3TOI

Tailoring Enzyme Stability and Exploiting Stability-Trait Linkage by Iterative Truncation and Optimization

Summary for 3TOI

• Entry DOI: 10.2210/pdb3toi/pdb
• Descriptor: Ampicillin resistance protein (2 entities in total)
• Functional Keywords: hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 55398.91

Authors

Tam, H.K.,Einsle, O. (deposition date: 2011-09-05, release date: 2012-05-16, Last modification date: 2023-09-13)

• Primary citation: Speck, J.,Hecky, J.,Tam, H.K.,Arndt, K.M.,Einsle, O.,Muller, K.M.; Exploring the Molecular Linkage of Protein Stability Traits for Enzyme Optimization by Iterative Truncation and Evolution.; Biochemistry, 51:4850-4867, 2012; PubMed: 22545913; DOI: 10.1021/bi2018738

Experimental method

X-RAY DIFFRACTION (1.9 Å)