8Y3R
 
 | | ASFV p72 in complex with Fab H3 | | 分子名称: | B646L, Heavy chain of H3, Light chain of H3 | | 著者 | Wang, X, Fu, W, Yu, Q. | | 登録日 | 2024-01-29 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | p72 antigenic mapping reveals a potential supersite of vulnerability for African swine fever virus.
Cell Discov, 10, 2024
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1SVX
 | | Crystal structure of a designed selected Ankyrin Repeat protein in complex with the Maltose Binding Protein | | 分子名称: | Ankyrin Repeat Protein off7, Maltose-binding periplasmic protein | | 著者 | Binz, H.K, Amstutz, P, Kohl, A, Stumpp, M.T, Briand, C, Forrer, P, Gruetter, M.G, Plueckthun, A. | | 登録日 | 2004-03-30 | | 公開日 | 2004-05-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | High-affinity binders selected from designed ankyrin repeat protein libraries
NAT.BIOTECHNOL., 22, 2004
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4WY7
 | | Crystal structure of recombinant 4E10 expressed in Escherichia coli with epitope bound | | 分子名称: | Envelope glycoprotein gp160, Fab 4E10 Heavy chain, Fab 4E10Light chain, ... | | 著者 | Rujas, E, Morante, K, Tsumoto, K, Nieva, J.L, Caaveiro, J.M.M. | | 登録日 | 2014-11-16 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region.
J.Biol.Chem., 290, 2015
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3QB4
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1T8C
 | | Structure of the C-type lectin domain of CD23 | | 分子名称: | Low affinity immunoglobulin epsilon Fc receptor | | 著者 | Hibbert, R.G, Teriete, P, Grundy, G.J, Sutton, B.J, Gould, H.J, McDonnell, J.M. | | 登録日 | 2004-05-12 | | 公開日 | 2005-07-26 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of human CD23 and its interactions with IgE and CD21
J.Exp.Med., 202, 2005
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1IJN
 | | Crystal structure of the transthyretin mutant TTR C10A/Y114C | | 分子名称: | BETA-MERCAPTOETHANOL, TRANSTHYRETIN | | 著者 | Eneqvist, T, Karlsson, A, Olofsson, A, Sauer-Eriksson, A.E. | | 登録日 | 2001-04-27 | | 公開日 | 2003-06-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Cys114-linked dimers of transthyretin are compatible with amyloid formation
Biochemistry, 44, 2005
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1III
 | | CRYSTAL STRUCTURE OF THE TRANSTHYRETIN MUTANT TTR Y114C-DATA COLLECTED AT ROOM TEMPERATURE | | 分子名称: | BETA-MERCAPTOETHANOL, TRANSTHYRETIN | | 著者 | Eneqvist, T, Olofsson, A, Ando, Y, Lundgren, E, Sauer-Eriksson, A.E. | | 登録日 | 2001-04-23 | | 公開日 | 2002-11-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Disulfide-Bond Formation in the Transthyretin Mutant Y114C Prevents Amyloid Fibril Formation in Vivo and in Vitro
Biochemistry, 41, 2002
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5EGC
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3QT4
 | | Structure of digestive procathepsin L 3 of Tenebrio molitor larval midgut | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, Cathepsin-L-like midgut cysteine proteinase, PHOSPHATE ION, ... | | 著者 | Beton, D, Guzzo, C.R, Terra, W.R, Farah, C.S. | | 登録日 | 2011-02-22 | | 公開日 | 2012-02-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | The 3D structure and function of digestive cathepsin L-like proteinases of Tenebrio molitor larval midgut.
Insect Biochem.Mol.Biol., 42, 2012
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1IJS
 | | CPV (STRAIN D) mutant A300D, complex (VIRAL COAT/DNA), VP2, PH=7.5, T=4 DEGREES C | | 分子名称: | DNA (5'-D(*AP*C)-3'), DNA (5'-D(*CP*CP*AP*CP*CP*CP*CP*AP*A)-3'), PROTEIN (PARVOVIRUS COAT PROTEIN) | | 著者 | Llamas-Saiz, A.L, Agbandje-McKenna, M, Parker, J.S.L, Wahid, A.T.M, Parrish, C.R, Rossmann, M.G. | | 登録日 | 1996-09-12 | | 公開日 | 1996-12-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural analysis of a mutation in canine parvovirus which controls antigenicity and host range.
Virology, 225, 1996
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1IIK
 | | CRYSTAL STRUCTURE OF THE TRANSTHYRETIN MUTANT TTR Y114C-DATA COLLECTED AT CRYO TEMPERATURE | | 分子名称: | BETA-MERCAPTOETHANOL, TRANSTHYRETIN | | 著者 | Eneqvist, T, Olofsson, A, Ando, Y, Lundgren, E, Sauer-Eriksson, A.E. | | 登録日 | 2001-04-23 | | 公開日 | 2002-11-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Disulfide-Bond Formation in the Transthyretin Mutant Y114C Prevents Amyloid Fibril Formation in Vivo and in Vitro
Biochemistry, 41, 2002
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3H4Z
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3LRH
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3LRG
 | | Structure of anti-huntingtin VL domain | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IMIDAZOLE, anti-huntingtin VL domain | | 著者 | Schiefner, A, Chatwell, L, Skerra, A. | | 登録日 | 2010-02-11 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | A Disulfide-Free Single-Domain V(L) Intrabody with Blocking Activity towards Huntingtin Reveals a Novel Mode of Epitope Recognition.
