3EKN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ekn by Molmil](/molmil-images/mine/3ekn) | Insulin receptor kinase complexed with an inhibitor | 分子名称: | 2-fluoro-6-{[2-({2-methoxy-4-[4-(1-methylethyl)piperazin-1-yl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide, Insulin receptor | 著者 | Chamberlain, S, Atkins, C, Deanda, F, Dumble, M, Gerding, R, Groy, A, Korenchuk, S, Kumar, R, Lei, H, Mook, R, Moorthy, G, Redman, A, Rowland, J, Shewchuk, L. | 登録日 | 2008-09-19 | 公開日 | 2008-12-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity. Bioorg.Med.Chem.Lett., 19, 2009
|
|
3ELC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3elc by Molmil](/molmil-images/mine/3elc) | Crystal structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with ligand | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-pyrimidin-2-one, GERANYL DIPHOSPHATE, ... | 著者 | Hunter, W.N, Ramsden, N.L, Ulaganathan, V. | 登録日 | 2008-09-22 | 公開日 | 2009-08-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy J.Med.Chem., 52, 2009
|
|
3E8T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3e8t by Molmil](/molmil-images/mine/3e8t) | Crystal Structure of Epiphyas postvittana Takeout 1 | 分子名称: | Takeout-like protein 1, Ubiquinone-8 | 著者 | Hamiaux, C, Stanley, D, Greenwood, D.R, Baker, E.N, Newcomb, R.D. | 登録日 | 2008-08-20 | 公開日 | 2008-12-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal structure of Epiphyas postvittana takeout 1 with bound ubiquinone supports a role as ligand carriers for takeout proteins in insects J.Biol.Chem., 284, 2009
|
|
3EHR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ehr by Molmil](/molmil-images/mine/3ehr) | Crystal Structure of Human Osteoclast Stimulating Factor | 分子名称: | Osteoclast-stimulating factor 1 | 著者 | Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. | 登録日 | 2008-09-14 | 公開日 | 2009-08-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of human osteoclast stimulating factor Proteins, 75, 2009
|
|
3EIY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eiy by Molmil](/molmil-images/mine/3eiy) | |
3ERF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3erf by Molmil](/molmil-images/mine/3erf) | Crystal structure of Gtt2 from Saccharomyces cerevisiae | 分子名称: | Glutathione S-transferase 2 | 著者 | Ma, X.X, Jiang, Y.L, He, Y.X, Chen, Y.X, Zhou, C.Z. | 登録日 | 2008-10-02 | 公開日 | 2009-10-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Structures of yeast glutathione-S-transferase Gtt2 reveal a new catalytic type of GST family. Embo Rep., 10, 2009
|
|
3E8L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3e8l by Molmil](/molmil-images/mine/3e8l) | The Crystal Structure of the Double-headed Arrowhead Protease Inhibitor A in Complex with Two Trypsins | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | 著者 | Bao, R, Jiang, C.-H, Chi, C.W, Lin, S.X, Chen, Y.X. | 登録日 | 2008-08-20 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | The ternary structure of double-headed arrowhead protease inhibitor API-A complexed with two trypsins reveals a novel reactive site conformation. J.Biol.Chem., 284, 2009
|
|
3EB5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eb5 by Molmil](/molmil-images/mine/3eb5) | Structure of the cIAP2 RING domain | 分子名称: | Baculoviral IAP repeat-containing protein 3, SODIUM ION, ZINC ION | 著者 | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | 登録日 | 2008-08-27 | 公開日 | 2008-09-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment. J.Biol.Chem., 283, 2008
|
|
3EPG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3epg by Molmil](/molmil-images/mine/3epg) | |
3E4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3e4d by Molmil](/molmil-images/mine/3e4d) | Structural and Kinetic Study of an S-Formylglutathione Hydrolase from Agrobacterium tumefaciens | 分子名称: | CHLORIDE ION, Esterase D, MAGNESIUM ION | 著者 | Van Straaten, K.E, Gonzalez, C.F, Valladares, R.B, Xu, X, Savchenko, A.V, Sanders, D.A.R. | 登録日 | 2008-08-11 | 公開日 | 2009-08-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | The structure of a putative S-formylglutathione hydrolase from Agrobacterium tumefaciens Protein Sci., 18, 2009
|
|
3EQY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eqy by Molmil](/molmil-images/mine/3eqy) | |
3EVI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3evi by Molmil](/molmil-images/mine/3evi) | Crystal structure of the thioredoxin-fold domain of human phosducin-like protein 2 | 分子名称: | DI(HYDROXYETHYL)ETHER, Phosducin-like protein 2, SODIUM ION | 著者 | Lou, X, Bao, R, Zhou, C, Chen, Y. | 登録日 | 2008-10-13 | 公開日 | 2009-03-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of the thioredoxin-fold domain of human phosducin-like protein 2 Acta Crystallogr.,Sect.F, 65, 2009
