5D3U

Crystal structure of the 5-selective H176F mutant of Cytochrome TxtE

Summary for 5D3U

Entry DOI	10.2210/pdb5d3u/pdb
Related	5D40
Descriptor	P450-like protein, PROTOPORPHYRIN IX CONTAINING FE, TRYPTOPHAN, ... (6 entities in total)
Functional Keywords	cytochrome, p450, heme, regioselectivity, f/g loop, oxidoreductase
Biological source	Streptomyces scabies (strain 87.22)
Total number of polymer chains	2
Total formula weight	96150.06
Authors	Cahn, J.K.B.,Dodani, S.C.,Arnold, F.H. (deposition date: 2015-08-06, release date: 2016-06-22, Last modification date: 2023-09-27)
Primary citation	Dodani, S.C.,Kiss, G.,Cahn, J.K.,Su, Y.,Pande, V.S.,Arnold, F.H. Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models. Nat.Chem., 8:419-425, 2016 Cited by PubMed: 27102675 DOI: 10.1038/nchem.2474 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation