 51, 2012
2HL8	SUMO protease Ulp1 with the catalytic cysteine oxidized to a sulfinic acid 分子名称: Ubiquitin-like-specific protease 1 著者 Xu, Z, Ng, T.B, Au, S.W.N. 登録日 2006-07-06 公開日 2007-07-31 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis of the redox regulation of SUMO proteases: a protective mechanism of intermolecular disulfide linkage against irreversible sulfhydryl oxidation Faseb J., 22, 2008
2HKP	SUMO protease Ulp1 with the catalytic cysteine oxidized to a sulfenic acid 分子名称: Ubiquitin-like-specific protease 1 著者 Xu, Z, Ng, T.B, Au, S.W.N. 登録日 2006-07-05 公開日 2007-07-31 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular basis of the redox regulation of SUMO proteases: a protective mechanism of intermolecular disulfide linkage against irreversible sulfhydryl oxidation Faseb J., 22, 2008
3RB9	Crystal structure of the M. tuberculosis beta clamp 分子名称: DNA polymerase III subunit beta 著者 Kukshal, V, Ramachandran, R. 登録日 2011-03-29 公開日 2012-04-04 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 M. tuberculosis Sliding beta-Clamp Does Not Interact Directly with the NAD(+)-Dependent DNA Ligase Plos One, 7, 2012
3TD6	Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis from trigonal partially dehydrated crystal 分子名称: Peptidyl-tRNA hydrolase 著者 Selvaraj, M, Ahmad, R, Varshney, U, Vijayan, M. 登録日 2011-08-10 公開日 2012-02-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structures of new crystal forms of Mycobacterium tuberculosis peptidyl-tRNA hydrolase and functionally important plasticity of the molecule Acta Crystallogr.,Sect.F, 68, 2012
3TFM	Myosin X PH1N-PH2-PH1C tandem 分子名称: Myosin X, PHOSPHATE ION 著者 Yu, J, Lu, Q, Yan, J, Wei, Z, Zhang, M. 登録日 2011-08-16 公開日 2011-12-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensor MOLECULAR BIOLOGY OF THE CELL, 22, 2011
3UAM	Crystal structure of a chitin binding domain from Burkholderia pseudomallei 分子名称: Chitin binding domain, GLYCEROL, NITRATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-10-21 公開日 2011-11-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a chitin binding domain from Burkholderia pseudomallei to be published
3TK5	Factor Xa in complex with D102-4380 分子名称: 4-{3-[(4-chlorophenyl)amino]-3-oxopropyl}-3-({[5-(propan-2-yl)-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl]carbonyl}amino)benzoic acid, CALCIUM ION, Factor X heavy chain, ... 著者 Suzuki, M, Mochizuki, A, Nagata, T, Takano, H, Kanno, H, Kishida, M, Ohta, T. 登録日 2011-08-25 公開日 2012-08-29 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Zwitter ionic potent durable orally active Factor Xa inhibitor. To be Published
3TZ6	Crystal structure of Aspartate semialdehyde dehydrogenase Complexed With inhibitor SMCS (CYS) And Phosphate From Mycobacterium tuberculosis H37Rv 分子名称: Aspartate-semialdehyde dehydrogenase, CYSTEINE, GLYCEROL, ... 著者 Vyas, R, Tewari, R, Weiss, M.S, Karthikeyan, S. 登録日 2011-09-27 公開日 2012-05-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structures of ternary complexes of aspartate-semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis H37Rv Acta Crystallogr.,Sect.D, 68, 2012
2GHI	Crystal Structure of Plasmodium yoelii Multidrug Resistance Protein 2 分子名称: SULFATE ION, transport protein 著者 Dong, A, Gao, M, Choe, J, Zhao, Y, Lew, J, Wasney, G, Alam, Z, Melone, M, Kozieradzki, I, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC) 登録日 2006-03-27 公開日 2006-04-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
3QI1	Design and synthesis of hydroxyethylamine (hea) BACE-1 inhibitors: prime side chromane-containing inhibitors 分子名称: Beta-secretase 1, N-[(2S,3R)-4-{[(2R,4S)-2-cyclopropyl-6-(2,2-dimethylpropyl)-3,4-dihydro-2H-chromen-4-yl]amino}-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]acetamide 著者 Yao, N. 登録日 2011-01-26 公開日 2012-03-28 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
3QKD	Crystal structure of Bcl-xL in complex with a Quinazoline sulfonamide inhibitor 分子名称: (R)-N-(7-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)quinazolin-4-yl)-4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrobenzenesulfonamide, Bcl-2-like protein 1, CHLORIDE ION, ... 著者 Czabotar, P.E, Smith, B.J. 登録日 2011-01-31 公開日 2011-04-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activity. J.Med.Chem., 54, 2011
