PDB: 105044 件ウェブページステータス検索Chemie searchBIRD

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1LJY	Crystal Structure of a Novel Regulatory 40 kDa Mammary Gland Protein (MGP-40) secreted during Involution 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MGP-40 著者 Mohanty, A.K, Singh, G, Paramasivam, M, Saravanan, K, Jabeen, T, Sharma, S, Yadav, S, Kaur, P, Kumar, P, Srinivasan, A, Singh, T.P. 登録日 2002-04-23 公開日 2003-03-18 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of a Novel Regulatory 40 kDa Mammary Gland Protein (MGP-40) secreted during Involution J.Biol.Chem., 278, 2003
6W45	Crystal structure of HAO1 in complex with biaryl acid inhibitor - compound 3 分子名称: 2-chloranyl-4-[2-[[(6-chloranyl-1~{H}-indol-2-yl)carbonyl-methyl-amino]methyl]-5-fluoranyl-phenyl]benzoic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 1 著者 Ferguson, A.D. 登録日 2020-03-10 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening. J.Med.Chem., 64, 2021
6DFE	The structure of a ternary complex of E. coli WaaC 分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-acetamido-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, ADP-heptose--LPS heptosyltransferase, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R)-1-{(2S,3S,4R,5S,6R)-6-[(1S)-1,2-dihydroxyethyl]-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl}propan-2-yl hydrogen (R)-phosphate (non-preferred name) 著者 Worrall, L.J, Blaukopf, M, Withers, S.G, Strynadka, N.C.J. 登録日 2018-05-14 公開日 2018-09-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Insights into Heptosyltransferase I Catalysis and Inhibition through the Structure of Its Ternary Complex. Structure, 26, 2018
4V88	The structure of the eukaryotic ribosome at 3.0 A resolution. 分子名称: 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ... 著者 Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M. 登録日 2011-10-11 公開日 2014-07-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of the eukaryotic ribosome at 3.0 angstrom resolution. Science, 334, 2011
4UYJ	Crystal structure of a Signal Recognition Particle Alu domain in the elongation arrest conformation 分子名称: SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN, SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN, SRP RNA 著者 Bousset, L, Mary, C, Brooks, M.A, Scherrer, A, Strub, K, Cusack, S. 登録日 2014-09-01 公開日 2014-11-05 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Crystal Structure of a Signal Recognition Particle Alu Domain in the Elongation Arrest Conformation. RNA, 20, 2014
3FX4	Porcine aldehyde reductase in ternary complex with inhibitor 分子名称: Alcohol dehydrogenase [NADP+], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... 著者 Carbone, V, El-Kabbani, O. 登録日 2009-01-20 公開日 2009-12-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structure of aldehyde reductase in ternary complex with a 5-arylidene-2,4-thiazolidinedione aldose reductase inhibitor. Eur.J.Med.Chem., 45, 2010
7AZY	Context-specific inhibition of eukaryotic translation by macrolide antibiotics 分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Koller, T.O, Wilson, D.N. 登録日 2020-11-17 公開日 2021-05-19 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.877 Å) 主引用文献 Context-specific action of macrolide antibiotics on the eukaryotic ribosome. Nat Commun, 12, 2021
6YLV	Translation initiation factor 4E in complex with 4-Cl-Bn7GpppG mRNA 5' cap analog 分子名称: 4-Cl-Bn7GpppG mRNA 5' cap analog, Eukaryotic translation initiation factor 4E, GLYCEROL 著者 Kubacka, D, Wojcik, R, Baranowski, M.R, Kowalska, J, Jemielity, J. 登録日 2020-04-07 公開日 2020-06-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.66005659 Å) 主引用文献 Novel N7-Arylmethyl Substituted Dinucleotide mRNA 5' cap Analogs: Synthesis and Evaluation as Modulators of Translation. Pharmaceutics, 13, 2021
4V6U	Promiscuous behavior of proteins in archaeal ribosomes revealed by cryo-EM: implications for evolution of eukaryotic ribosomes 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10P, ... 著者 Armache, J.-P, Anger, A.M, Marquez, V, Frankenberg, S, Froehlich, T, Villa, E, Berninghausen, O, Thomm, M, Arnold, G.J, Beckmann, R, Wilson, D.N. 登録日 2012-08-09 公開日 2014-07-09 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Promiscuous behaviour of archaeal ribosomal proteins: Implications for eukaryotic ribosome evolution. Nucleic Acids Res., 41, 2013
1KAL	ELUCIDATION OF THE PRIMARY AND THREE-DIMENSIONAL STRUCTURE OF THE UTEROTONIC POLYPEPTIDE KALATA B1 分子名称: KALATA B1 著者 Craik, D.J, Norman, D.G. 登録日 1995-01-13 公開日 1995-03-31 最終更新日 2024-10-23 実験手法 SOLUTION NMR 主引用文献 Elucidation of the primary and three-dimensional structure of the uterotonic polypeptide kalata B1. Biochemistry, 34, 1995
3JYC	Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 Angstrom resolution 分子名称: Inward-rectifier K+ channel Kir2.2, POTASSIUM ION 著者 Tao, X. 登録日 2009-09-21 公開日 2010-01-12 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 A resolution. Science, 326, 2009
5K4C	Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 2 分子名称: Eukaryotic translation initiation factor 3 subunit D, GLYCEROL 著者 Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. 登録日 2016-05-20 公開日 2016-07-27 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation. Nature, 536, 2016
