PDB: 8717 件ウェブページステータス検索Chemie searchBIRD

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5J2P	HIV-1 reverse transcriptase in complex with DNA that has incorporated EFdA-MP at the P-(post-translocation) site and a second EFdA-MP at the N-(pre-translocation) site 分子名称: 2'-deoxy-4'-ethynyl-2-fluoroadenosine 5'-(dihydrogen phosphate), DNA (27-MER), DNA (5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(6FM)P*(6FM))-3'), ... 著者 Salie, Z.L, Kirby, K.A, Sarafianos, S.G. 登録日 2016-03-29 公開日 2016-08-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Structural basis of HIV inhibition by translocation-defective RT inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA). Proc.Natl.Acad.Sci.USA, 113, 2016
5I42	Structure of HIV-1 Reverse Transcriptase in complex with a DNA aptamer, AZTTP, and CA(2+) ion 分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (38-MER), ... 著者 Das, K, Arnold, E. 登録日 2016-02-11 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. Acs Chem.Biol., 11, 2016
5HP1	STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE In COMPLEX WITH A DNA aptamer and FOSCARNET, a Pyrophosphate analog 分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, DNA (38-MER), GLYCEROL, ... 著者 Das, K, Arnold, E. 登録日 2016-01-19 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. Acs Chem.Biol., 11, 2016
5I3U	STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE N-SITE COMPLEX; CATALYTIC INCORPORATION OF AZTMP to A DNA aptamer in CRYSTAL 分子名称: DNA (39-MER), GLYCEROL, HIV-1 REVERSE TRANSCRIPTASE P51 SUBUNIT, ... 著者 Das, K, Arnold, E. 登録日 2016-02-11 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. Acs Chem.Biol., 11, 2016
5HRO	STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE In COMPLEX WITH A DNA aptamer and an Alpha-carboxy nucleoside phosphonate inhibitor (alpha-CNP) 分子名称: DNA (38-MER), HIV-1 REVERSE TRANSCRIPTASE P51 SUBUNIT, HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT, ... 著者 Das, K, Arnold, E. 登録日 2016-01-23 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. Acs Chem.Biol., 11, 2016
7TFI	Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with an open clamp 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2022-01-06 公開日 2022-11-16 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair. Elife, 11, 2022
7TFH	Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to two DNA molecules, one at the 5'-recessed end and the other at the 3'-recessed end 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2022-01-06 公開日 2022-11-16 実験手法 ELECTRON MICROSCOPY (3.09 Å) 主引用文献 Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair. Elife, 11, 2022
7TFJ	Atomic model of S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with a closed clamp ring 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2022-01-06 公開日 2022-11-16 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair. Elife, 11, 2022
5J2N	HIV-1 reverse transcriptase in complex with DNA that has incorporated EFdA-MP at the P-(post-translocation) site and dTMP at the N-(pre-translocation) site 分子名称: DNA (27-MER), DNA 5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3', MAGNESIUM ION, ... 著者 Salie, Z.L, Kirby, K.A, Sarafianos, S.G. 登録日 2016-03-29 公開日 2016-08-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.896 Å) 主引用文献 Structural basis of HIV inhibition by translocation-defective RT inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA). Proc.Natl.Acad.Sci.USA, 113, 2016
6X0N	Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin 分子名称: DNA (167-MER), Histone H2A, Histone H2B 1.1, ... 著者 Halic, M, Bilokapic, S. 登録日 2020-05-16 公開日 2020-09-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (10 Å) 主引用文献 Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin. Nature, 585, 2020
6UPL	Structure of FACT_subnucleosome complex 2 分子名称: DNA (79-mer), FACT complex subunit SPT16, FACT complex subunit SSRP1, ... 著者 Zhou, K, Tan, Y.Z, Wei, H, Liu, Y, Carragher, B, Potter, C, Luger, K. 登録日 2019-10-17 公開日 2019-12-11 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 FACT caught in the act of manipulating the nucleosome. Nature, 577, 2020
6UPK	Structure of FACT_subnucleosome complex 1 分子名称: DNA (79-mer), FACT complex subunit SPT16, FACT complex subunit SSRP1, ... 著者 Zhou, K, Tan, Y.Z, Wei, H, Liu, Y, Carragher, B, Potter, C, Luger, K. 登録日 2019-10-17 公開日 2019-12-11 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 FACT caught in the act of manipulating the nucleosome. Nature, 577, 2020
