1FTM

CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH AMPA AT 1.7 RESOLUTION

Summary for 1FTM

• Entry DOI: 10.2210/pdb1ftm/pdb
• Related: 1FTJ 1FTK 1FTL 1FTO 1FW0 1GR2
• Descriptor: GLUTAMATE RECEPTOR SUBUNIT 2, ZINC ION, (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, ... (4 entities in total)
• Functional Keywords: ampa receptor, glur2, s1s2, ligand-binding core, agonist, membrane protein
• Biological source: Rattus norvegicus (Norway rat); More
• Cellular location: Cell membrane; Multi-pass membrane protein: P19491
• Total number of polymer chains: 3
• Total formula weight: 88550.59

Authors

Gouaux, E.,Armstrong, N. (deposition date: 2000-09-12, release date: 2000-11-01, Last modification date: 2017-08-02)

• Primary citation: Armstrong, N.,Gouaux, E.; Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.; Neuron, 28:165-181, 2000; PubMed: 11086992; DOI: 10.1016/S0896-6273(00)00094-5

Experimental method

X-RAY DIFFRACTION (1.7 Å)