7A9G
Truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Mycobacterium tuberculosis with intermediate 2-acetyl-thiamine diphosphate
This is a non-PDB format compatible entry.
Summary for 7A9G
Entry DOI | 10.2210/pdb7a9g/pdb |
Related | 7A9H |
Descriptor | 1-deoxy-D-xylulose-5-phosphate synthase,1-deoxy-D-xylulose-5-phosphate synthase, 2-ACETYL-THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (9 entities in total) |
Functional Keywords | transferase |
Biological source | Mycobacterium tuberculosis H37Rv More |
Total number of polymer chains | 2 |
Total formula weight | 145389.98 |
Authors | Gierse, R.M.,Reddem, E.,Grooves, M.R. (deposition date: 2020-09-02, release date: 2022-03-23, Last modification date: 2024-01-31) |
Primary citation | Gierse, R.M.,Oerlemans, R.,Reddem, E.R.,Gawriljuk, V.O.,Alhayek, A.,Baitinger, D.,Jakobi, H.,Laber, B.,Lange, G.,Hirsch, A.K.H.,Groves, M.R. First crystal structures of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization. Sci Rep, 12:7221-7221, 2022 Cited by PubMed: 35508530DOI: 10.1038/s41598-022-11205-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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