6WLH
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7MWY
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7MWZ
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7MLM
| Crystal structure of mouse TLR4/MD-2 in complex with sulfatides | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Su, L, Beutler, B. | 登録日 | 2021-04-28 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | Sulfatides are endogenous ligands for the TLR4-MD-2 complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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6WBX
| Single-Particle Cryo-EM Structure of Arabinofuranosyltransferase AftD from Mycobacteria, Mutant R1389S Class 1 | 分子名称: | CALCIUM ION, DUF3367 domain-containing protein | 著者 | Tan, Y.Z, Zhang, L, Rodrigues, J, Zheng, R.B, Giacometti, S.I, Rosario, A.L, Kloss, B, Dandey, V.P, Wei, H, Brunton, R, Raczkowski, A.M, Athayde, D, Catalao, M.J, Pimentel, M, Clarke, O.B, Lowary, T.L, Archer, M, Niederweis, M, Potter, C.S, Carragher, B, Mancia, F. | 登録日 | 2020-03-27 | 公開日 | 2020-05-13 | 最終更新日 | 2020-06-03 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria. Mol.Cell, 78, 2020
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6WBY
| Single-Particle Cryo-EM Structure of Arabinofuranosyltransferase AftD from Mycobacteria, Mutant R1389S Class 2 | 分子名称: | CALCIUM ION, DUF3367 domain-containing protein | 著者 | Tan, Y.Z, Zhang, L, Rodrigues, J, Zheng, R.B, Giacometti, S.I, Rosario, A.L, Kloss, B, Dandey, V.P, Wei, H, Brunton, R, Raczkowski, A.M, Athayde, D, Catalao, M.J, Pimentel, M, Clarke, O.B, Lowary, T.L, Archer, M, Niederweis, M, Potter, C.S, Carragher, B, Mancia, F. | 登録日 | 2020-03-27 | 公開日 | 2020-05-13 | 最終更新日 | 2020-06-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria. Mol.Cell, 78, 2020
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7UIB
| Crystal structure of BoNT/E receptor binding domain in complex with SV2, VHH, and sialic acid | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-beta-neuraminic acid, ... | 著者 | Liu, Z, Jin, R, Chen, P. | 登録日 | 2022-03-29 | 公開日 | 2023-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2. Nat Commun, 14, 2023
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7UIA
| Crystal structure of BoNT/E receptor binding domain in complex with SV2 and VHH | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | 著者 | Liu, Z, Jin, R, Chen, P. | 登録日 | 2022-03-28 | 公開日 | 2023-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2. Nat Commun, 14, 2023
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7UIE
| Crystal structure of HcE-JLE-G6 | 分子名称: | Botulinum neurotoxin E heavy chain, JLE-G6 | 著者 | Jin, R, Lam, K. | 登録日 | 2022-03-29 | 公開日 | 2023-04-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | 主引用文献 | Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2. Nat Commun, 14, 2023
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7EZT
| The structure and functional mechanism of nucleotide regulated acetylhexosaminidase Am2136 from Akkermansia muciniphila | 分子名称: | Beta-N-acetylhexosaminidase, MAGNESIUM ION | 著者 | Bao, R, Li, C.C, Tang, X.Y, Zhu, Y.B, Song, Y.J, Zhao, N.L, Huang, Q, Mou, X.Y, Luo, G.H, Liu, T.G. | 登録日 | 2021-06-02 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Nucleotide binding as an allosteric regulatory mechanism for Akkermansia muciniphila beta- N -acetylhexosaminidase Am2136. Gut Microbes, 14, 2022
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7NKT
| RBD domain of SARS-CoV2 in complex with neutralizing nanobody NM1226 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | 著者 | Ostertag, E, Zocher, G, Stehle, T. | 登録日 | 2021-02-18 | 公開日 | 2021-05-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | NeutrobodyPlex-monitoring SARS-CoV-2 neutralizing immune responses using nanobodies. Embo Rep., 22, 2021
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8SAH
| Huntingtin C-HEAT domain in complex with HAP40 | 分子名称: | 40-kDa huntingtin-associated protein, Huntingtin | 著者 | Harding, R.J, Deme, J.C, Alteen, M.G, Arrowsmith, C.H, Lea, S.M, Structural Genomics Consortium (SGC) | 登録日 | 2023-03-31 | 公開日 | 2023-04-26 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40. Structure, 31, 2023
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5J6D
| Discovery of acyl guanidine tryptophan hydroxylase-1 inhibitors | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-[(N-{[2-(3-methoxyphenoxy)-6-(piperidin-1-yl)phenyl]methyl}carbamimidoyl)carbamoyl]-L-phenylalanine, FE (III) ION, ... | 著者 | Stein, A.J, Goldberg, D.R, De Lombaert, S. | 登録日 | 2016-04-04 | 公開日 | 2016-05-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of acyl guanidine tryptophan hydroxylase-1 inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
