Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004089 | molecular_function | carbonate dehydratase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0004089 | molecular_function | carbonate dehydratase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| C | 0004089 | molecular_function | carbonate dehydratase activity |
| C | 0008270 | molecular_function | zinc ion binding |
| D | 0004089 | molecular_function | carbonate dehydratase activity |
| D | 0008270 | molecular_function | zinc ion binding |
| E | 0004089 | molecular_function | carbonate dehydratase activity |
| E | 0008270 | molecular_function | zinc ion binding |
| F | 0004089 | molecular_function | carbonate dehydratase activity |
| F | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 298 |
| Chain | Residue |
| A | HIS112 |
| A | HIS114 |
| A | HIS131 |
| A | AZM299 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE AZM A 299 |
| Chain | Residue |
| A | LEU197 |
| A | THR198 |
| A | THR199 |
| A | TRP208 |
| A | ZN298 |
| A | HOH2293 |
| A | GLN110 |
| A | HIS112 |
| A | HIS114 |
| A | HIS131 |
| A | VAL133 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PE3 A 300 |
| Chain | Residue |
| A | ARG105 |
| A | TLA306 |
| A | HOH2183 |
| C | TYR98 |
| C | ARG105 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE B3P A 301 |
| Chain | Residue |
| A | GLU166 |
| A | GLU167 |
| A | LYS227 |
| A | VAL228 |
| A | HOH2326 |
| A | HOH2353 |
| A | HOH2354 |
| E | TYR28 |
| E | ASP232 |
| E | ASN234 |
| E | PEG313 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | LYS124 |
| A | HIS125 |
| A | TYR126 |
| A | HOH2192 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 303 |
| Chain | Residue |
| A | HIS173 |
| E | HIS173 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 304 |
| Chain | Residue |
| A | GLN110 |
| A | HIS112 |
| A | HOH2143 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 305 |
| Chain | Residue |
| A | GLY95 |
| A | TYR107 |
| A | LYS109 |
| A | LEU135 |
| A | ASP136 |
| A | HOH2186 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE TLA A 306 |
| Chain | Residue |
| A | TYR107 |
| A | LYS137 |
| A | PE3300 |
| A | HOH2179 |
| A | HOH2180 |
| A | HOH2209 |
| A | HOH2357 |
| A | HOH2359 |
| C | TYR107 |
| C | LYS137 |
| C | HOH2154 |
| C | HOH2183 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 307 |
| Chain | Residue |
| A | ASP179 |
| A | PRO180 |
| A | GLU181 |
| A | HOH2119 |
| A | HOH2120 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 298 |
| Chain | Residue |
| B | HIS112 |
| B | HIS114 |
| B | HIS131 |
| B | AZM299 |
| site_id | BC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE AZM B 299 |
| Chain | Residue |
| B | GLN110 |
| B | HIS112 |
| B | HIS114 |
| B | HIS131 |
| B | LEU197 |
| B | THR198 |
| B | THR199 |
| B | TRP208 |
| B | ZN298 |
| B | HOH2291 |
| B | HOH2356 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PE3 B 300 |
| Chain | Residue |
| B | TYR98 |
| B | ARG105 |
| B | TLA306 |
| D | TYR74 |
| D | TYR98 |
| D | ARG105 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 302 |
| Chain | Residue |
| B | LYS124 |
| B | HIS125 |
| B | TYR126 |
| B | HOH2193 |
| B | HOH2198 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 303 |
| Chain | Residue |
| B | HIS173 |
| B | PG5312 |
| F | HIS173 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 304 |
| Chain | Residue |
| B | GLN110 |
| B | HIS112 |
| B | HOH2146 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE B 305 |
| Chain | Residue |
| B | ASP136 |
| B | GLY94 |
| B | GLY95 |
| B | TYR107 |
| B | LYS109 |
| site_id | BC9 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE TLA B 306 |
| Chain | Residue |
| B | TYR107 |
| B | LYS137 |
