PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

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6M8B	Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with kaempferol 分子名称: 3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE, Inositol polyphosphate multikinase,Inositol polyphosphate multikinase 著者 Wang, H, Shears, S.B. 登録日 2018-08-21 公開日 2019-01-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis. J. Med. Chem., 62, 2019
3F83	Structure of fusion complex of the minor pilin CfaE and major pilin CfaB of CFA/I pili from ETEC E. coli 分子名称: Fusion of the minor pilin CfaE and major pilin CfaB, SODIUM ION, SULFATE ION 著者 Xia, D, Li, Y.F. 登録日 2008-11-11 公開日 2009-08-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of CFA/I fimbriae from enterotoxigenic Escherichia coli. Proc.Natl.Acad.Sci.USA, 106, 2009
3FJU	Ascaris suum carboxypeptidase inhibitor in complex with human carboxypeptidase A1 分子名称: ACETATE ION, CACODYLATE ION, Carboxypeptidase A inhibitor, ... 著者 Sanglas, L, Aviles, F.X, Huber, R, Gomis-Ruth, F.X, Arolas, J.L. 登録日 2008-12-15 公開日 2008-12-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Mammalian metallopeptidase inhibition at the defense barrier of Ascaris parasite Proc.Natl.Acad.Sci.USA, 106, 2009
3F64	F17a-G lectin domain with bound GlcNAc(beta1-O)paranitrophenyl ligand 分子名称: 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, F17a-G 著者 Buts, L, De Boer, A, Olsson, J.D.M, Jonckheere, W, De Kerpel, M, De Genst, E, Guerardel, Y, Willaert, R, Wyns, L, Wuhrer, M, Oscarson, S, De Greve, H, Bouckaert, J. 登録日 2008-11-05 公開日 2009-11-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Sampling of Glycan Interaction Profiles Reveals Mucosal Receptors for Fimbrial Adhesins of Enterotoxigenic Escherichia coli. Biology (Basel), 2, 2013
4NG0	Lar_0958 a cell surface adhesin from lactobacillus reuteri 分子名称: LAR_0958 cell surface adhesin 著者 Etzold, S, Mackenzie, D.A, Juge, N, Hemmings, A.M. 登録日 2013-11-01 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.501 Å) 主引用文献 Structural and molecular insights into novel surface-exposed mucus adhesins from Lactobacillus reuteri human strains. Mol.Microbiol., 92, 2014
3FJQ	Crystal structure of cAMP-dependent protein kinase catalytic subunit alpha in complex with peptide inhibitor PKI alpha (6-25) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Kim, C. 登録日 2008-12-15 公開日 2009-08-04 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Comparative surface geometry of the protein kinase family. Protein Sci., 18, 2009
3FEY	Crystal structure of the CBC-importin alpha complex. 分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2 著者 Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A. 登録日 2008-12-01 公開日 2009-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The molecular basis for the regulation of the cap-binding complex by the importins. Nat.Struct.Mol.Biol., 16, 2009
3F85	Structure of fusion complex of homo trimeric major pilin subunits CfaB of CFA/I fimbirae from ETEC E. coli 分子名称: MAGNESIUM ION, homo trimeric fusion of CFA/I fimbrial subunits B 著者 Xia, D, Li, Y.F. 登録日 2008-11-11 公開日 2009-08-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of CFA/I fimbriae from enterotoxigenic Escherichia coli. Proc.Natl.Acad.Sci.USA, 106, 2009
5FU6	NOT module of the human CCR4-NOT complex (Crystallization mutant) 分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 著者 Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E. 登録日 2016-01-21 公開日 2016-03-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos Embo J., 35, 2016
3FGA	Structural Basis of PP2A and Sgo interaction 分子名称: MANGANESE (II) ION, MICROCYSTIN-LR, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ... 著者 Xu, Z, Xu, W. 登録日 2008-12-05 公開日 2009-09-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure and function of the PP2A-shugoshin interaction Mol.Cell, 35, 2009
3FMD	Crystal Structure of Human Haspin with an Isoquinoline ligand 分子名称: 1,2-ETHANEDIOL, N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, NICKEL (II) ION, ... 著者 Filippakopoulos, P, Eswaran, J, Keates, T, Burgess-Brown, N, Fedorov, O, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2008-12-21 公開日 2008-12-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Human Haspin with an Isoquinoline ligand To be Published
3FWV	Crystal Structure of a Redesigned TPR Protein, T-MOD(VMY), in Complex with MEEVF Peptide 分子名称: Heat shock protein HSP 90-beta, Hsc70/Hsp90-organizing protein, NICKEL (II) ION 著者 Jackrel, M.E, Valverde, R, Regan, L. 登録日 2009-01-19 公開日 2009-04-21 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Redesign of a protein-peptide interaction: characterization and applications Protein Sci., 18, 2009
3G0W	Crystal structure of the rat androgen receptor ligand binding domain complex with an n-aryl-oxazolidin 2-imine inhibitor 分子名称: 2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-met hylbenzonitrile, Androgen receptor 著者 Sack, J.S. 登録日 2009-01-29 公開日 2009-04-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 N-aryl-oxazolidin-2-imine muscle selective androgen receptor modulators enhance potency through pharmacophore reorientation. J.Med.Chem., 52, 2009
