8R0G
 
 | | Capsid structure of Giardiavirus (GLV) CAT strain | | 分子名称: | Capsid protein | | 著者 | Wang, H, Gianluca, M, Munke, A, Hassan, M.M, Lalle, M, Okamoto, K. | | 登録日 | 2023-10-31 | | 公開日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Capsid structure of Giardiavirus (GLV) CAT strain
To Be Published
|
|
8R0F
 | | Capsid structure of Giardiavirus (GLV) HP strain | | 分子名称: | Capsid protein | | 著者 | Wang, H, Gianluca, M, Munke, A, Hassan, M.M, Lalle, M, Okamoto, K. | | 登録日 | 2023-10-31 | | 公開日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (2.14 Å) | | 主引用文献 | Capsid structure of Giardiavirus (GLV) HP strain
To Be Published
|
|
8T3O
 | | Cryo-EM structure of the TUG-891 bound FFA4-Gq complex | | 分子名称: | (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, ... | | 著者 | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | | 登録日 | 2023-06-07 | | 公開日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
|
|
8T3S
 | | Cryo-EM structure of the Butyrate bound FFA2-Gq complex | | 分子名称: | CHOLESTEROL, Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | | 登録日 | 2023-06-07 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
|
|
8SSH
 | |
8RFM
 | | Human NOQ1 enzyme in complex with NADH by serial crystallography | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Martin-Garcia, J.M, Grieco, A, Medina, M, Boneta, S, Pey, A.L. | | 登録日 | 2023-12-13 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations.
Protein Sci., 33, 2024
|
|
8RFN
 | | Human NOQ1 enzyme in its holo form by serial crystallography | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1 | | 著者 | Martin-Garcia, J.M, Grieco, A, Medina, M, Boneta, S, Pey, A.L. | | 登録日 | 2023-12-13 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations.
Protein Sci., 33, 2024
|
|
8TH3
 | |
8TH4
 | |
8QCI
 | | FCGBP D10 Assembly Segment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | | 著者 | Yeshaya, N, Fass, D. | | 登録日 | 2023-08-27 | | 公開日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | VWD domain stabilization by autocatalytic Asp-Pro cleavage.
Protein Sci., 33, 2024
|
|
8PPR
 | |
8Q5R
 | | HpARI bound to mouse IL-33 | | 分子名称: | 1,2-ETHANEDIOL, Alarmin release inhibitor, CHLORIDE ION, ... | | 著者 | Jamwal, A, Higgins, M.K. | | 登録日 | 2023-08-09 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for IL-33 recognition and its antagonism by the helminth effector protein HpARI2.
Nat Commun, 15, 2024
|
|
8TU2
 | |
8TU1
 | |
8TU0
 | |
8U5F
 | | Crystal Structure of Trypsinized Clostridium perfringens Enterotoxin | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Heat-labile enterotoxin B chain, ... | | 著者 | Kapoor, S, Ogbu, C.P, Vecchio, A.J. | | 登録日 | 2023-09-12 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Structural Basis of Clostridium perfringens Enterotoxin Activation and Oligomerization by Trypsin.
Toxins, 15, 2023
|
|
8TQE
 | | XptA2 wild type | | 分子名称: | XptA2 | | 著者 | Martin, C.L, Binshtein, E.M, Aller, S.G. | | 登録日 | 2023-08-07 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structures of the Insecticidal Toxin Complex Subunit XptA2 Highlight Roles for Flexible Domains.
Int J Mol Sci, 24, 2023
|
|
8TV0
 | | XptA2 wild type | | 分子名称: | XptA2 | | 著者 | Martin, C.L, Aller, S.G. | | 登録日 | 2023-08-17 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structures of the Insecticidal Toxin Complex Subunit XptA2 Highlight Roles for Flexible Domains.
Int J Mol Sci, 24, 2023
|
|
8TO0
 | | 48-nm repeating structure of doublets from mouse sperm flagella | | 分子名称: | Cilia- and flagella- associated protein 210, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ... | | 著者 | Chen, Z, Shiozak, M, Hass, K.M, Skinner, W, Zhao, S, Guo, C, Polacco, B.J, Yu, Z, Krogan, N.J, Kaake, R.M, Vale, R.D, Agard, D.A. | | 登録日 | 2023-08-02 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking.
Cell, 186, 2023
|
|
8U5E
 | |
8U5D
 | |
8U3B
 | | Cryo-EM structure of E. coli NarL-transcription activation complex at 3.2A | | 分子名称: | DNA (69-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Liu, B, Kompaniiets, D, Wang, D. | | 登録日 | 2023-09-07 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Structural basis for transcription activation by the nitrate-responsive regulator NarL.
Nucleic Acids Res., 52, 2024
|
|
7ACD
 | | Crystal structure of the human METTL3-METTL14 complex with compound T30 (UZH1a) | | 分子名称: | 4-[(4,4-dimethylpiperidin-1-yl)methyl]-2-oxidanyl-~{N}-[[(3~{R})-3-oxidanyl-1-[6-[(phenylmethyl)amino]pyrimidin-4-yl]piperidin-3-yl]methyl]benzamide, ACETATE ION, MAGNESIUM ION, ... | | 著者 | Bedi, R.K, Huang, D, Caflisch, A. | | 登録日 | 2020-09-10 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | METTL3 Inhibitors for Epitranscriptomic Modulation of Cellular Processes.
Chemmedchem, 16, 2021
|
|
6UNG
 | | Human CYP3A4 bound to an inhibitor | | 分子名称: | Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2S)-1-(naphthalen-1-yl)-3-{[(2R)-3-oxo-2-(phenylamino)-3-{[(pyridin-3-yl)methyl]amino}propyl]sulfanyl}propan-2-yl]carbamate | | 著者 | Sevrioukova, I.F. | | 登録日 | 2019-10-11 | | 公開日 | 2020-02-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | An increase in side-group hydrophobicity largely improves the potency of ritonavir-like inhibitors of CYP3A4.
Bioorg.Med.Chem., 28, 2020
|
|
6UNJ
 | | Human CYP3A4 bound to an inhibitor | | 分子名称: | Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2R)-1-(naphthalen-1-yl)-3-{[(2S)-1-oxo-3-phenyl-1-{[2-(pyridin-3-yl)ethyl]amino}propan-2-yl]sulfanyl}propan-2-yl]carbamate | | 著者 | Sevrioukova, I. | | 登録日 | 2019-10-12 | | 公開日 | 2020-02-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | An increase in side-group hydrophobicity largely improves the potency of ritonavir-like inhibitors of CYP3A4.
Bioorg.Med.Chem., 28, 2020
|
|
