PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4S3P	Amylomaltase MalQ from Escherichia coli, apo structure 分子名称: 4-alpha-glucanotransferase 著者 Weiss, S.C, Schiefner, A. 登録日 2015-03-26 公開日 2015-07-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Basis for the Interconversion of Maltodextrins by MalQ, the Amylomaltase of Escherichia coli. J.Biol.Chem., 290, 2015
4RWL	Crystal structure of FGFR1 (C488A, C584C) in complex with 6-(7-((1-aminocyclopropyl) methoxy)-6-methoxyquinolin-4-yloxy)-N-methyl-1-naphthamide (E3810) 分子名称: 6-({7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-N-methylnaphthalene-1-carboxamide, Fibroblast growth factor receptor 1, SULFATE ION 著者 Sohl, C.D, Anderson, K.S. 登録日 2014-12-04 公開日 2015-04-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.193 Å) 主引用文献 Illuminating the Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance for the FGFR1 Gatekeeper Mutation: The Achilles' Heel of Targeted Therapy. Acs Chem.Biol., 10, 2015
4QG7	S.aureus TMK in complex with a potent inhibitor compound 18, 2-(3-CHLOROPHENOXY)-3-METHOXY-4-{[(3S)-3-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)PIPERIDIN-1-YL]METHYL}BENZOIC ACID 分子名称: 2-(3-chlorophenoxy)-3-methoxy-4-{[(3S)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)piperidin-1-yl]methyl}benzoic acid, Thymidylate kinase 著者 Olivier, N.B. 登録日 2014-05-22 公開日 2014-06-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Antibacterial inhibitors of gram-positive thymidylate kinase: structure-activity relationships and chiral preference of a new hydrophobic binding region. J.Med.Chem., 57, 2014
4Q2N	INADL PDZ3 in Complex with a Phage-Derived Peptide 分子名称: 1,2-ETHANEDIOL, InaD-like protein 著者 Appleton, B.A, Wiesmann, C. 登録日 2014-04-09 公開日 2014-09-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A structural portrait of the PDZ domain family. J.Mol.Biol., 426, 2014
4Q2X	Crystal structure of Arginyl-tRNA synthetase complexed with L-canavanine 分子名称: Arginine--tRNA ligase, cytoplasmic, L-CANAVANINE 著者 Kim, H.S, Jo, C.H, Cha, S.Y, Han, A.R, Hwang, K.Y. 登録日 2014-04-10 公開日 2014-07-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.798 Å) 主引用文献 The crystal structure of arginyl-tRNA synthetase from Homo sapiens Febs Lett., 588, 2014
3FAT	X-ray structure of iGluR4 flip ligand-binding core (S1S2) in complex with (S)-AMPA at 1.90A resolution 分子名称: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, ACETIC ACID, GLYCEROL, ... 著者 Kasper, C, Frydenvang, K, Naur, P, Gajhede, M, Kastrup, J.S. 登録日 2008-11-18 公開日 2008-12-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4 Febs Lett., 582, 2008
4Q5I	Crystal structure of a T151A mutant of the E. coli FeoB G-domain 分子名称: Ferrous iron transport protein B, SULFATE ION 著者 Jormakka, M, Guilfoyle, A.P, Deshpande, C.N, Maher, M. 登録日 2014-04-17 公開日 2015-04-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Exploring the correlation between the sequence composition of the nucleotide binding G5 loop of the FeoB GTPase domain (NFeoB) and intrinsic rate of GDP release. Biosci.Rep., 34, 2014
3FE7	Crystal Structure of HdmX bound to the p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-Trp-Glu-Ac3c-Leu-NH2 at 1.35A 分子名称: Mdm4 protein, p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-Trp-Glu-Ac3c-Leu-NH2 著者 Kallen, J. 登録日 2008-11-28 公開日 2009-01-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes J.Biol.Chem., 284, 2009
4Q73	Crystal Structure of Bradyrhizobium japonicum Proline Utilization A (PutA) Mutant D778Y 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Proline dehydrogenase, ... 著者 Tanner, J.J, Luo, M, Pemberton, T.A. 登録日 2014-04-23 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Kinetic and Structural Characterization of Tunnel-Perturbing Mutants in Bradyrhizobium japonicum Proline Utilization A. Biochemistry, 53, 2014
4Q9L	P-glycoprotein cocrystallised with QZ-Phe 分子名称: (30F)F(30F)F(30F)F Peptide, Multidrug resistance protein 1A 著者 McGrath, A.P, Szewczyk, P, Chang, G. 登録日 2014-05-01 公開日 2015-03-04 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein. Acta Crystallogr.,Sect.D, 71, 2015
3FF8	Structure of NK cell receptor KLRG1 bound to E-cadherin 分子名称: CALCIUM ION, Epithelial cadherin, Killer cell lectin-like receptor subfamily G member 1 著者 Li, Y, Mariuzza, R.A. 登録日 2008-12-02 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity, 31, 2009
4Q8F	Human DNA polymerase eta extending primer immediately after a phenanthriplatin adducted G 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, 5'-D(*AP*GP*TP*GP*TP*GP*AP*C)-3', 5'-D(*CP*AP*TP*CP*GP*TP*CP*AP*CP*AP*CP*T)-3', ... 著者 Gregory, M.T, Yang, W. 登録日 2014-04-26 公開日 2014-07-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.797 Å) 主引用文献 Structural and mechanistic studies of polymerase eta bypass of phenanthriplatin DNA damage. Proc.Natl.Acad.Sci.USA, 111, 2014
