8Q5R

HpARI bound to mouse IL-33

Summary for 8Q5R

Entry DOI	10.2210/pdb8q5r/pdb
Descriptor	Interleukin-33, Alarmin release inhibitor, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	helminth; il-33; anti-allergy; anti-inflammatory, immunosuppressant
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	2
Total formula weight	43605.67
Authors	Jamwal, A.,Higgins, M.K. (deposition date: 2023-08-09, release date: 2024-05-08, Last modification date: 2024-07-03)
Primary citation	Jamwal, A.,Colomb, F.,McSorley, H.J.,Higgins, M.K. Structural basis for IL-33 recognition and its antagonism by the helminth effector protein HpARI2. Nat Commun, 15:5226-5226, 2024 Cited by PubMed: 38890291 DOI: 10.1038/s41467-024-49550-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation