6YLV

Translation initiation factor 4E in complex with 4-Cl-Bn7GpppG mRNA 5' cap analog

Summary for 6YLV

Entry DOI	10.2210/pdb6ylv/pdb
Descriptor	Eukaryotic translation initiation factor 4E, 4-Cl-Bn7GpppG mRNA 5' cap analog, GLYCEROL, ... (4 entities in total)
Functional Keywords	cap analog, translation initiation factor, 4-cl-bn7gpppg, protein-ligand complex, eif4e, rna binding protein, translation
Biological source	Mus musculus (House mouse)
Total number of polymer chains	4
Total formula weight	92945.35
Authors	Kubacka, D.,Wojcik, R.,Baranowski, M.R.,Kowalska, J.,Jemielity, J. (deposition date: 2020-04-07, release date: 2020-06-10, Last modification date: 2024-01-24)
Primary citation	Wojcik, R.,Baranowski, M.R.,Markiewicz, L.,Kubacka, D.,Bednarczyk, M.,Baran, N.,Wojtczak, A.,Sikorski, P.J.,Zuberek, J.,Kowalska, J.,Jemielity, J. Novel N7-Arylmethyl Substituted Dinucleotide mRNA 5' cap Analogs: Synthesis and Evaluation as Modulators of Translation. Pharmaceutics, 13:-, 2021 Cited by PubMed: 34834356 DOI: 10.3390/pharmaceutics13111941 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.66005667871 Å)

Structure validation