| B | PE3300 |
| B | HOH2182 |
| B | HOH2183 |
| B | HOH2210 |
| B | HOH2211 |
| B | HOH2359 |
| B | HOH2360 |
| D | TYR107 |
| D | LYS137 |
| D | HOH2115 |
| D | HOH2142 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 308 |
| Chain | Residue |
| B | THR175 |
| B | ALA176 |
| F | ARG162 |
| site_id | CC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG B 310 |
| Chain | Residue |
| B | GLU158 |
| B | LYS159 |
| B | ARG162 |
| B | ALA176 |
| B | HOH2238 |
| B | HOH2242 |
| B | HOH2246 |
| B | HOH2251 |
| B | HOH2361 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG5 B 312 |
| Chain | Residue |
| B | LYS171 |
| B | CL303 |
| F | LYS171 |
| F | HIS173 |
| F | PGE309 |
| site_id | CC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG B 314 |
| Chain | Residue |
| B | ASN85 |
| B | GLY169 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 298 |
| Chain | Residue |
| C | HIS112 |
| C | HIS114 |
| C | HIS131 |
| C | AZM299 |
| site_id | CC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE AZM C 299 |
| Chain | Residue |
| C | GLN110 |
| C | HIS112 |
| C | HIS114 |
| C | HIS131 |
| C | LEU197 |
| C | THR198 |
| C | THR199 |
| C | TRP208 |
| C | ZN298 |
| C | HOH2242 |
| C | HOH2286 |
| site_id | CC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE B3P C 301 |
| Chain | Residue |
| C | GLU166 |
| C | GLU167 |
| C | LYS227 |
| C | VAL228 |
| C | HOH2212 |
| C | HOH2269 |
| C | HOH2288 |
| D | TYR28 |
| D | PRO34 |
| D | ASP232 |
| D | ASN234 |
| D | HOH2226 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 302 |
| Chain | Residue |
| C | LYS124 |
| C | HIS125 |
| C | TYR126 |
| C | HOH2167 |
| site_id | CC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 303 |
| Chain | Residue |
| C | HIS173 |
| D | HIS173 |
| site_id | DC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 304 |
| Chain | Residue |
| C | GLN110 |
| C | HIS112 |
| C | HOH2123 |
| site_id | DC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PGE C 305 |
| Chain | Residue |
| C | GLY94 |
| C | GLY95 |
| C | TYR107 |
| C | LYS109 |
| C | ASP136 |
| C | HOH2160 |
| C | HOH2161 |
| site_id | DC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG C 314 |
| Chain | Residue |
| C | ASN85 |
| C | HOH2291 |
| site_id | DC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 298 |
| Chain | Residue |
| D | HIS112 |
| D | HIS114 |
| D | HIS131 |
| D | AZM299 |
| site_id | DC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE AZM D 299 |
| Chain | Residue |
| D | GLN110 |
| D | HIS112 |
| D | HIS114 |
| D | HIS131 |
| D | LEU197 |
| D | THR198 |
| D | THR199 |
| D | TRP208 |
| D | ZN298 |
| site_id | DC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE B3P D 301 |
| Chain | Residue |
| C | TYR28 |
| C | ASP232 |
| C | ASN234 |
| C | HOH2272 |
| D | GLU166 |
| D | GLU167 |
| D | LYS227 |
| D | VAL228 |
| D | HOH2224 |
| D | HOH2240 |
| D | HOH2241 |
| site_id | DC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 302 |
| Chain | Residue |
| D | HIS125 |
| D | TYR126 |
| D | HOH2124 |
| site_id | DC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 304 |
| Chain | Residue |
| D | GLN110 |
| D | HIS112 |
| D | HOH2090 |
| site_id | DC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGE D 305 |
| Chain | Residue |
| D | GLY94 |
| D | GLY95 |
| D | TYR107 |
| D | LYS109 |
| D | LEU135 |
| D | ASP136 |
| site_id | EC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL D 307 |
| site_id | EC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN E 298 |
| Chain | Residue |
| E | HIS112 |
| E | HIS114 |
| E | HIS131 |
| E | AZM299 |
| site_id | EC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AZM E 299 |
| Chain | Residue |
| E | GLN110 |
