PDB: 1731 件ウェブページステータス検索Chemie searchBIRD

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3M4V	Crystal structure of the A330P mutant of cytochrome P450 BM3 分子名称: Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Yang, W, Whitehouse, C.J.C, Bell, S.G, Bartlam, M, Wong, L.L, Rao, Z. 登録日 2010-03-12 公開日 2011-03-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for the properties of two single-site proline mutants of CYP102A1 (P450BM3) Chembiochem, 11, 2010
3WSP	Crystal Structure of P450BM3 with N-perfluorononanoyl-L-tryptophan 分子名称: Bifunctional P-450/NADPH-P450 reductase, DIMETHYL SULFOXIDE, N-(2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-heptadecafluorononanoyl)-L-tryptophan, ... 著者 Cong, Z, Shoji, O, Kasai, C, Sugimoto, H, Shiro, Y, Watanabe, Y. 登録日 2014-03-20 公開日 2014-11-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Activation of Wild-type Cytochrome P450BM3 by the Next Generation of Decoy Molecules: Enhanced Hydroxylation of Gaseous Alkanes and Crystallographic Evidence. ACS CATALYSIS, 5, 2015
2IJ7	Structure of Mycobacterium tuberculosis CYP121 in complex with the antifungal drug fluconazole 分子名称: 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE 著者 Roujeinikova, A, Leys, D. 登録日 2006-09-29 公開日 2006-11-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode. J.Biol.Chem., 281, 2006
5D3U	Crystal structure of the 5-selective H176F mutant of Cytochrome TxtE 分子名称: CHLORIDE ION, GLYCEROL, P450-like protein, ... 著者 Cahn, J.K.B, Dodani, S.C, Arnold, F.H. 登録日 2015-08-06 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models. Nat.Chem., 8, 2016
5D40	Crystal structure of the 5-selective H176Y mutant of Cytochrome TxtE 分子名称: CHLORIDE ION, GLYCEROL, P450-like protein, ... 著者 Cahn, J.K.B, Dodani, S.C, Arnold, F.H. 登録日 2015-08-06 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models. Nat.Chem., 8, 2016
5EM4	Structure of CYP2B4 F244W in a ligand free conformation 分子名称: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE 著者 Shah, M.B, Stout, C.D, Halpert, J.R. 登録日 2015-11-05 公開日 2016-03-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations. Biochemistry, 55, 2016
5A1P	Crystal structure of cytochrome P450 3A4 bound to progesterone and citrate 分子名称: CITRIC ACID, CYTOCHROME P450 3A4, PROGESTERONE, ... 著者 Sevrioukova, I, Poulos, T. 登録日 2015-05-04 公開日 2015-06-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Anion-Dependent Stimulation of Cyp3A4 Monooxygenase. Biochemistry, 54, 2015
8DMG	CYP102A1 in Closed Conformation 分子名称: 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional cytochrome P450/NADPH--P450 reductase, FLAVIN MONONUCLEOTIDE, ... 著者 Su, M, Xu, H. 登録日 2022-07-08 公開日 2023-07-19 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Insight into the conformational dynamics of cytochrome P450 CYP102A1 enzyme using Cryo-EM To Be Published
1N97	Crystal Structure of CYP175A1 from Thermus thermophillus strain HB27 分子名称: 1,2-ETHANEDIOL, CYP175A1, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Yano, J.K, Blasco, F, Li, H, Schmid, R.D, Henne, A, Poulos, T.L. 登録日 2002-11-22 公開日 2003-02-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Preliminary Characterization and Crystal Structure of a Thermostable Cytochrome P450 from Thermus thermophilus J.Biol.Chem., 278, 2003
4HGF	Crystal structure of P450 BM3 5F5K heme domain variant complexed with styrene 分子名称: Bifunctional P-450/NADPH-P450 reductase, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Shehzad, A, Panneerselvam, S, Bocola, M, Mueller-Dieckmann, J, Wilmanns, M, Schwaneberg, U. 登録日 2012-10-08 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 P450 BM3 crystal structures reveal the role of the charged surface residue Lys/Arg184 in inversion of enantioselective styrene epoxidation. Chem.Commun.(Camb.), 49, 2013
