3FAT

X-ray structure of iGluR4 flip ligand-binding core (S1S2) in complex with (S)-AMPA at 1.90A resolution

Summary for 3FAT

Entry DOI	10.2210/pdb3fat/pdb
Related	1ftj 1ftm 2uxa 3FAS
Descriptor	Glutamate receptor 4, (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, SULFATE ION, ... (6 entities in total)
Functional Keywords	ionotropic glutamate receptors, iglur4, flip, ligand-binding core, agonist complex, membrane protein
Biological source	Rattus norvegicus (rat) More
Cellular location	Cell membrane; Multi-pass membrane protein: P19493
Total number of polymer chains	3
Total formula weight	89481.72
Authors	Kasper, C.,Frydenvang, K.,Naur, P.,Gajhede, M.,Kastrup, J.S. (deposition date: 2008-11-18, release date: 2008-12-09, Last modification date: 2023-11-01)
Primary citation	Kasper, C.,Frydenvang, K.,Naur, P.,Gajhede, M.,Pickering, D.S.,Kastrup, J.S. Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4 Febs Lett., 582:4089-4094, 2008 Cited by PubMed: 19022251 DOI: 10.1016/j.febslet.2008.11.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation