3HIJ
Crystal structure of dihydrodipicolinate synthase from Bacillus anthracis in complex with its substrate, pyruvate
Summary for 3HIJ
Entry DOI | 10.2210/pdb3hij/pdb |
Related | 1XKY 1XL9 |
Descriptor | Dihydrodipicolinate synthase, GLYCEROL, SODIUM ION, ... (4 entities in total) |
Functional Keywords | lyase, tim barrel, pyruvate, tetramer, amino-acid biosynthesis, diaminopimelate biosynthesis, lysine biosynthesis, schiff base |
Biological source | Bacillus anthracis (anthrax,anthrax bacterium) |
Cellular location | Cytoplasm (By similarity): Q81WN7 |
Total number of polymer chains | 4 |
Total formula weight | 125780.33 |
Authors | Voss, J.E.,Scally, S.W.,Dobson, R.C.J.,Perugini, M.A. (deposition date: 2009-05-20, release date: 2009-11-24, Last modification date: 2011-07-13) |
Primary citation | Voss, J.E.,Scally, S.W.,Taylor, N.L.,Atkinson, S.C.,Griffin, M.D.,Hutton, C.A.,Parker, M.W.,Alderton, M.R.,Gerrard, J.A.,Dobson, R.C.,Dogovski, C.,Perugini, M.A. Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax. J.Biol.Chem., 285:5188-5195, 2010 Cited by PubMed: 19948665DOI: 10.1074/jbc.M109.038166 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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