4HGH	Crystal structure of P450 BM3 5F5 heme domain variant complexed with styrene (dataset I) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450/NADPH-P450 reductase, DI(HYDROXYETHYL)ETHER, ... 著者 Shehzad, A, Panneerselvam, S, Bocola, M, Mueller-Dieckmann, J, Wilmanns, M, Schwaneberg, U. 登録日 2012-10-08 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 P450 BM3 crystal structures reveal the role of the charged surface residue Lys/Arg184 in inversion of enantioselective styrene epoxidation. Chem.Commun.(Camb.), 49, 2013
4HGG	Crystal structure of P450 BM3 5F5R heme domain variant complexed with styrene 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450/NADPH-P450 reductase, GLYCEROL, ... 著者 Shehzad, A, Panneerselvam, S, Bocola, M, Mueller-Dieckmann, J, Wilmanns, M, Schwaneberg, U. 登録日 2012-10-08 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 P450 BM3 crystal structures reveal the role of the charged surface residue Lys/Arg184 in inversion of enantioselective styrene epoxidation. Chem.Commun.(Camb.), 49, 2013
4HGI	Crystal structure of P450 BM3 5F5 heme domain variant complexed with styrene (dataset II) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450/NADPH-P450 reductase, DI(HYDROXYETHYL)ETHER, ... 著者 Shehzad, A, Panneerselvam, S, Bocola, M, Mueller-Dieckmann, J, Wilmanns, M, Schwaneberg, U. 登録日 2012-10-08 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 P450 BM3 crystal structures reveal the role of the charged surface residue Lys/Arg184 in inversion of enantioselective styrene epoxidation. Chem.Commun.(Camb.), 49, 2013
4HGJ	Crystal structure of P450 BM3 5F5 heme domain variant 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450/NADPH-P450 reductase, GLYCEROL, ... 著者 Shehzad, A, Panneerselvam, S, Bocola, M, Mueller-Dieckmann, J, Wilmanns, M, Schwaneberg, U. 登録日 2012-10-08 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 P450 BM3 crystal structures reveal the role of the charged surface residue Lys/Arg184 in inversion of enantioselective styrene epoxidation. Chem.Commun.(Camb.), 49, 2013
5KYO	Crystal Structure of CYP101J2 分子名称: CYP101J2, PROTOPORPHYRIN IX CONTAINING FE 著者 Unterweger, B, Drinkwater, N, Dumsday, G.J, McGowan, S. 登録日 2016-07-22 公開日 2017-01-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystal structure of cytochrome P450 monooxygenase CYP101J2 from Sphingobium yanoikuyae strain B2. Proteins, 85, 2017
1ZOA	Crystal Structure Of A328V Mutant Of The Heme Domain Of P450Bm-3 With N-Palmitoylglycine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450:NADPH-P450 reductase, GLYCEROL, ... 著者 Hegda, A, Chen, B, Haines, D.C, Bondlela, M, Mullin, D, Graham, S.E, Tomchick, D.R, Machius, M, Peterson, J.A. 登録日 2005-05-12 公開日 2006-08-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 A single active-site mutation of P450BM-3 dramatically enhances substrate binding and rate of product formation. Biochemistry, 50, 2011
1ZO4	Crystal Structure Of A328S Mutant Of The Heme Domain Of P450BM-3 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450:NADPH-P450 reductase, GLYCEROL, ... 著者 Hegda, A, Chen, B, Haines, D.C, Bondlela, M, Mullin, D, Graham, S.E, Tomchick, D.R, Machius, M, Peterson, J.A. 登録日 2005-05-12 公開日 2006-08-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 A single active-site mutation of P450BM-3 dramatically enhances substrate binding and rate of product formation. Biochemistry, 50, 2011
