2AR9

Crystal structure of a dimeric caspase-9

Summary for 2AR9

Entry DOI	10.2210/pdb2ar9/pdb
Descriptor	Caspase-9, D-MALATE (3 entities in total)
Functional Keywords	caspase, caspase activation, initiator caspase, cysteine protease, engineered caspase-9, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	122349.34
Authors	Chao, Y.,Shiozaki, E.N.,Srinivassula, S.M.,Rigotti, D.J.,Fairman, R.,Shi, Y. (deposition date: 2005-08-19, release date: 2005-10-11, Last modification date: 2023-08-23)
Primary citation	Chao, Y.,Shiozaki, E.N.,Srinivassula, S.M.,Rigotti, D.J.,Fairman, R.,Shi, Y. Engineering a Dimeric Caspase-9: A Re-Evaluation of the Induced Proximity Model for Caspase Activation PLOS BIOL., 3:1079-1087, 2005 Cited by PubMed: 15941357 DOI: 10.1371/journal.pbio.0030183 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation