4UOV

The structure of a tetrameric alpha-carbonic anhydrase from Thermovibrio ammonificans reveals a core formed around intermolecular disulfides, which contribute to its thermostability.

Summary for 4UOV

Entry DOI	10.2210/pdb4uov/pdb
Descriptor	CARBONATE DEHYDRATASE, TRIETHYLENE GLYCOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ... (12 entities in total)
Functional Keywords	lyase, carbonic anhydrase, thermophilic, acetazolamide, carbon dioxide capture, thermal stability.
Biological source	THERMOVIBRIO AMMONIFICANS
Total number of polymer chains	6
Total formula weight	174733.73
Authors	James, P.,Isupov, M.,Sayer, C.,Berg, S.,Lioliou, M.,Kotlar, H.,Littlechild, J. (deposition date: 2014-06-10, release date: 2014-10-15, Last modification date: 2024-01-10)
Primary citation	James, P.,Isupov, M.N.,Sayer, C.,Saneei, V.,Berg, S.,Lioliou, M.,Kotlar, H.,Littlechild, J. The Structure of a Tetrameric [Alpha]-Carbonic Anhydrase from Thermovibrio Ammonificans Reveals a Core Formed Around Intermolecular Disulfides that Contribute to its Thermostability Acta Crystallogr.,Sect.D, 70:2607-, 2014 Cited by PubMed: 25286845 DOI: 10.1107/S1399004714016526 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation