Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
B | 0004497 | molecular_function | monooxygenase activity |
B | 0005506 | molecular_function | iron ion binding |
B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
B | 0020037 | molecular_function | heme binding |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 22 |
Details | binding site for residue HEM A 501 |
Chain | Residue |
A | ARG59 |
A | SER254 |
A | THR296 |
A | ARG298 |
A | SER349 |
A | GLY351 |
A | VAL354 |
A | HIS355 |
A | CYS357 |
A | ALA359 |
A | ILE363 |
A | VAL87 |
A | TRP502 |
A | HOH688 |
A | HOH787 |
A | MET88 |
A | HIS95 |
A | ARG99 |
A | PHE155 |
A | ALA245 |
A | THR250 |
A | THR251 |
site_id | AC2 |
Number of Residues | 11 |
Details | binding site for residue TRP A 502 |
Chain | Residue |
A | ARG59 |
A | MET88 |
A | TYR89 |
A | PHE176 |
A | ASN293 |
A | THR296 |
A | TRP297 |
A | PHE395 |
A | HEM501 |
A | HOH664 |
A | HOH671 |
site_id | AC3 |
Number of Residues | 9 |
Details | binding site for residue GOL A 503 |
Chain | Residue |
A | ARG264 |
A | PRO266 |
A | ARG267 |
A | HOH658 |
B | ASP15 |
B | TYR289 |
B | ARG326 |
B | GOL503 |
B | HOH994 |
site_id | AC4 |
Number of Residues | 22 |
Details | binding site for residue HEM B 501 |
Chain | Residue |
B | ARG59 |
B | VAL87 |
B | MET88 |
B | HIS95 |
B | ARG99 |
B | PHE155 |
B | ALA245 |
B | THR250 |
B | THR251 |
B | SER254 |
B | THR296 |
B | ARG298 |
B | SER349 |
B | GLY351 |
B | VAL354 |
B | HIS355 |
B | CYS357 |
B | ALA359 |
B | TRP502 |
B | HOH622 |
B | HOH671 |
B | HOH773 |
site_id | AC5 |
Number of Residues | 12 |
Details | binding site for residue TRP B 502 |
Chain | Residue |
B | ARG59 |
B | MET88 |
B | TYR89 |
B | PHE176 |
B | ASN293 |
B | THR296 |
B | TRP297 |
B | PHE395 |
B | HEM501 |
B | HOH622 |
B | HOH686 |
B | HOH698 |
site_id | AC6 |
Number of Residues | 12 |
Details | binding site for residue GOL B 503 |
Chain | Residue |
A | ARG267 |
A | GOL503 |
B | PRO14 |
B | TYR17 |
B | ARG264 |
B | TYR289 |
B | ASN290 |
B | ARG326 |
B | TRP389 |
B | ARG396 |
B | CL504 |
B | HOH689 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue CL B 504 |
Chain | Residue |
B | ARG264 |
B | TYR289 |
B | GOL503 |
B | HOH788 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGqGVHACLA |
Chain | Residue | Details |
A | PHE350-ALA359 | |