7A9G

Truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Mycobacterium tuberculosis with intermediate 2-acetyl-thiamine diphosphate

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	AAA, BBB	1-deoxy-D-xylulose-5-phosphate synthase,1-deoxy-D-xylulose-5-phosphate synthase	polymer	666	70987.5	2	UniProt (P9WNS3) Pfam (PF13292) Pfam (PF02779) Pfam (PF02780) In PDB	Mycobacterium tuberculosis H37Rv	1-deoxyxylulose-5-phosphate synthase,DXPS,1-deoxyxylulose-5-phosphate synthase,DXPS
2	AAA, BBB	2-ACETYL-THIAMINE DIPHOSPHATE	non-polymer		467.4	2	Chemie (HTL)
3	AAA, BBB	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	AAA, BBB	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	9	Chemie (PEG)
5	AAA, BBB	TRIETHYLENE GLYCOL	non-polymer		150.2	6	Chemie (PGE)
6	AAA, BBB	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
7	AAA	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8	BBB	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
9		water	water		18.0	400	Chemie (HOH)

Sequence modifications

AAA, BBB: 29 - 204 (UniProt: P9WNS3)

PDB	External Database	Details
Met 1	-	initiating methionine
Lys 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Pro 9	-	expression tag
Met 10	-	expression tag
Ser 11	-	expression tag
Asp 12	-	expression tag
Tyr 13	-	expression tag
Asp 14	-	expression tag
Ile 15	-	expression tag
Pro 16	-	expression tag
Thr 17	-	expression tag
Thr 18	-	expression tag
Glu 19	-	expression tag
Asn 20	-	expression tag
Leu 21	-	expression tag
Tyr 22	-	expression tag
Phe 23	-	expression tag
Gln 24	-	expression tag
Gly 25	-	expression tag
Ala 26	-	expression tag
Met 27	-	expression tag
Gly 28	-	expression tag

AAA, BBB: 225 - 628 (UniProt: P9WNS3)

PDB	External Database	Details
Gly 204	-	linker
Gly 204	-	linker
Gly 204	-	linker
Gly 204	-	linker
Gly 223	-	linker
Gly 224	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	141975.0
Non-Polymers*	Number of molecules	23
	Total formula weight	3414.9
All*	Total formula weight	145390.0

*Water molecules are not included.