8K3F
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3M2C
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3M2B
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3HZQ
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3BB0
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3HIJ
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![BU of 3hij by Molmil](/molmil-images/mine/3hij) | Crystal structure of dihydrodipicolinate synthase from Bacillus anthracis in complex with its substrate, pyruvate | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL, SODIUM ION | 著者 | Voss, J.E, Scally, S.W, Dobson, R.C.J, Perugini, M.A. | 登録日 | 2009-05-20 | 公開日 | 2009-11-24 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax. J.Biol.Chem., 285, 2010
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3M2A
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3M25
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3M2F
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3M23
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3M2G
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6ES4
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![BU of 6es4 by Molmil](/molmil-images/mine/6es4) | A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Syncrip, ... | 著者 | Hobor, F, Dallmann, A, Ball, N.J, Cicchini, C, Battistelli, C, Ogrodowicz, R.W, Christodoulou, E, Martin, S.R, Castello, A, Tripodi, M, Taylor, I.A, Ramos, A. | 登録日 | 2017-10-19 | 公開日 | 2018-03-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets. Nat Commun, 9, 2018
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5HGJ
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![BU of 5hgj by Molmil](/molmil-images/mine/5hgj) | Structure of integrin alpha1beta1 and alpha2beta1 I-domains explain differential calcium-mediated ligand recognition | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Brown, K.L, Banerjee, S, Feigley, A, Abe, H, Blackwell, T, Zent, R, Pozzi, A, Hudson, B.H. | 登録日 | 2016-01-08 | 公開日 | 2017-04-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | 主引用文献 | Salt-bridge modulates differential calcium-mediated ligand binding to integrin alpha 1- and alpha 2-I domains. Sci Rep, 8, 2018
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1DIE
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![BU of 1die by Molmil](/molmil-images/mine/1die) | OBSERVATIONS OF REACTION INTERMEDIATES AND THE MECHANISM OF ALDOSE-KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE | 分子名称: | 1-DEOXYNOJIRIMYCIN, D-XYLOSE ISOMERASE, MAGNESIUM ION | 著者 | Collyer, C.A, Viehmann, H, Goldberg, J.D, Blow, D.M. | 登録日 | 1992-06-04 | 公開日 | 1993-07-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Observations of reaction intermediates and the mechanism of aldose-ketose interconversion by D-xylose isomerase. Proc.Natl.Acad.Sci.USA, 87, 1990
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1DID
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![BU of 1did by Molmil](/molmil-images/mine/1did) | OBSERVATIONS OF REACTION INTERMEDIATES AND THE MECHANISM OF ALDOSE-KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE | 分子名称: | 2,5-DIDEOXY-2,5-IMINO-D-GLUCITOL, D-XYLOSE ISOMERASE, MANGANESE (II) ION | 著者 | Collyer, C.A, Goldberg, J.D, Blow, D.M. | 登録日 | 1992-06-04 | 公開日 | 1993-07-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Observations of reaction intermediates and the mechanism of aldose-ketose interconversion by D-xylose isomerase. Proc.Natl.Acad.Sci.USA, 87, 1990
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6E2P
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4UOV
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![BU of 4uov by Molmil](/molmil-images/mine/4uov) | The structure of a tetrameric alpha-carbonic anhydrase from Thermovibrio ammonificans reveals a core formed around intermolecular disulfides, which contribute to its thermostability. | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ... | 著者 | James, P, Isupov, M, Sayer, C, Berg, S, Lioliou, M, Kotlar, H, Littlechild, J. | 登録日 | 2014-06-10 | 公開日 | 2014-10-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The Structure of a Tetrameric [Alpha]-Carbonic Anhydrase from Thermovibrio Ammonificans Reveals a Core Formed Around Intermolecular Disulfides that Contribute to its Thermostability Acta Crystallogr.,Sect.D, 70, 2014
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7A9G
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![BU of 7a9g by Molmil](/molmil-images/mine/7a9g) | Truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Mycobacterium tuberculosis with intermediate 2-acetyl-thiamine diphosphate | 分子名称: | 1-deoxy-D-xylulose-5-phosphate synthase,1-deoxy-D-xylulose-5-phosphate synthase, 2-ACETYL-THIAMINE DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Gierse, R.M, Reddem, E, Grooves, M.R. | 登録日 | 2020-09-02 | 公開日 | 2022-03-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | First crystal structures of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization. Sci Rep, 12, 2022
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7QO8
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6V2E
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6F4Z
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3UXL
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3OFS
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![BU of 3ofs by Molmil](/molmil-images/mine/3ofs) | Dynamic conformations of the CD38-mediated NAD cyclization captured using multi-copy crystallography | 分子名称: | ADP-ribosyl cyclase 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4R)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate | 著者 | Zhang, H, Lee, H.C, Hao, Q. | 登録日 | 2010-08-16 | 公開日 | 2010-12-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Dynamic Conformations of the CD38-Mediated NAD Cyclization Captured in a Single Crystal J.Mol.Biol., 405, 2011
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1NSP
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![BU of 1nsp by Molmil](/molmil-images/mine/1nsp) | MECHANISM OF PHOSPHATE TRANSFER BY NUCLEOSIDE DIPHOSPHATE KINASE: X-RAY STRUCTURES OF A PHOSPHO-HISTIDINE INTERMEDIATE OF THE ENZYMES FROM DROSOPHILA AND DICTYOSTELIUM | 分子名称: | NUCLEOSIDE DIPHOSPHATE KINASE | 著者 | Janin, J, Morera, S, Chiadmi, M, Lebras, G, Lascu, I. | 登録日 | 1995-04-18 | 公開日 | 1995-07-10 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mechanism of phosphate transfer by nucleoside diphosphate kinase: X-ray structures of the phosphohistidine intermediate of the enzymes from Drosophila and Dictyostelium. Biochemistry, 34, 1995
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1XSK
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![BU of 1xsk by Molmil](/molmil-images/mine/1xsk) | Structure of a Family 31 alpha glycosidase glycosyl-enzyme intermediate | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 5(R)-fluoro-beta-D-xylopyranose, Putative family 31 glucosidase yicI, ... | 著者 | Lovering, A.L, Lee, S.S, Kim, Y.W, Withers, S.G, Strynadka, N.C. | 登録日 | 2004-10-19 | 公開日 | 2004-11-10 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mechanistic and Structural Analysis of a Family 31 {alpha}-Glycosidase and Its Glycosyl-enzyme Intermediate J.Biol.Chem., 280, 2005
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