2AR9
Crystal structure of a dimeric caspase-9
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D (A, B, C, D) | Caspase-9 | polymer | 278 | 30553.8 | 4 | UniProt (P55211) Pfam (PF00656) | Homo sapiens (human) | |
2 | E (A) | D-MALATE | non-polymer | 134.1 | 1 | Chemie (MLT) | |||
3 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 140 - 416 (UniProt: P55211)
PDB | External Database | Details |
---|---|---|
Met 139 | 139 | initiating methionine |
Ser 287 | Cys 287 | engineered mutation |
Cys 402 | Gly 402 | engineered mutation |
Ile 403 | Cys 403 | engineered mutation |
Val 404 | Phe 404 | engineered mutation |
Ser 405 | Asn 405 | engineered mutation |
Met 406 | Phe 406 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 122215.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 134.1 | |
All* | Total formula weight | 122349.3 |