4UIH	Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to the virus before 37 degree C incubation. 分子名称: ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN NEW GUINEA-C E PROTEIN ECTODOMAIN 著者 Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe, J.E, Lok, S.-M. 登録日 2015-03-30 公開日 2015-07-15 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (20 Å) 主引用文献 Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349, 2015
6LUF	Trans-acting mutant Y290A of the central AAA+ domain of the flagellar regulatory protein FlrC 分子名称: ADENOSINE-5'-DIPHOSPHATE, Flagellar regulatory protein C 著者 Dasgupta, J, Chakraborty, S. 登録日 2020-01-27 公開日 2020-03-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Oligomerization of flagellar regulatory protein FlrC is essential for cis-mediated ATP binding while c-di-GMP prefers its monomeric state To Be Published
6LUA	Cis-mutant R349A of the central AAA+ domain of the flagellar regulatory protein FlrC 分子名称: 1,2-ETHANEDIOL, Flagellar regulatory protein C 著者 Dasgupta, J, Chakraborty, S. 登録日 2020-01-27 公開日 2020-03-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Oligomerization of flagellar regulatory protein FlrC is essential for cis-mediated ATP binding while c-di-GMP prefers its monomeric state To Be Published
5T1V	Crystal structure of Zika virus NS2B-NS3 protease in apo-form. 分子名称: NS2B-NS3 protease,NS2B-NS3 protease 著者 Nocadello, S, Light, S.H, Minasov, G, Shuvalova, L, Cardona-Correa, A.A, Ojeda, I, Vargas, J, Johnson, M.E, Lee, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2016-08-22 公開日 2016-09-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of Zika virus NS2B-NS3 protease in apo-form. To Be Published
4QHS	Crystal structure of AAA+sigma 54 activator domain of the flagellar regulatory protein FlrC of Vibrio cholerae in nucleotide free state 分子名称: 1,2-ETHANEDIOL, Flagellar regulatory protein C 著者 Dey, S, Biswas, M, Sen, U, Dasgupta, J. 登録日 2014-05-29 公開日 2014-07-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Unique ATPase site architecture triggers cis-mediated synchronized ATP binding in heptameric AAA+-ATPase domain of flagellar regulatory protein FlrC J.Biol.Chem., 290, 2015
4QHT	Crystal structure of AAA+/ sigma 54 activator domain of the flagellar regulatory protein FlrC from Vibrio cholerae in ATP analog bound state 分子名称: 1,2-ETHANEDIOL, Flagellar regulatory protein C, MAGNESIUM ION, ... 著者 Dey, S, Biswas, M, Sen, U, Dasgupta, J. 登録日 2014-05-29 公開日 2014-07-16 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.559 Å) 主引用文献 Unique ATPase site architecture triggers cis-mediated synchronized ATP binding in heptameric AAA+-ATPase domain of flagellar regulatory protein FlrC J.Biol.Chem., 290, 2015
8VAR	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA2 conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAL	Structure of the E. coli clamp loader bound to the beta clamp in a Open-DNAp/t conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAQ	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA1 conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAS	Structure of the E. coli clamp loader bound to the beta clamp in an Altered-Collar conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
1T03	HIV-1 reverse transcriptase crosslinked to tenofovir terminated template-primer (complex P) 分子名称: MAGNESIUM ION, POL polyprotein, Synthetic oligonucleotide primer, ... 著者 Tuske, S, Sarafianos, S.G, Ding, J, Arnold, E. 登録日 2004-04-07 公開日 2004-05-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir Nat.Struct.Mol.Biol., 11, 2004
1T05	HIV-1 reverse transcriptase crosslinked to template-primer with tenofovir-diphosphate bound as the incoming nucleotide substrate 分子名称: GLYCEROL, MAGNESIUM ION, POL polyprotein, ... 著者 Tuske, S, Sarafianos, S.G, Ding, J, Arnold, E. 登録日 2004-04-07 公開日 2004-05-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir Nat.Struct.Mol.Biol., 11, 2004
3MRI	Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide G4M-V5W variant 分子名称: 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Reiser, J.-B, Le Gorrec, M, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. 登録日 2010-04-29 公開日 2011-05-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide G4M-V5W variant To be Published

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