2RFC	Ligand bound (4-phenylimidazole) Crystal Structure of a Cytochrome P450 from the Thermoacidophilic Archaeon Picrophilus Torridus 分子名称: 4-PHENYL-1H-IMIDAZOLE, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Ho, W.W, Li, H, Poulos, T.L, Nishida, C.R, Ortiz de Montellano, P.R. 登録日 2007-09-28 公開日 2008-01-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal Structure and Properties of CYP231A2 from the Thermoacidophilic Archaeon Picrophilus torridus. Biochemistry, 47, 2008
3EQM	Crystal structure of human placental aromatase cytochrome P450 in complex with androstenedione 分子名称: 4-ANDROSTENE-3-17-DIONE, Cytochrome P450 19A1, PHOSPHATE ION, ... 著者 Ghosh, D. 登録日 2008-10-01 公開日 2008-12-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for androgen specificity and oestrogen synthesis in human aromatase. Nature, 457, 2009
4LXJ	Saccharomyces cerevisiae lanosterol 14-alpha demethylase with lanosterol bound 分子名称: LANOSTEROL, Lanosterol 14-alpha demethylase, OXYGEN MOLECULE, ... 著者 Monk, B.C, Tomasiak, T.M, Keniya, M.V, Huschmann, F.U, Tyndall, J.D.A, O'Connell III, J.D, Cannon, R.D, McDonald, J, Rodriguez, A, Finer-Moore, J, Stroud, R.M. 登録日 2013-07-29 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer. Proc.Natl.Acad.Sci.USA, 111, 2014
6HN8	Structure of BM3 heme domain in complex with troglitazone 分子名称: (5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Jeffreys, L, Munro, A.W.M, Leys, D. 登録日 2018-09-14 公開日 2019-10-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.997 Å) 主引用文献 Oxidation of antidiabetic compounds by cytochrome P450 BM3 To be published
8AMO	Crystal structure of M. tuberculosis CYP143 分子名称: CHLORIDE ION, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Bukhdruker, S, Varaksa, T, Grudo, A, Marin, E, Kapranov, I, Shevtsov, M, Gilep, A, Strushkevich, N, Borshchevskiy, V. 登録日 2022-08-03 公開日 2023-02-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural insights into 3Fe-4S ferredoxins diversity in M. tuberculosis highlighted by a first redox complex with P450. Front Mol Biosci, 9, 2022
8AMQ	Crystal structure of the complex CYP143-FdxE from M. tuberculosis 分子名称: FE3-S4 CLUSTER, NICKEL (II) ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Bukhdruker, S, Varaksa, T, Smolskaya, S, Marin, E, Kapranov, I, Kovalev, K, Gilep, A, Strushkevich, N, Borshchevskiy, V. 登録日 2022-08-03 公開日 2023-02-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural insights into 3Fe-4S ferredoxins diversity in M. tuberculosis highlighted by a first redox complex with P450. Front Mol Biosci, 9, 2022
3OIA	Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC1-C8GluEtg-Bio 分子名称: Camphor 5-monooxygenase, N-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}-N'-(8-{[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-ylcarbonyl]amino}octyl)pentanediamide, POTASSIUM ION, ... 著者 Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B. 登録日 2010-08-18 公開日 2010-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC1-C8GluEtg-Bio To be Published
3OL5	Crystal Structure of Cytochrome P450cam crystallized with a tethered substrate analog 3OH-AdaC1-C8-Dans 分子名称: (1R,3S,5R,7S)-N-[8-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)octyl]-3-hydroxytricyclo[3.3.1.1~3,7~]decane-1-carboxamide, Camphor 5-monooxygenase, POTASSIUM ION, ... 著者 Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B. 登録日 2010-08-25 公開日 2010-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structure of Cytochrome P450cam crystallized with a tethered substrate analog 3OH-AdaC1-C8-Dans To be Published

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