J.Mol.Biol., 414, 2011
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1ALY
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4XAV
 | | Crystal structure of olfactomedin domain from gliomedin | | 分子名称: | GLYCEROL, Gliomedin, PHOSPHATE ION, ... | | 著者 | Hill, S.E, Nguyen, E, Lieberman, R.L. | | 登録日 | 2014-12-15 | | 公開日 | 2015-07-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.052 Å) | | 主引用文献 | Molecular Details of Olfactomedin Domains Provide Pathway to Structure-Function Studies.
Plos One, 10, 2015
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6EHG
 | | complement component C3b in complex with a nanobody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Jensen, R.K, Andersen, K.R, Gadeberg, T.A.F, Laursen, N.S, Andersen, G.R. | | 登録日 | 2017-09-13 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.
J. Biol. Chem., 293, 2018
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5ETU
 | | Cetuximab Fab in complex with L5E meditope variant | | 分子名称: | Cetuximab Fab heavy chain, Cetuximab Fab light chain, L5E meditope variant, ... | | 著者 | Bzymek, K.P, Williams, J.C. | | 登録日 | 2015-11-18 | | 公開日 | 2016-10-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
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4XAT
 | | Crystal structure of the olfactomedin domain from noelin/pancortin/olfactomedin-1 | | 分子名称: | CALCIUM ION, GLYCEROL, Noelin, ... | | 著者 | Hill, S.E, Nguyen, E, Lieberman, R.L. | | 登録日 | 2014-12-15 | | 公開日 | 2015-07-15 | | 最終更新日 | 2022-03-30 | | 実験手法 | X-RAY DIFFRACTION (2.113 Å) | | 主引用文献 | Molecular Details of Olfactomedin Domains Provide Pathway to Structure-Function Studies.
Plos One, 10, 2015
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3S1K
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6F6R
 | | Crystal structure of human Caspase-1 with N-{3-[1-((S)-2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-ethyl]-1-methyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl}-4-(quinoxalin-2-ylamino)-benzamide | | 分子名称: | (3~{S})-3-[[(2~{R})-2-[3-methyl-2,6-bis(oxidanylidene)-5-[[4-(quinoxalin-2-ylamino)phenyl]carbonylamino]pyrimidin-1-yl]propanoyl]amino]-4-oxidanyl-butanoic acid, Caspase-1, SULFATE ION | | 著者 | Fournier, J.F, Clary, L, Chambon, S, Dumais, L, Harris, C.S, Millois-Barbuis, C, Pierre, R, Talano, S, Thoreau, E, Aubert, J, Aurelly, M, Bouix-Peter, C, Brethon, A, Chantalat, L, Christin, O, Comino, C, El-Bazbouz, G, Ghilini, A.L, Isabet, T, Lardy, C, Luzy, A.P, Mathieu, C, Mebrouk, K, Orfila, D, Pascau, J, Reverse, K, Roche, D, Rodeschini, V, Hennequin, L.F. | | 登録日 | 2017-12-06 | | 公開日 | 2018-05-02 | | 最終更新日 | 2018-05-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Rational Drug Design of Topically Administered Caspase 1 Inhibitors for the Treatment of Inflammatory Acne.
J. Med. Chem., 61, 2018
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1R21
 | | Solution Structure of human Ki67 FHA Domain | | 分子名称: | Antigen Ki-67 | | 著者 | Byeon, I.J, Li, H, Tsai, M.D. | | 登録日 | 2003-09-25 | | 公開日 | 2003-12-30 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of Human Ki67 FHA Domain and its Binding to a Phosphoprotein Fragment from hNIFK Reveal Unique Recognition Sites and New Views to the Structural Basis of FHA Domain Functions
J.Mol.Biol., 335, 2004
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3RY6
 | | Complex of fcgammariia (CD32) and the FC of human IGG1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ig gamma-1 chain C region, ... | | 著者 | Ramsland, P.A, Farrugia, W, Scott, A.M, Hogarth, P.M. | | 登録日 | 2011-05-11 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structural Basis for Fc{gamma}RIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes.
J.Immunol., 187, 2011
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3CHN
 | | Solution structure of human secretory IgA1 | | 分子名称: | Ig alpha-1 chain C region, Immunoglobulin kappa light chain, Secretory component | | 著者 | Bonner, A, Almogren, A, Furtado, P.B, Kerr, M.A, Perkins, S.J. | | 登録日 | 2008-03-10 | | 公開日 | 2008-12-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | Location of secretory component on the Fc edge of dimeric IgA1 reveals insight into the role of secretory IgA1 in mucosal immunity.
Mucosal Immunol, 2, 2009
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7WPO
 | | Structure of NeoCOV RBD binding to Bat37 ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Cao, L, Wang, X, Tortorici, M.A, Veesler, D. | | 登録日 | 2022-01-24 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Close relatives of MERS-CoV in bats use ACE2 as their functional receptors.
Nature, 612, 2022
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