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6PXJ
| Crystal structure of human thrombin mutant I16T | 分子名称: | GLYCEROL, MAGNESIUM ION, Thrombin heavy chain, ... | 著者 | Stojanovski, B, Chen, Z, Koester, S.K, Pelc, L.A, Di Cera, E. | 登録日 | 2019-07-26 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Role of the I16-D194 ionic interaction in the trypsin fold. Sci Rep, 9, 2019
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6PXQ
| Crystal structure of human thrombin mutant D194A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombin heavy chain, Thrombin light chain | 著者 | Stojanovski, B, Chen, Z, Koester, S.K, Pelc, L.A, Di Cera, E. | 登録日 | 2019-07-26 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Role of the I16-D194 ionic interaction in the trypsin fold. Sci Rep, 9, 2019
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6PWB
| Rigid body fitting of flagellin FlaB, and flagellar coiling proteins, FcpA and FcpB, into a 10 Angstrom structure of the asymmetric flagellar filament purified from Leptospira biflexa Patoc WT cells resolved via subtomogram averaging | 分子名称: | Flagellar coiling protein A (FcpA), Flagellar coiling protein B (FcpB), Flagellin B1 (FlaB1) | 著者 | Gibson, K.H, Sindelar, C.V, Trajtenberg, F, Buschiazzo, A, San Martin, F, Mechaly, A. | 登録日 | 2019-07-22 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (9.83 Å) | 主引用文献 | An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete. Elife, 9, 2020
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8UNG
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6QZU
| Getah virus macro domain | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Non-structural polyprotein | 著者 | Ferreira Ramos, A.S, Sulzenbacher, G, Coutard, B. | 登録日 | 2019-03-12 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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6R0G
| Getah virus macro domain in complex with ADPr, pose 2 | 分子名称: | ACETATE ION, ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural polyprotein | 著者 | Sulzenbacher, G, Ferreira Ramos, A.S, Coutard, B. | 登録日 | 2019-03-12 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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6R0P
| Getah virus macro domain in complex with ADPr in double open conformation | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Non-structural polyprotein, ... | 著者 | Sulzenbacher, G, Ferreira Ramos, A.S, Coutard, B. | 登録日 | 2019-03-13 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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6R0F
| Getah virus macro domain in complex with ADPr, pose 1 | 分子名称: | Non-structural polyprotein, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | 著者 | Sulzenbacher, G, Ferreira Ramos, A.S, Coutard, B. | 登録日 | 2019-03-12 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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6R0T
| Getah virus macro domain in complex with ADPr in open conformation | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Non-structural polyprotein, ... | 著者 | Ferreira Ramos, A.S, Sulzenbacher, G, Coutard, B. | 登録日 | 2019-03-13 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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6R0R
| Getah virus macro domain in complex with ADPr covalently bond to Cys34 | 分子名称: | 1,2-ETHANEDIOL, Non-structural polyprotein, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-2,3,4,5-tetrakis(oxidanyl)pentyl] hydrogen phosphate | 著者 | Ferreira Ramos, A.S, Sulzenbacher, G, Coutard, B. | 登録日 | 2019-03-13 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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1BZ7
| FAB FRAGMENT FROM MURINE ASCITES | 分子名称: | PROTEIN (ANTIBODY R24 (HEAVY CHAIN)), PROTEIN (ANTIBODY R24 (LIGHT CHAIN)) | 著者 | Kaminski, M.J, Mackenzie, C.R, Mooibroek, M.J, Dahms, T.E.S, Hirama, T, Houghton, A.N, Chapman, P.B, Evans, S.V. | 登録日 | 1998-11-06 | 公開日 | 1999-11-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The role of homophilic binding in anti-tumor antibody R24 recognition of molecular surfaces. Demonstration of an intermolecular beta-sheet interaction between vh domains. J.Biol.Chem., 274, 1999
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1BU8
| RAT PANCREATIC LIPASE RELATED PROTEIN 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (PANCREATIC LIPASE RELATED PROTEIN 2) | 著者 | Roussel, A, Cambillau, C. | 登録日 | 1998-09-14 | 公開日 | 1998-12-23 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and activity of rat pancreatic lipase-related protein 2. J.Biol.Chem., 273, 1998
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