3SJ7

Structure of beta-ketoacetyl-CoA reductase (FabG) from Staphylococcus aureus complex with NADPH

Summary for 3SJ7

Entry DOI	10.2210/pdb3sj7/pdb
Descriptor	3-oxoacyl-(Acyl-carrier-protein) reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TETRAETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	ketoreductase, rossmann fold, oxidoreductase
Biological source	Staphylococcus aureus subsp. aureus
Total number of polymer chains	2
Total formula weight	55842.59
Authors	Dutta, D.,Bhattacharyya, S.,Das, A.K. (deposition date: 2011-06-21, release date: 2012-01-25, Last modification date: 2024-02-28)
Primary citation	Dutta, D.,Bhattacharyya, S.,Das, A.K. Crystal structure and fluorescence studies reveal the role of helical dimeric interface of staphylococcal fabg1 in positive cooperativity for NADPH. Proteins, 80:1250-1257, 2012 Cited by PubMed: 22275129 DOI: 10.1002/prot.24024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation