6EHG
complement component C3b in complex with a nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Complement C3 | polymer | 643 | 71265.2 | 1 | UniProt (P01024) Pfam (PF17790) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) In PDB | Homo sapiens (Human) | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
| 2 | B | Complement C3 | polymer | 915 | 104117.2 | 1 | UniProt (P01024) Pfam (PF07677) Pfam (PF01759) Pfam (PF00207) Pfam (PF21406) Pfam (PF07678) Pfam (PF21308) In PDB | Homo sapiens (Human) | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
| 3 | C | hC3Nb1 | polymer | 130 | 14345.9 | 1 | Lama glama (llama) | ||
| 4 | D | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A: 23 - 665 (UniProt: P01024)
B: 749 - 1663 (UniProt: P01024)
| PDB | External Database | Details |
|---|---|---|
| Glu 395 | Asp 395 | conflict |
| Ile 431 | Leu 431 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Glu 1013 | Gln 1013 | conflict |
| Asn 1380 | Ala 1380 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 189728.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 190536.0 |
