PDB: 1409 件ウェブページステータス検索Chemie searchBIRD

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5IMK	Nanobody targeting human Vsig4 in Spacegroup C2 分子名称: Nanobody, V-set and immunoglobulin domain-containing protein 4 著者 Wen, Y. 登録日 2016-03-06 公開日 2017-01-11 最終更新日 2017-07-05 実験手法 X-RAY DIFFRACTION (1.227 Å) 主引用文献 Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity Immunobiology, 222, 2017
5IMO	Nanobody targeting mouse Vsig4 in Spacegroup P3221 分子名称: Nanobody, Protein Vsig4 著者 Wen, Y, Zheng, F. 登録日 2016-03-06 公開日 2017-01-11 最終更新日 2017-07-05 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity Immunobiology, 222, 2017
5IR3	Crystal structure of the recombinant highest fibrillogenic natural mutant (obtained from patient AR) derived from lambda 6 light chain variable domain 分子名称: ACETATE ION, Ig lambda chain V-VI region AR 著者 Hernandez-Santoyo, A, Rodriguez-Romero, A. 登録日 2016-03-11 公開日 2017-06-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Stabilizing an amyloidogenic lambda 6 light chain variable domain. FEBS J., 284, 2017
5IUS	Crystal structure of human PD-L1 in complex with high affinity PD-1 mutant 分子名称: CHLORIDE ION, Programmed cell death 1 ligand 1, Programmed cell death protein 1 著者 Pascolutti, R, Sun, X, Kao, J, Maute, R, Ring, A.M, Bowman, G.R, Kruse, A.C. 登録日 2016-03-18 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.889 Å) 主引用文献 Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant. Structure, 24, 2016
5J06	Structure of the immune receptor CD33 in complex with 3'-sialyllactose 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33, ... 著者 Dodd, R.B. 登録日 2016-03-27 公開日 2017-04-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 STRUCTURE OF LIGAND BOUND CD33 RECEPTOR ASSOCIATED WITH ALZHEIMER'S DISEASE To Be Published
5J0B	Structure of the immune receptor CD33 in complex with 6'-sialyllactose 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33, ... 著者 Dodd, R.B. 登録日 2016-03-28 公開日 2017-04-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 STRUCTURE OF LIGAND BOUND CD33 RECEPTOR ASSOCIATED WITH ALZHEIMER'S DISEASE To Be Published
5J89	Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor 分子名称: 1,2-ETHANEDIOL, N-{2-[({2-methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]pyridin-3-yl}methyl)amino]ethyl}acetamide, Programmed cell death 1 ligand 1 著者 Zak, K.M, Grudnik, P, Guzik, K, Zieba, B.J, Musielak, B, Doemling, P, Dubin, G, Holak, T.A. 登録日 2016-04-07 公開日 2016-04-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1). Oncotarget, 7, 2016
5J8O	Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor 分子名称: (2R)-1-({3-bromo-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl}methyl)piperidine-2-carboxylic acid, Programmed cell death 1 ligand 1 著者 Zak, K.M, Grudnik, P, Guzik, K, Zieba, B.J, Musielak, B, Doemling, P, Dubin, G, Holak, T.A. 登録日 2016-04-08 公開日 2016-04-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1). Oncotarget, 7, 2016
5JDR	Structure of PD-L1 分子名称: Programmed cell death 1 ligand 1 著者 Zhou, A, Wei, H. 登録日 2016-04-17 公開日 2017-04-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of a novel PD-L1 nanobody for immune checkpoint blockade. Cell Discov, 3, 2017
5JDS	Crystal structure of PD-L1 complexed with a nanobody at 1.7 Angstron resolution 分子名称: CHLORIDE ION, Nanobody, Programmed cell death 1 ligand 1, ... 著者 Zhou, A, Wei, H. 登録日 2016-04-17 公開日 2017-04-12 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis of a novel PD-L1 nanobody for immune checkpoint blockade. Cell Discov, 3, 2017
5JXE	Human PD-1 ectodomain complexed with Pembrolizumab Fab 分子名称: Pembrolizumab Fab heavy chain, Pembrolizumab Fab light chain, Programmed cell death protein 1 著者 Na, Z, Bharath, S.R, Song, H. 登録日 2016-05-13 公開日 2016-08-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for blocking PD-1-mediated immune suppression by therapeutic antibody pembrolizumab. Cell Res., 27, 2017
5L8K	Aurora-A kinase domain in complex with vNAR-D01 (crystal form 2) 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... 著者 Burgess, S.G, Bayliss, R. 登録日 2016-06-08 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain. Open Biology, 6, 2016
