Summary for 6EHG
| Descriptor | Complement C3, hC3Nb1, N-ACETYL-D-GLUCOSAMINE, ... (5 entities in total) |
|---|---|
| Functional Keywords | protein complex, inhibitor, complement, complement system, single domain antibody, nanobody, immune system |
| Biological source | Lama glama (llama) More |
| Total number of polymer chains | 3 |
| Total molecular weight | 190572.04 |
| Authors | Jensen, R.K.,Andersen, K.R.,Gadeberg, T.A.F.,Laursen, N.S.,Andersen, G.R. (deposition date: 2017-09-13, release date: 2018-02-14, Last modification date: 2019-10-16) |
| Primary citation | Jensen, R.K.,Pihl, R.,Gadeberg, T.A.F.,Jensen, J.K.,Andersen, K.R.,Thiel, S.,Laursen, N.S.,Andersen, G.R. A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement. J. Biol. Chem., 293:6269-6281, 2018 PubMed: 29497000 (PDB entries with the same primary citation) DOI: 10.1074/jbc.RA117.001179  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2.65 Å) |
