PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

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3CEY	Crystal structure of L3MBTL2 分子名称: Lethal(3)malignant brain tumor-like 2 protein 著者 Nady, N, Guo, Y, Pan, P, Allali-Hassani, A, Qi, C, Zhu, H, Dong, A, Mackenzie, F, Crombet, L, Loppnau, P, Kozieradzki, I, Vedadi, M, Edwards, A.M, Weigelt, J, Bountra, C, Arrowsmith, C.H, Bochkarev, A, Read, R, Min, J, Structural Genomics Consortium (SGC) 登録日 2008-02-29 公開日 2008-05-06 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2. Nucleic Acids Res., 37, 2009
4GKC	Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal at 1.33 分子名称: RETINAL, Retinol-binding protein 2 著者 Nossoni, Z, Geiger, J.H. 登録日 2012-08-10 公開日 2012-12-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Tuning the electronic absorption of protein-embedded all-trans-retinal. Science, 338, 2012
4FTI	Crystal Structure of the CHK1 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FTR	Crystal Structure of the CHK1 分子名称: 2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-8-yl]-N,N-dimethylacetamide, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
5L90	The crystal structure of substrate-free CYP109E1 from Bacillus megaterium at 2.55 Angstrom resolution 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2016-06-09 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium. Febs J., 283, 2016
3CTR	Crystal structure of the RRM-domain of the poly(A)-specific ribonuclease PARN bound to m7GTP 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Poly(A)-specific ribonuclease PARN 著者 Monecke, T, Schell, S, Dickmanns, A, Ficner, R. 登録日 2008-04-14 公開日 2008-07-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode. J.Mol.Biol., 382, 2008
2RCQ	Crystal structure of human apo Cellular Retinol Binding Protein II (CRBP-II) 分子名称: L(+)-TARTARIC ACID, Retinol-binding protein II, cellular, ... 著者 Monaco, H.L, Capaldi, S, Perduca, M. 登録日 2007-09-20 公開日 2007-10-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Crystal structure of human cellular retinol-binding protein II to 1.2 A resolution. Proteins, 70, 2007
3D3W	Structure of L-Xylulose Reductase with bound coenzyme, phosphate and hydroxide. 分子名称: L-xylulose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHOSPHATE ION 著者 Zhao, H.-T, El-Kabbani, O. 登録日 2008-05-12 公開日 2009-04-21 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structure/function analysis of a critical disulfide bond in the active site of L-xylulose reductase. Cell.Mol.Life Sci., 66, 2009
4G1Y	Structural basis for the accommodation of bis- and tris-aromatic derivatives in Vitamin D Nuclear Receptor 分子名称: (4E,6Z)-7-(3-{[3,4-bis(hydroxymethyl)benzyl]oxy}phenyl)-3-ethylnona-4,6-dien-3-ol, Nuclear receptor coactivator 1, Vitamin D3 receptor A 著者 Ciesielski, F, Sato, Y, Moras, D, Rochel, N. 登録日 2012-07-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural basis for the accommodation of bis- and tris-aromatic derivatives in vitamin d nuclear receptor. J.Med.Chem., 55, 2012
3D4U	Bovine thrombin-activatable fibrinolysis inhibitor (TAFIa) in complex with tick-derived carboxypeptidase inhibitor. 分子名称: ACETATE ION, Carboxypeptidase B2, Carboxypeptidase inhibitor, ... 著者 Sanglas, L, Valnickova, Z, Arolas, J.L, Pallares, I, Guevara, T, Sola, M, Kristensen, T, Enghild, J.J, Aviles, F.X, Gomis-Ruth, F.X. 登録日 2008-05-15 公開日 2008-08-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of activated thrombin-activatable fibrinolysis inhibitor, a molecular link between coagulation and fibrinolysis. Mol.Cell, 31, 2008
3CWD	Molecular recognition of nitro-fatty acids by PPAR gamma 分子名称: (9E,12Z)-10-nitrooctadeca-9,12-dienoic acid, (9Z,12E)-12-nitrooctadeca-9,12-dienoic acid, Peroxisome proliferator-activated receptor gamma, ... 著者 Martynowski, D, Li, Y. 登録日 2008-04-21 公開日 2008-07-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular recognition of nitrated fatty acids by PPAR gamma. Nat.Struct.Mol.Biol., 15, 2008
2RLQ	NMR structure of CCP modules 2-3 of complement factor H 分子名称: Complement factor H 著者 Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D. 登録日 2007-07-29 公開日 2008-02-19 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations. J.Biol.Chem., 283, 2008
3D6F	Crystal structure of human caspase-1 with a naturally-occurring Arg240->Gln substitution in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK) 分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide 著者 Rosen-Wolff, A, Roesler, J, Romanowski, M.J. 登録日 2008-05-19 公開日 2010-03-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mutated, structurally altered caspase-1 with decreased enzymatic and increased RIP2-meditated inflammatory activity leads to a new type of periodic fever (ICE fever). To be Published
