7A9G
Truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Mycobacterium tuberculosis with intermediate 2-acetyl-thiamine diphosphate
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, BBB) | 1-deoxy-D-xylulose-5-phosphate synthase,1-deoxy-D-xylulose-5-phosphate synthase | polymer | 666 | 70987.5 | 2 | UniProt (P9WNS3) Pfam (PF13292) Pfam (PF02779) Pfam (PF02780) | Mycobacterium tuberculosis H37Rv | 1-deoxyxylulose-5-phosphate synthase,DXPS,1-deoxyxylulose-5-phosphate synthase,DXPS |
| 2 | C, O (AAA, BBB) | 2-ACETYL-THIAMINE DIPHOSPHATE | non-polymer | 467.4 | 2 | Chemie (HTL) | |||
| 3 | D, P (AAA, BBB) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, F, G, H, J... (AAA, BBB) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 9 | Chemie (PEG) | |||
| 5 | I, K, L, R, W... (AAA, BBB) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 6 | Chemie (PGE) | |||
| 6 | M, T (AAA, BBB) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 7 | N (AAA) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | Q (BBB) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 9 | AA, Z (BBB, AAA) | water | water | 18.0 | 400 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 29 - 204 (UniProt: P9WNS3)
AAA, BBB: 225 - 628 (UniProt: P9WNS3)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Lys 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Met 10 | - | expression tag |
| Ser 11 | - | expression tag |
| Asp 12 | - | expression tag |
| Tyr 13 | - | expression tag |
| Asp 14 | - | expression tag |
| Ile 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Thr 17 | - | expression tag |
| Thr 18 | - | expression tag |
| Glu 19 | - | expression tag |
| Asn 20 | - | expression tag |
| Leu 21 | - | expression tag |
| Tyr 22 | - | expression tag |
| Phe 23 | - | expression tag |
| Gln 24 | - | expression tag |
| Gly 25 | - | expression tag |
| Ala 26 | - | expression tag |
| Met 27 | - | expression tag |
| Gly 28 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 204 | - | linker |
| Gly 204 | - | linker |
| Gly 204 | - | linker |
| Gly 204 | - | linker |
| Gly 223 | - | linker |
| Gly 224 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 141975.0 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 3414.9 | |
| All* | Total formula weight | 145390.0 |
