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5Y28
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Crystal structure of H. pylori HtrA with PDZ2 deletion
分子名称: 1,2-ETHANEDIOL, Periplasmic serine endoprotease DegP-like, UNK-UNK-UNK-UNK
著者Zhang, Z, Huang, Q, Tao, X.
登録日2017-07-24
公開日2018-08-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.08606815 Å)
主引用文献The unique trimeric assembly of the virulence factor HtrA fromHelicobacter pylorioccurs via N-terminal domain swapping.
J.Biol.Chem., 294, 2019
1Y6X
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BU of 1y6x by Molmil
The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis
分子名称: Phosphoribosyl-ATP pyrophosphatase
著者Javid-Majd, F, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2004-12-07
公開日2005-03-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 64, 2008
5N10
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Cucurbit[8]uril and 14-3-3 based binary bivalent supramolecular-protein assembly platform
分子名称: 14-3-3 protein beta/alpha, Cucurbit[8]uril, Estrogen receptor, ...
著者de Vink, P.J, Ottmann, C.
登録日2017-02-04
公開日2017-05-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3.
Angew. Chem. Int. Ed. Engl., 56, 2017
5XZK
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Pholiota squarrosa lectin trimer
分子名称: lectin (PhoSL)
著者Yamasaki, K.
登録日2017-07-12
公開日2018-06-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The trimeric solution structure and fucose-binding mechanism of the core fucosylation-specific lectin PhoSL.
Sci Rep, 8, 2018
2B1O
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BU of 2b1o by Molmil
Solution Structure of Ca2+-bound DdCAD-1
分子名称: CALCIUM ION, Calcium-dependent cell adhesion molecule-1
著者Lin, Z, Sriskanthadevan, S, Huang, H.B, Siu, C.H, Yang, D.W.
登録日2005-09-16
公開日2006-09-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structures of the adhesion molecule DdCAD-1 reveal new insights into Ca(2+)-dependent cell-cell adhesion
Nat.Struct.Mol.Biol., 13, 2006
1Z2C
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BU of 1z2c by Molmil
Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP
分子名称: Diaphanous protein homolog 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Rose, R, Weyand, M, Lammers, M, Ishizaki, T, Ahmadian, M.R, Wittinghofer, A.
登録日2005-03-08
公開日2005-05-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and mechanistic insights into the interaction between Rho and mammalian Dia.
Nature, 435, 2005
6H1K
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BU of 6h1k by Molmil
The major G-quadruplex form of HIV-1 LTR
分子名称: DNA (28-MER)
著者Phan, A.T, Heddi, B, Butovskaya, E, Bakalar, B, Richter, S.N.
登録日2018-07-11
公開日2018-10-17
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop.
J. Am. Chem. Soc., 140, 2018
5Y1I
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The crystal structure of GfsF
分子名称: Cytochrome P450, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Miyanaga, A, Kudo, F, Eguchi, T.
登録日2017-07-20
公開日2017-09-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Substrate Recognition by a Dual-Function P450 Monooxygenase GfsF Involved in FD-891 Biosynthesis
Chembiochem, 18, 2017
5Y2D
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Crystal structure of H. pylori HtrA
分子名称: Periplasmic serine endoprotease DegP-like, UNK-UNK-K-UNK-UNK-UNK-UNK-UNK-UNK-UNK, UNK-UNK-UNK, ...
著者Zhang, Z, Huang, Q, Tao, X.
登録日2017-07-25
公開日2018-08-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.70009851 Å)
主引用文献The unique trimeric assembly of the virulence factor HtrA fromHelicobacter pylorioccurs via N-terminal domain swapping.
J.Biol.Chem., 294, 2019
2AR9
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BU of 2ar9 by Molmil
Crystal structure of a dimeric caspase-9
分子名称: Caspase-9, D-MALATE
著者Chao, Y, Shiozaki, E.N, Srinivassula, S.M, Rigotti, D.J, Fairman, R, Shi, Y.
登録日2005-08-19
公開日2005-10-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Engineering a Dimeric Caspase-9: A Re-Evaluation of the Induced Proximity Model for Caspase Activation
PLOS BIOL., 3, 2005
5Y5F
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BU of 5y5f by Molmil
Structure of cytochrome P450nor in NO-bound state: damaged by low-dose (0.72 MGy) X-ray
分子名称: GLYCEROL, NADP nitrous oxide-forming nitric oxide reductase, NITRIC OXIDE, ...
著者Tosha, T, Nomura, T, Nishida, T, Ueno, G, Murakami, H, Yamashita, K, Hirata, K, Yamamoto, M, Ago, H, Sugimoto, H, Shiro, Y, Kubo, M.
登録日2017-08-09
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
6H9B
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1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation
分子名称: 9-methyl-3-[1-(2-methylquinolin-4-yl)ethenyl]carbazole, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Varela, P.F, Gigant, B.
登録日2018-08-03
公開日2018-12-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation.
J. Med. Chem., 62, 2019
1V6V
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Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 3(2)-alpha-L-arabinofuranosyl-xylotriose
分子名称: ENDO-1,4-BETA-D-XYLANASE, alpha-L-arabinofuranose-(1-3)-[beta-D-xylopyranose-(1-4)]beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, beta-D-xylopyranose, ...
著者Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H.