| E | HIS112 |
| E | HIS114 |
| E | HIS131 |
| E | LEU197 |
| E | THR198 |
| E | THR199 |
| E | TRP208 |
| E | ZN298 |
| E | HOH2332 |
| site_id | EC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE B3P E 301 |
| Chain | Residue |
| A | TYR28 |
| A | ASP232 |
| A | ASN234 |
| A | HOH2328 |
| A | HOH2329 |
| E | GLU166 |
| E | GLU167 |
| E | LYS227 |
| E | VAL228 |
| E | HOH2302 |
| E | HOH2305 |
| E | HOH2335 |
| E | HOH2336 |
| site_id | EC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 E 302 |
| Chain | Residue |
| E | LYS124 |
| E | HIS125 |
| E | TYR126 |
| E | HOH2175 |
| site_id | EC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL E 304 |
| Chain | Residue |
| E | GLN110 |
| E | HIS112 |
| E | HOH2125 |
| site_id | EC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PGE E 305 |
| Chain | Residue |
| E | GLY94 |
| E | GLY95 |
| E | LYS109 |
| E | ASP136 |
| site_id | EC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL E 307 |
| Chain | Residue |
| E | PRO180 |
| E | GLU181 |
| site_id | EC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG E 313 |
| Chain | Residue |
| A | LYS227 |
| A | B3P301 |
| A | HOH2322 |
| A | HOH2352 |
| E | PRO116 |
| site_id | FC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG E 314 |
| Chain | Residue |
| E | VAL83 |
| E | ASN85 |
| E | GLY169 |
| E | HOH2124 |
| site_id | FC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN F 298 |
| Chain | Residue |
| F | HIS112 |
| F | HIS114 |
| F | HIS131 |
| F | AZM299 |
| site_id | FC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AZM F 299 |
| Chain | Residue |
| F | GLN110 |
| F | HIS112 |
| F | HIS114 |
| F | HIS131 |
| F | LEU197 |
| F | THR198 |
| F | THR199 |
| F | TRP208 |
| F | ZN298 |
| F | HOH2270 |
| site_id | FC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PE3 F 300 |
| Chain | Residue |
| E | TYR98 |
| E | ARG105 |
| F | TYR98 |
| F | ARG105 |
| F | TLA306 |
| site_id | FC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE B3P F 301 |
| Chain | Residue |
| B | TYR28 |
| B | ASP232 |
| B | ASN234 |
| B | HOH2332 |
| F | GLU166 |
| F | GLU167 |
| F | LYS227 |
| F | VAL228 |
| F | HOH2294 |
| F | HOH2298 |
| F | HOH2315 |
| F | HOH2317 |
| site_id | FC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 F 302 |
| Chain | Residue |
| F | HIS125 |
| F | TYR126 |
| F | HOH2176 |
| F | HOH2182 |
| F | HOH2184 |
| site_id | FC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL F 304 |
| Chain | Residue |
| F | GLN110 |
| F | HIS112 |
| F | HOH2125 |
| site_id | FC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE TLA F 306 |
| Chain | Residue |
| E | TYR107 |
| E | LYS137 |
| E | HOH2163 |
| E | HOH2164 |
| E | HOH2189 |
| F | TYR107 |
| F | LYS137 |
| F | PE3300 |
| F | HOH2162 |
| F | HOH2163 |
| F | HOH2195 |
| F | HOH2319 |
| site_id | FC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL F 308 |
| Chain | Residue |
| B | ARG162 |
| F | THR175 |
| F | ALA176 |
| F | HOH2230 |
| site_id | GC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE F 309 |
| Chain | Residue |
| B | PG5312 |
| F | LYS80 |
| F | TYR81 |
| F | MET93 |
| F | GLY94 |
| site_id | GC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG F 310 |
| Chain | Residue |
| F | GLU158 |
| F | LYS159 |
| F | ARG162 |
| F | HOH2120 |
| F | HOH2230 |
| F | HOH2320 |
| site_id | GC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG F 314 |
| Chain | Residue |
| F | VAL83 |
| F | ASN85 |
| F | GLY169 |
Functional Information from PROSITE/UniProt
| site_id | PS00162 |
| Number of Residues | 17 |
| Details | ALPHA_CA_1 Alpha-carbonic anhydrases signature. SEHtVngkhYpfEAHFV |
| Chain | Residue | Details |
| A | SER117-VAL133 | |
