3FAT
X-ray structure of iGluR4 flip ligand-binding core (S1S2) in complex with (S)-AMPA at 1.90A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Glutamate receptor 4 | polymer | 260 | 29020.5 | 3 | UniProt (P19493) Pfam (PF10613) Pfam (PF00060) In PDB | Rattus norvegicus (rat) | ionotropic glutamate receptor 4, GluR-4, GluR4, GluR-D, Glutamate receptor ionotropic, AMPA 4, AMPA-selective glutamate receptor 4 |
| 2 | A, B, C | (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID | non-polymer | 186.2 | 3 | Chemie (AMQ) | |||
| 3 | A, B, C | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 4 | A, B, C | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 5 | C, A, B | ACETIC ACID | non-polymer | 60.1 | 6 | Chemie (ACY) | |||
| 6 | water | water | 18.0 | 630 | Chemie (HOH) |
Sequence modifications
A, B, C: 2 - 115 (UniProt: P19493)
A, B, C: 118 - 260 (UniProt: P19493)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 116 | - | linker |
| Thr 117 | - | linker |
| Ile 198 | Thr 734 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87061.6 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 2420.1 | |
| All* | Total formula weight | 89481.7 |
