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7TFI

Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with an open clamp

Summary for 7TFI
Entry DOI10.2210/pdb7tfi/pdb
EMDB information25872 25873 25874 25875 25876
DescriptorReplication factor C subunit 1, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (11 entities in total)
Functional Keywordsdna replication, dna damage repair, rfc loader, pcna clamp, dna polymerase processivity factor, dna binding protein-dna complex, dna binding protein/dna
Biological sourceSaccharomyces cerevisiae (baker's yeast)
More
Total number of polymer chains10
Total formula weight358410.78
Authors
Zheng, F.,Georgescu, R.,Yao, Y.N.,O'Donnell, M.E.,Li, H. (deposition date: 2022-01-06, release date: 2022-11-16)
Primary citationZheng, F.,Georgescu, R.,Yao, N.Y.,Li, H.,O'Donnell, M.E.
Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11:-, 2022
Cited by
PubMed: 35829698
DOI: 10.7554/eLife.77469
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.41 Å)
Structure validation

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