3FGT	Two chain form of the 66.3 kDa protein from mouse lacking the linker peptide 分子名称: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Lakomek, K, Dickmanns, A, Ficner, R. 登録日 2008-12-08 公開日 2009-09-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography Bmc Struct.Biol., 9, 2009
4QAE	Crystal structure of an engineered lipocalin (Anticalin) in complex with human hepcidin 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Hepcidin, ... 著者 Giese, T, Skerra, A. 登録日 2014-05-04 公開日 2015-05-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of a hepcidin-binding anticalin in complex with its peptide ligand To be Published
3F8W	Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase in complex with adenosine 分子名称: ADENOSINE, DIMETHYL SULFOXIDE, Purine-nucleoside phosphorylase, ... 著者 Pereira, H.M, Rezende, M.M, Garratt, R.C, Oliva, G. 登録日 2008-11-13 公開日 2009-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni. Acta Crystallogr.,Sect.D, 66, 2010
3F9R	Crystal Structure of Trypanosoma Brucei phosphomannosemutase, TB.10.700.370 分子名称: MAGNESIUM ION, Phosphomannomutase, SULFATE ION 著者 Wernimont, A.K, Lam, A, Ali, A, Lin, Y.H, Guther, L, Shamshad, A, MacKenzie, F, Bandini, G, Kozieradzki, I, Cossar, D, Zhao, Y, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Ferguson, M.A.J, Hui, R, Qiu, W, Structural Genomics Consortium (SGC) 登録日 2008-11-14 公開日 2009-03-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structure of Trypanosoma Brucei phosphomannosemutase, TB.10.700.370 To be Published
3FM9	Analysis of the Structural Determinants Underlying Discrimination between Substrate and Solvent in beta-Phosphoglucomutase Catalysis 分子名称: Beta-phosphoglucomutase, MAGNESIUM ION 著者 Finci, L, Lahiri, S, Peisach, E, Allen, K.N. 登録日 2008-12-19 公開日 2009-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Analysis of the structural determinants underlying discrimination between substrate and solvent in beta-phosphoglucomutase catalysis. Biochemistry, 48, 2009
4QGH	S.aureus TMK in complex with potent inhibitor compound 47 分子名称: 2-(3-chlorophenoxy)-3-fluoro-4-{(1S)-3-methyl-1-[(3S)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)piperidin-1-yl]butyl}benzoic acid, Thymidylate kinase 著者 Olivier, N.B. 登録日 2014-05-22 公開日 2014-06-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Antibacterial inhibitors of gram-positive thymidylate kinase: structure-activity relationships and chiral preference of a new hydrophobic binding region. J.Med.Chem., 57, 2014
3FDS	Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase IV, ... 著者 Ling, H. 登録日 2008-11-26 公開日 2009-01-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA Mol.Microbiol., 71, 2009
4QHO	Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with CCO10 分子名称: Alpha-ketoglutarate-dependent dioxygenase FTO, N-{[3-hydroxy-6-(naphthalen-1-yl)pyridin-2-yl]carbonyl}glycine, ZINC ION 著者 Aik, W.S, Clunie-O'Connor, C, McDonough, M.A, Schofield, C.J. 登録日 2014-05-28 公開日 2015-06-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors. J.Med.Chem., 64, 2021
3FFK	Crystal structure of human Gelsolin domains G1-G3 bound to Actin 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, actin, ... 著者 Chumnarnsilpa, S, Robinson, R.C, Burtnick, L.D. 登録日 2008-12-03 公開日 2009-10-06 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin. Proc.Natl.Acad.Sci.USA, 106, 2009
4QMD	Crystal structure of human envoplakin plakin repeat domain 分子名称: Envoplakin 著者 Mohammed, F, Al-Jassar, C, White, S.A, Fogl, C, Jeeves, M, Knowles, T.J, Odinstova, E, Rodriguez-Zamora, P, Overduin, M, Chidgey, M. 登録日 2014-06-16 公開日 2015-07-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin. Nat Commun, 7, 2016
3FEG	Crystal structure of human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide 分子名称: (2S)-2-[4'-({dimethyl[2-(phosphonooxy)ethyl]ammonio}acetyl)biphenyl-4-yl]-2-hydroxy-4,4-dimethylmorpholin-4-ium, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Hong, B.S, Tempel, W, Rabeh, W.M, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H.W, Structural Genomics Consortium (SGC) 登録日 2008-11-29 公開日 2008-12-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.302 Å) 主引用文献 Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity. J.Biol.Chem., 285, 2010
4QNM	CRYSTAL STRUCTURE of PSPF(1-265) E108Q MUTANT 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Psp operon transcriptional activator 著者 Darbari, V.C, Lawton, E, Lu, D, Burrows, P.C, Wiesler, S, Joly, N, Zhang, N, Zhang, X, Buck, M. 登録日 2014-06-18 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.628 Å) 主引用文献 Molecular basis of nucleotide-dependent substrate engagement and remodeling by an AAA+ activator. Nucleic Acids Res., 42, 2014
3FGA	Structural Basis of PP2A and Sgo interaction 分子名称: MANGANESE (II) ION, MICROCYSTIN-LR, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ... 著者 Xu, Z, Xu, W. 登録日 2008-12-05 公開日 2009-09-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure and function of the PP2A-shugoshin interaction Mol.Cell, 35, 2009

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