4FXL	Crystal structure of the D76N Beta-2 Microglobulin mutant 分子名称: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... 著者 Ricagno, S, Bellotti, V, Pepys, M.B, Stoppini, M, Bolognesi, M. 登録日 2012-07-03 公開日 2012-08-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Hereditary systemic amyloidosis due to Asp76Asn variant beta-2-microglobulin. N.Engl.J.Med., 366, 2012
4GD7	Wild-Type Human Thymidylate Synthase with bound Purpurogallin 分子名称: 1,2-ETHANEDIOL, 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one, SULFATE ION, ... 著者 Celeste, L.R, Lebioda, L. 登録日 2012-07-31 公開日 2013-07-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Oxidation of Cysteine 195 of Huyman Thymidylate Synthase by Purpurogallin To be published, 2012
3D2W	Crystal structure of mouse TDP-43 RRM2 domain in complex with DNA 分子名称: DNA (5'-D(*DGP*DTP*DTP*DGP*DAP*DGP*DCP*DGP*DTP*DT)-3'), PHOSPHATE ION, TAR DNA-binding protein 43 著者 Kuo, P.H, Yuan, H.S. 登録日 2008-05-09 公開日 2009-04-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural insights into TDP-43 in nucleic-acid binding and domain interactions Nucleic Acids Res., 37, 2009
3D48	Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptor 分子名称: CARBONATE ION, Prolactin, Prolactin receptor 著者 Svensson, L.A, Breinholt, J. 登録日 2008-05-14 公開日 2008-06-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptor J.Biol.Chem., 283, 2008
3D57	TR Variant D355R 分子名称: SULFATE ION, Thyroid hormone receptor beta, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID 著者 Jouravel, N. 登録日 2008-05-15 公開日 2008-10-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular basis for dimer formation of TRbeta variant D355R. Proteins, 75, 2008
3D5Q	Crystal Structure of 11b-HSD1 in Complex with Triazole Inhibitor 分子名称: 3-[1-(4-fluorophenyl)cyclopropyl]-4-(1-methylethyl)-5-[4-(trifluoromethoxy)phenyl]-4H-1,2,4-triazole, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Wang, Z, Liu, J, Sudom, A, Walker, N.P.C. 登録日 2008-05-16 公開日 2008-10-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. Bioorg.Med.Chem., 16, 2008
4G7W	Crystal structure of the N-terminal domain of the minor coat protein pIII from CTXphi 分子名称: Putative uncharacterized protein 著者 Kolappan, S, Ford, C.G, Craig, L. 登録日 2012-07-20 公開日 2012-08-29 最終更新日 2012-11-07 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structures of a CTX{varphi} pIII Domain Unbound and in Complex with a Vibrio cholerae TolA Domain Reveal Novel Interaction Interfaces. J.Biol.Chem., 287, 2012
4FSR	Crystal Structure of the CHK1 分子名称: 6,7-dimethoxy-3-[4-(1H-tetrazol-5-yl)phenyl]-1,4-dihydroindeno[1,2-c]pyrazole, SULFATE ION, Serine/threonine-protein kinase Chk1 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4G9C	Human B-Raf Kinase Domain bound to a Type II Pyrazolopyridine Inhibitor 分子名称: 3-{[3-(2-cyanopropan-2-yl)benzoyl]amino}-2,6-difluoro-N-(3-methoxy-2H-pyrazolo[3,4-b]pyridin-5-yl)benzamide, Serine/threonine-protein kinase B-raf 著者 Voegtli, W.C, Sturgis, H.L. 登録日 2012-07-23 公開日 2012-11-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Pyrazolopyridine inhibitors of B-Raf(V600E). Part 4: Rational design and kinase selectivity profile of cell potent type II inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
2RFE	Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide 分子名称: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor 著者 Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J. 登録日 2007-09-28 公開日 2007-12-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature, 450, 2007
2RHP	The Thrombospondin-1 Polymorphism Asn700Ser Associated with Cornoary Artery Disease Causes Local and Long-Ranging Changes in Protein Structure 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Carlson, C.B, Keck, J.L, Mosher, D.F. 登録日 2007-10-09 公開日 2008-05-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Influences of the N700S Thrombospondin-1 Polymorphism on Protein Structure and Stability. J.Biol.Chem., 283, 2008
3CQG	Nucleoporin Nup107/Nup133 interaction complex, delta finger mutant 分子名称: Nuclear pore complex protein Nup107, Nuclear pore complex protein Nup133 著者 Jeudy, S, Boehmer, T, Berke, I, Schwartz, T.U. 登録日 2008-04-02 公開日 2008-07-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural and functional studies of Nup107/Nup133 interaction and its implications for the architecture of the nuclear pore complex. Mol.Cell, 30, 2008

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