|
|
3EWR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ewr by Molmil](/molmil-images/mine/3ewr) | complex of substrate ADP-ribose with HCoV-229E Nsp3 ADRP domain | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3 | 著者 | Xu, Y, Cong, L, Chen, C, Wei, L, Zhao, Q, Xu, X, Ma, Y, Bartlam, M, Rao, Z. | 登録日 | 2008-10-16 | 公開日 | 2009-01-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Crystal structures of two coronavirus ADP-ribose-1''-monophosphatases and their complexes with ADP-Ribose: a systematic structural analysis of the viral ADRP domain. J.Virol., 83, 2009
|
|
3F8L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f8l by Molmil](/molmil-images/mine/3f8l) | Crystal Structure of the Effector Domain of PhnF from Mycobacterium smegmatis | 分子名称: | GLYCEROL, HTH-type transcriptional repressor phnF, SULFATE ION | 著者 | Busby, J.N, Gebhard, S, Cook, G.M, Baker, E.N, Lott, S.J, Money, V.A. | 登録日 | 2008-11-12 | 公開日 | 2009-11-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of PhnF, a GntR-family transcription regulator in Mycobacterium smegmatis To be Published
|
|
2RK1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rk1 by Molmil](/molmil-images/mine/2rk1) | DHFR R67 Complexed with NADP and dihydrofolate | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, DIHYDROFOLIC ACID, Dihydrofolate reductase type 2, ... | 著者 | Krahn, J.M, London, R.E. | 登録日 | 2007-10-16 | 公開日 | 2008-06-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Crystal structure of a type II dihydrofolate reductase catalytic ternary complex. Biochemistry, 46, 2007
|
|
3EZL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ezl by Molmil](/molmil-images/mine/3ezl) | |
3FMI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fmi by Molmil](/molmil-images/mine/3fmi) | |
2RK2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rk2 by Molmil](/molmil-images/mine/2rk2) | DHFR R-67 complexed with NADP | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, Dihydrofolate reductase type 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Krahn, J.M, London, R.E. | 登録日 | 2007-10-16 | 公開日 | 2008-06-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of a type II dihydrofolate reductase catalytic ternary complex. Biochemistry, 46, 2007
|
|
3EYK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eyk by Molmil](/molmil-images/mine/3eyk) | Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | 分子名称: | 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.J, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2008-10-21 | 公開日 | 2009-01-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion Proc.Natl.Acad.Sci.USA, 105, 2008
|
|
3EZR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ezr by Molmil](/molmil-images/mine/3ezr) | CDK-2 with indazole inhibitor 17 bound at its active site | 分子名称: | 3-methoxy-4-{3-[4-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2 | 著者 | Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X. | 登録日 | 2008-10-23 | 公開日 | 2009-02-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor Bioorg.Med.Chem.Lett., 19, 2009
|
|
3FAN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fan by Molmil](/molmil-images/mine/3fan) | Crystal structure of chymotrypsin-like protease/proteinase (3CLSP/Nsp4) of porcine reproductive and respiratory syndrome virus (PRRSV) | 分子名称: | Non-structural protein, PHOSPHATE ION | 著者 | Gao, F, Peng, H, Tian, X, Lu, G, Liu, Y, Gao, G.F. | 登録日 | 2008-11-17 | 公開日 | 2009-09-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). J.Mol.Biol., 392, 2009
|
|
1UBN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ubn by Molmil](/molmil-images/mine/1ubn) | SELENOSUBTILISIN BPN | 分子名称: | CALCIUM ION, PROTEIN (SELENOSUBTILISIN BPN) | 著者 | McRee, D.E, McTigue, M, Hilvert, D. | 登録日 | 1999-06-02 | 公開日 | 1999-06-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Electric fields in active sites: substrate switching from null to strong fields in thiol- and selenol-subtilisins. Biochemistry, 38, 1999
|
|
3EZN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ezn by Molmil](/molmil-images/mine/3ezn) | |
3F0G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f0g by Molmil](/molmil-images/mine/3f0g) | |
3EZV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ezv by Molmil](/molmil-images/mine/3ezv) | CDK-2 with indazole inhibitor 9 bound at its active site | 分子名称: | 4-{3-[7-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2 | 著者 | Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X. | 登録日 | 2008-10-23 | 公開日 | 2009-02-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor Bioorg.Med.Chem.Lett., 19, 2009
|
|