5L8J	Aurora-A kinase domain in complex with vNAR-D01 S93R 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... 著者 Burgess, S.G, Bayliss, R. 登録日 2016-06-08 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain. Open Biology, 6, 2016
5L8L	Aurora-A kinase domain in complex with vNAR-D01 (crystal form 1) 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... 著者 Burgess, S.G, Bayliss, R. 登録日 2016-06-08 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain. Open Biology, 6, 2016
5B8C	High resolution structure of the human PD-1 in complex with pembrolizumab Fv 分子名称: Pembrolizumab heavy chain variable region (PemVH), Pembrolizumab light chain variable region (PemVL), Programmed cell death protein 1 著者 Horita, S, Shimamura, T, Iwata, S, Nomura, N. 登録日 2016-06-14 公開日 2016-10-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.146 Å) 主引用文献 High-resolution crystal structure of the therapeutic antibody pembrolizumab bound to the human PD-1 Sci Rep, 6, 2016
5GGS	PD-1 in complex with pembrolizumab Fab 分子名称: Programmed cell death protein 1, heavy chain, light chain 著者 Heo, Y.S. 登録日 2016-06-16 公開日 2016-11-09 最終更新日 2016-11-16 実験手法 X-RAY DIFFRACTION (1.997 Å) 主引用文献 Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
5GGV	CTLA-4 in complex with tremelimumab Fab 分子名称: Cytotoxic T-lymphocyte protein 4, heavy chain, light chain 著者 Heo, Y.S. 登録日 2016-06-16 公開日 2016-11-09 最終更新日 2016-11-16 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
5GGT	PD-L1 in complex with BMS-936559 Fab 分子名称: IGK@ protein, IgG H chain, Programmed cell death 1 ligand 1 著者 Heo, Y.S. 登録日 2016-06-16 公開日 2016-11-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
5GGR	PD-1 in complex with nivolumab Fab 分子名称: Programmed cell death protein 1, heavy chain, light chain 著者 Heo, Y.S. 登録日 2016-06-16 公開日 2016-11-09 最終更新日 2016-11-16 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
5KSB	T15-DQ8.5-glia-gamma1 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DQ8.5-glia-gamma1 peptide, ... 著者 Petersen, J, Rossjohn, J, Reid, H.H. 登録日 2016-07-08 公開日 2016-09-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution. Structure, 24, 2016
5KS9	Bel502-DQ8-glia-alpha1 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bel502 TCR alpha TRAV20*01, Bel502 TCR beta TRBV9*01, ... 著者 Petersen, J, Rossjohn, J, Reid, H.H. 登録日 2016-07-08 公開日 2016-09-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution. Structure, 24, 2016
5KSA	Bel602-DQ8.5-glia-gamma1 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bel602 alpha TRAV20*01, Bel602 beta TRBV9*01, ... 著者 Petersen, J, Rossjohn, J, Reid, H.H. 登録日 2016-07-08 公開日 2016-09-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution. Structure, 24, 2016
5GRJ	Crystal structure of human PD-L1 with monoclonal antibody avelumab 分子名称: Programmed cell death 1 ligand 1, avelumab H chain, avelumab L chain 著者 Liu, K, Tan, S, Chai, Y, Chen, D, Song, H, Zhang, C.W.-H, Shi, Y, Liu, J, Tan, W, Lyu, J, Gao, S, Yan, J, Qi, J, Gao, G.F. 登録日 2016-08-11 公開日 2016-11-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.206 Å) 主引用文献 Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy. Cell Res., 27, 2017
5M00	Crystal structure of murine P14 TCR complex with H-2Db and Y4A, modified gp33 peptide from LCMV 分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... 著者 Achour, A, Sandalova, T, Sun, R, Han, X. 登録日 2016-10-03 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Thernary complexes of TCR P14 give insights into the mechanisms behind reestablishment of CTL responses against a viral escape mutant To Be Published
5M01	Crystal structure of murine P14 TCR/ H-2Db complex with PA, modified gp33 peptide from LCMV 分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ... 著者 Achour, A, Sandalova, T, Sun, R, Han, X. 登録日 2016-10-03 公開日 2017-10-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Thernary complexes of TCR P14 give insights into the mechanisms behind reestablishment of CTL responses against a viral escape mutant To Be Published

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