5A1P
Crystal structure of cytochrome P450 3A4 bound to progesterone and citrate
Summary for 5A1P
| Entry DOI | 10.2210/pdb5a1p/pdb |
| Related | 5A1R |
| Descriptor | CYTOCHROME P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, PROGESTERONE, ... (5 entities in total) |
| Functional Keywords | oxidoreductase, cytochrome p450 3a4, cyp3a4, monooxygenase, progesterone, citrate |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Endoplasmic reticulum membrane; Single-pass membrane protein: P08684 |
| Total number of polymer chains | 1 |
| Total formula weight | 56880.89 |
| Authors | Sevrioukova, I.,Poulos, T. (deposition date: 2015-05-04, release date: 2015-06-24, Last modification date: 2024-01-10) |
| Primary citation | Sevrioukova, I.F.,Poulos, T.L. Anion-Dependent Stimulation of Cyp3A4 Monooxygenase. Biochemistry, 54:4083-, 2015 Cited by PubMed: 26066995DOI: 10.1021/ACS.BIOCHEM.5B00510 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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