7EZT

The structure and functional mechanism of nucleotide regulated acetylhexosaminidase Am2136 from Akkermansia muciniphila

Summary for 7EZT

Entry DOI	10.2210/pdb7ezt/pdb
Descriptor	Beta-N-acetylhexosaminidase, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	akkermansia muciniphila glycosidase mucin, hydrolase
Biological source	Akkermansia muciniphila (strain ATCC BAA-835 / Muc) More
Total number of polymer chains	4
Total formula weight	329090.40
Authors	Bao, R.,Li, C.C.,Tang, X.Y.,Zhu, Y.B.,Song, Y.J.,Zhao, N.L.,Huang, Q.,Mou, X.Y.,Luo, G.H.,Liu, T.G. (deposition date: 2021-06-02, release date: 2022-11-02, Last modification date: 2023-11-29)
Primary citation	Li, C.C.,Yi, H.,Wang, Y.M.,Tang, X.Y.,Zhu, Y.B.,Song, Y.J.,Zhao, N.L.,Huang, Q.,Mou, X.Y.,Luo, G.H.,Liu, T.G.,Yang, G.L.,Zeng, Y.J.,Wang, L.J.,Tang, H.,Fan, G.,Bao, R. Nucleotide binding as an allosteric regulatory mechanism for Akkermansia muciniphila beta- N -acetylhexosaminidase Am2136. Gut Microbes, 14:2143221-2143221, 2022 Cited by PubMed: 36394293 DOI: 10.1080/19490976.2022.2143221 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.81 Å)

Structure validation