7MLM
Crystal structure of mouse TLR4/MD-2 in complex with sulfatides
Summary for 7MLM
| Entry DOI | 10.2210/pdb7mlm/pdb |
| Descriptor | Toll-like receptor 4,Variable lymphocyte receptor B, Lymphocyte antigen 96, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
| Functional Keywords | innate immunity, endogenous ligands, toll-like receptors, immune system |
| Biological source | Mus musculus (Mouse) More |
| Total number of polymer chains | 2 |
| Total formula weight | 97231.32 |
| Authors | Su, L.,Beutler, B. (deposition date: 2021-04-28, release date: 2021-07-28, Last modification date: 2023-10-18) |
| Primary citation | Su, L.,Athamna, M.,Wang, Y.,Wang, J.,Freudenberg, M.,Yue, T.,Wang, J.,Moresco, E.M.Y.,He, H.,Zor, T.,Beutler, B. Sulfatides are endogenous ligands for the TLR4-MD-2 complex. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 34290146DOI: 10.1073/pnas.2105316118 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.104 Å) |
Structure validation
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