登録日2003-12-04
公開日2004-04-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86
J.Biol.Chem., 279, 2004
6CHJ
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BU of 6chj by Molmil
Wax ester synthase/diacylglycerol acyltransferase from Marinobacter aquaeolei VT8
分子名称: CHLORIDE ION, Diacylglycerol O-acyltransferase
著者Petronikolou, N, Satish, S.K.
登録日2018-02-22
公開日2018-06-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.428 Å)
主引用文献Structural and Biochemical Studies of a Biocatalyst for the Enzymatic Production of Wax Esters.
Acs Catalysis, 8, 2018
6HHF
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BU of 6hhf by Molmil
Crystal Structure of AKT1 in Complex with Covalent-Allosteric AKT Inhibitor Borussertib
分子名称: Borussertib, RAC-alpha serine/threonine-protein kinase
著者Landel, I, Weisner, J, Mueller, M.P, Scheinpflug, R, Rauh, D.
登録日2018-08-28
公開日2019-03-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib inKRAS-Mutant Pancreatic and Colorectal Cancer.
Cancer Res., 79, 2019
6BWC
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BU of 6bwc by Molmil
X-ray structure of Pen from Bacillus thuringiensis
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Polysaccharide biosynthesis protein CapD, SULFATE ION, ...
著者Delvaux, N.A, Thoden, J.B, Holden, H.M.
登録日2017-12-14
公開日2018-01-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular architectures of Pen and Pal: Key enzymes required for CMP-pseudaminic acid biosynthesis in Bacillus thuringiensis.
Protein Sci., 27, 2018
2AYO
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BU of 2ayo by Molmil
Structure of USP14 bound to ubquitin aldehyde
分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 14
著者Hu, M, Li, P, Jeffrey, P.D, Shi, Y.
登録日2005-09-07
公開日2005-10-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14.
Embo J., 24, 2005
6C0L
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BU of 6c0l by Molmil
Crystal structure of HIV-1 E138K mutant reverse transcriptase in complex with non-nucleoside inhibitor K-5a2
分子名称: 1,2-ETHANEDIOL, 4-[(4-{[4-(4-cyano-2,6-dimethylphenoxy)thieno[3,2-d]pyrimidin-2-yl]amino}piperidin-1-yl)methyl]benzene-1-sulfonamide, MAGNESIUM ION, ...
著者Yang, Y, Nguyen, L.A, Smithline, Z.B, Steitz, T.A.
登録日2018-01-01
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d]pyrimidine non-nucleoside inhibitors.
Elife, 7, 2018
5ZCW
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Structure of the Methanosarcina mazei class II CPD-photolyase in complex with intact, phosphodiester linked, CPD-lesion
分子名称: 5'-D(*AP*TP*CP*GP*GP*CP*(TTD)P*CP*GP*CP*GP*CP*AP*A)-3', 5'-D(*TP*GP*CP*GP*CP*GP*AP*AP*GP*CP*CP*GP*AP*T)-3', ACETATE ION, ...
著者Maestre-Reyna, M, Bessho, Y.
登録日2018-02-21
公開日2018-08-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Twist and turn: a revised structural view on the unpaired bubble of class II CPD photolyase in complex with damaged DNA.
IUCrJ, 5, 2018
6HMI
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Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7
分子名称: RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Campagne, S, Allain, F.H.
登録日2018-09-12
公開日2019-08-14
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural basis of a small molecule targeting RNA for a specific splicing correction.
Nat.Chem.Biol., 15, 2019
2CFS
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crystal structure of human pyridoxal 5'-phosphate phosphatase
分子名称: MAGNESIUM ION, PYRIDOXAL PHOSPHATE PHOSPHATASE
著者Kang, B.S, Cho, H.J, Kim, K.J, Kwon, O.S.
登録日2006-02-23
公開日2007-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Human Pyridoxal 5'-Phosphate Phosphatase
To be Published
2COR
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BU of 2cor by Molmil
Solution structure of the third LIM domain of particularly interesting new Cys-His protein
分子名称: PINCH protein, ZINC ION
著者Qin, X.R, Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-18
公開日2005-11-18
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the third LIM domain of particularly interesting new Cys-His protein
To be published
1Z68
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Crystal Structure Of Human Fibroblast Activation Protein alpha
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Aertgeerts, K, Levin, I, Shi, L, Prasad, G.S, Zhang, Y, Kraus, M.L, Salakian, S, Snell, G.P, Sridhar, V, Wijnands, R, Tennant, M.G.
登録日2005-03-21
公開日2005-04-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha.
J.Biol.Chem., 280, 2005
6CSV
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The structure of the Cep63-Cep152 heterotetrameric complex
分子名称: Centrosomal protein of 63 kDa,Centrosomal protein of 152 kDa
著者Lee, E, Chen, Y, Zhang, L, Kim, T.S, Ahn, J.I, Park, J.E, Lee, K.S.
登録日2018-03-21
公開日2019-03-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular architecture of a cylindrical self-assembly at human centrosomes.
Nat Commun, 10, 2019
7Y0V
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The co-crystal structure of BA.1-RBD with Fab-5549
分子名称: 5549-Fab, Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Xiao, J.Y, Zhang, Y.
登録日2022-06-06
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents.
Cell Rep, 41, 2022

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