3KTQ	CRYSTAL STRUCTURE OF AN ACTIVE TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*DOC)-3'), ... 著者 Li, Y, Waksman, G. 登録日 1998-07-28 公開日 1999-01-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation. EMBO J., 17, 1998
4V0U	The crystal structure of ternary PP1G-PPP1R15B and G-actin complex 分子名称: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Chen, R, Yan, Y, Casado, A.C, Ron, D, Read, R.J. 登録日 2014-09-18 公開日 2015-03-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (7.88 Å) 主引用文献 G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases. Elife, 4, 2015
2X66	The binary complex of PrnB (the second enzyme in pyrrolnitrin biosynthesis pathway) and cyanide 分子名称: CYANIDE ION, PRNB, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Zhu, X, van pee, K.-H, Naismith, J.H. 登録日 2010-02-15 公開日 2010-03-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 The Ternary Complex of Prnb (the Second Enzyme in Pyrrolnitrin Biosynthesis Pathway), Tryptophan and Cyanide Yields New Mechanistic Insights Into the Indolamine Dioxygenase Superfamily. J.Biol.Chem., 285, 2010
2CSC	Structure of ternary complexes of CITRATE SYNTHASE WITH D-AND L-MALATE: mechanistic implications 分子名称: CARBOXYMETHYL COENZYME *A, CITRATE SYNTHASE, D-MALATE 著者 Karpusas, M, Holland, D, Remington, S.J. 登録日 1990-05-07 公開日 1991-04-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 1.9-A structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications. Biochemistry, 30, 1991
4UW1	X-ray crystal structure of human TNKS in complex with a small molecule inhibitor 分子名称: 1,2-ETHANEDIOL, 3-{4-[(dimethylamino)methyl]phenyl}-5-methoxyisoquinolin-1(2H)-one, GLYCEROL, ... 著者 Oliver, A.W, Rajasekaran, M.B, Pearl, L.H. 登録日 2014-08-08 公開日 2015-07-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.37 Å) 主引用文献 Design and Discovery of 3-Aryl-5-Substituted-Isoquinolin-1-Ones as Potent and Selective Tankyrase Inhibitors Medchemcommm, 6, 2015
3CV7	Crystal structure of porcine aldehyde reductase ternary complex 分子名称: 3,5-dichloro-2-hydroxybenzoic acid, Alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Carbone, V, El-Kabbani, O. 登録日 2008-04-18 公開日 2008-10-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.412 Å) 主引用文献 Structure of aldehyde reductase in ternary complex with coenzyme and the potent 20alpha-hydroxysteroid dehydrogenase inhibitor 3,5-dichlorosalicylic acid: Implications for inhibitor binding and selectivity Arch.Biochem.Biophys., 479, 2008
5DGE	Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. 登録日 2015-08-27 公開日 2017-01-25 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
6F5Z	Complex between the Haloferax volcanii Trm112 methyltransferase activator and the Hvo_0019 putative methyltransferase 分子名称: 24-sterol C-methyltransferase, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Graille, M, van Tran, N. 登録日 2017-12-04 公開日 2018-07-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes. Nucleic Acids Res., 46, 2018
4V3P	The molecular structure of the left-handed supra-molecular helix of eukaryotic polyribosomes 分子名称: 18S ribosomal RNA, 26S ribosomal RNA, 40S WHEAT GERM RIBOSOME protein 4, ... 著者 Myasnikov, A.G, Afonina, Z.A, Menetret, J.F, Shirokov, V.A, Spirin, A.S, Klaholz, B.P. 登録日 2014-10-20 公開日 2015-04-22 最終更新日 2025-04-09 実験手法 ELECTRON MICROSCOPY (34 Å) 主引用文献 The molecular structure of the left-handed supra-molecular helix of eukaryotic polyribosomes. Nat Commun, 5, 2014
3DCI	The Structure of a putative arylesterase from Agrobacterium tumefaciens str. C58 分子名称: ACETIC ACID, Arylesterase, CHLORIDE ION, ... 著者 Cuff, M.E, Xu, X, Zheng, H, Binkowski, T.A, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2008-06-03 公開日 2008-09-30 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Structure of a putative arylesterase from Agrobacterium tumefaciens str. C58 TO BE PUBLISHED
2IHQ	Crystal Structure of the Rat Androgen Receptor Ligand Binding Domian Complex with an N-Aryl-Hydroxybicyclohydantoin 分子名称: 4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE, Androgen receptor 著者 Sack, J.S. 登録日 2006-09-27 公開日 2006-12-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of potent, orally-active, and muscle-selective androgen receptor modulators based on an N-aryl-hydroxybicyclohydantoin scaffold. J.Med.Chem., 49, 2006
5Y50	Crystal structure of eukaryotic MATE transporter AtDTX14 分子名称: Protein DETOXIFICATION 14 著者 Miyauchi, H, Kusakizako, T, Nishizawa, T, Ishitani, R, Nureki, O. 登録日 2017-08-06 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for xenobiotic extrusion by eukaryotic MATE transporter Nat Commun, 8, 2017
5ZD0	Solution structure of human ubiquitin with three alanine mutations in living eukaryotic cells by in-cell NMR spectroscopy 分子名称: ubiquitin 著者 Tanaka, T, Ikeya, T, Kamoshida, H, Mishima, M, Shirakawa, M, Guentert, P, Ito, Y. 登録日 2018-02-22 公開日 2019-08-21 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 High-Resolution Protein 3D Structure Determination in Living Eukaryotic Cells. Angew.Chem.Int.Ed.Engl., 58, 2019

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