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2AR9

Crystal structure of a dimeric caspase-9

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Caspase-9polymer27830553.84UniProt (P55211)
Pfam (PF00656)
Homo sapiens (human)
2E
(A)
D-MALATEnon-polymer134.11Chemie (MLT)
3F, G, H, I
(A, B, C, D)
waterwater18.0133Chemie (HOH)
Sequence modifications
A, B, C, D: 140 - 416 (UniProt: P55211)
PDBExternal DatabaseDetails
Met 139139initiating methionine
Ser 287Cys 287engineered mutation
Cys 402Gly 402engineered mutation
Ile 403Cys 403engineered mutation
Val 404Phe 404engineered mutation
Ser 405Asn 405engineered mutation
Met 406Phe 406engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight122215.2
Non-Polymers*Number of molecules1
Total formula weight134.1
All*Total formula weight122349.3
*Water molecules are not included.

227111

PDB entries from 2024-11-06

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