3QVT	L-myo-inositol 1-phosphate synthase from Archaeoglobus fulgidus wild-type with the intermediate 5-keto 1-phospho glucose 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, Myo-inositol-1-phosphate synthase (Ino1), ... 著者 Neelon, K, Roberts, M.F, Stec, B. 登録日 2011-02-25 公開日 2012-01-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a trapped catalytic intermediate suggests that forced atomic proximity drives the catalysis of mIPS. Biophys.J., 101, 2011
3Q6I	Crystal structure of FabG4 and coenzyme binary complex 分子名称: (2S,5R,8R,11S,14S,17S,21R)-5,8,11,14,17-PENTAMETHYL-4,7,10,13,16,19-HEXAOXADOCOSANE-2,21-DIOL, 3-oxoacyl-(Acyl-carrier-protein) reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Dutta, D, Bhattacharyya, S, Das, A.K. 登録日 2011-01-01 公開日 2012-01-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Crystal structure of holoFabG4 To be Published
3QPY	Crystal structure of a mutant (K57A) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, GLYCEROL, ... 著者 Allison, T.M, Jameson, G.B, Parker, E.J. 登録日 2011-02-14 公開日 2011-04-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase Biochemistry, 50, 2011
3TKT	Crystal structure of CYP108D1 from Novosphingobium aromaticivorans DSM12444 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Yang, W, Bell, S.G, Wang, H, Zhou, W, Bartlam, M, Wong, L.-L, Rao, Z. 登録日 2011-08-29 公開日 2012-02-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and function of CYP108D1 from Novosphingobium aromaticivorans DSM12444: an aromatic hydrocarbon-binding P450 enzyme Acta Crystallogr.,Sect.D, 68, 2012
3TOI	Tailoring Enzyme Stability and Exploiting Stability-Trait Linkage by Iterative Truncation and Optimization 分子名称: Ampicillin resistance protein 著者 Tam, H.K, Einsle, O. 登録日 2011-09-05 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Exploring the Molecular Linkage of Protein Stability Traits for Enzyme Optimization by Iterative Truncation and Evolution. Biochemistry, 51, 2012
3TTU	Structure of F413Y/H128N double variant of E. coli KatE 分子名称: Catalase HPII, PROTOPORPHYRIN IX CONTAINING FE 著者 Loewen, P.C, Jha, V. 登録日 2011-09-15 公開日 2011-10-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Mutation of Phe413 to Tyr in catalase KatE from Escherichia coli leads to side chain damage and main chain cleavage. Arch.Biochem.Biophys., 525, 2012
3U4N	A novel covalently linked insulin dimer 分子名称: Insulin A chain, Insulin B chain 著者 Norrman, M, Vinther, T.N. 登録日 2011-10-10 公開日 2012-04-11 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization. Plos One, 7, 2012
3UG8	AKR1C3 complex with indomethacin at pH 7.5 分子名称: 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member C3, INDOMETHACIN, ... 著者 Flanagan, J.U, Yosaatmadja, Y, Teague, R.M, Chai, M, Squire, C.J. 登録日 2011-11-02 公開日 2012-08-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. Plos One, 7, 2012
4U6E	HsMetAP in complex with (amino(phenyl)methyl)phosphonic acid 分子名称: COBALT (II) ION, Methionine aminopeptidase 1, [(R)-amino(phenyl)methyl]phosphonic acid 著者 Arya, T, Addlagatta, A. 登録日 2014-07-28 公開日 2015-03-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases J.Med.Chem., 58, 2015
3LJF	The X-ray structure of iron superoxide dismutase from Pseudoalteromonas haloplanktis (crystal form II) 分子名称: FE (III) ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, iron superoxide dismutase 著者 Merlino, A, Russo Krauss, I, Rossi, B, Conte, M, Vergara, A, Sica, F. 登録日 2010-01-26 公開日 2010-09-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and flexibility in cold-adapted iron superoxide dismutases: the case of the enzyme isolated from Pseudoalteromonas haloplanktis. J.Struct.Biol., 172, 2010
5WMF	Crystal structure of the Hexameric Ring of Epstein-Barr Virus Nuclear Antigen-1, EBNA1 分子名称: Epstein-Barr nuclear antigen 1 著者 Messick, T.E. 登録日 2017-07-28 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance. J. Virol., 91, 2017

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