3G0L	Crystal Structure of Human Bromodomain Adjacent to Zinc finger domain 2B (BAZ2B) 分子名称: 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B 著者 Filippakopoulos, P, Keates, T, Salah, E, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2009-01-28 公開日 2009-02-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Crystal Structure of Human Bromodomain Adjacent to Zinc finger domain 2B (BAZ2B) To be Published
3G5U	Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding 分子名称: MERCURY (II) ION, Multidrug resistance protein 1a 著者 Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G. 登録日 2009-02-05 公開日 2009-03-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science, 323, 2009
3DYS	human phosphodiestrase-5'GMP complex (EP), produced by soaking with 20mM cGMP+20 mM MnCl2+20 mM MgCl2 for 2 hours, and flash-cooled to liquid nitrogen temperature when substrate was still abudant. 分子名称: 3-ISOBUTYL-1-METHYLXANTHINE, FORMIC ACID, GUANOSINE-5'-MONOPHOSPHATE, ... 著者 Liu, S, Mansour, M.N, Dillman, K, Perez, J, Danley, D, Menniti, F. 登録日 2008-07-28 公開日 2008-09-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for the catalytic mechanism of human phosphodiesterase 9. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DWA	Crystal structure of the B-subunit of the AB5 toxin from E. coli 分子名称: PENTAETHYLENE GLYCOL, Subtilase cytotoxin, subunit B 著者 Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. 登録日 2008-07-22 公開日 2008-11-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.084 Å) 主引用文献 Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
3DWP	Crystal structure of the B-subunit of the AB5 toxin from E. Coli with Neu5Gc 分子名称: N-glycolyl-alpha-neuraminic acid, PENTAETHYLENE GLYCOL, Subtilase cytotoxin, ... 著者 Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. 登録日 2008-07-22 公開日 2008-11-04 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
3DYQ	human phosphodiestrase 9 (inhibited by omitting divalent cation) in complex with cGMP 分子名称: 3-ISOBUTYL-1-METHYLXANTHINE, CYCLIC GUANOSINE MONOPHOSPHATE, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ... 著者 Liu, S, Mansour, M.N, Dillman, K, Perez, J, Danley, D, Menniti, F. 登録日 2008-07-28 公開日 2008-09-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for the catalytic mechanism of human phosphodiesterase 9. Proc.Natl.Acad.Sci.Usa, 105, 2008
3G61	Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding 分子名称: (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a 著者 Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G. 登録日 2009-02-05 公開日 2009-03-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (4.35 Å) 主引用文献 Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science, 323, 2009
3GFW	Crystal Structure of Human Dual Specificity Protein Kinase (TTK) in complex with a pyrolo-pyridin ligand 分子名称: 1-(4-(4-(2-(isopropylsulfonyl)phenylamino)-1H-pyrrolo[2,3-b]pyridin-6-ylamino)-3-methoxyphenyl)piperidin-4-ol, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Dual specificity protein kinase TTK 著者 Filippakopoulos, P, Soundararajan, M, Choi, H, Keates, T, Elkins, J.M, King, O, Fedorov, O, Picaud, S.S, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Grey, N, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2009-02-27 公開日 2009-03-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Nat.Chem.Biol., 6, 2010
3GGR	Crystal Structure of the Human Rad9-Hus1-Rad1 complex 分子名称: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1 著者 Xu, M, Bai, L, Hang, H.Y, Jiang, T. 登録日 2009-03-02 公開日 2009-06-16 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex J.Biol.Chem., 284, 2009
3G60	Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding 分子名称: (4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a 著者 Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G. 登録日 2009-02-05 公開日 2009-03-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (4.4 Å) 主引用文献 Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science, 323, 2009
3DLZ	Crystal structure of human haspin in complex with AMP 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... 著者 Filippakopoulos, P, Eswaran, J, Keates, T, Burgess-Brown, N, Murray, J.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Wickstroem, M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2008-06-30 公開日 2008-07-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure and functional characterization of the atypical human kinase haspin. Proc.Natl.Acad.Sci.USA, 106, 2009
3DYL	human phosphdiesterase 9 substrate complex (ES complex) 分子名称: 3-ISOBUTYL-1-METHYLXANTHINE, CYCLIC GUANOSINE MONOPHOSPHATE, FORMIC ACID, ... 著者 Liu, S, Mansour, M.N, Dillman, K, Perez, J, Danley, D, Menniti, F. 登録日 2008-07-28 公開日 2008-09-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for the catalytic mechanism of human phosphodiesterase 9. Proc.Natl.Acad.Sci.Usa, 105, 2008

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