3EVI

Crystal structure of the thioredoxin-fold domain of human phosducin-like protein 2

Summary for 3EVI

• Entry DOI: 10.2210/pdb3evi/pdb
• Descriptor: Phosducin-like protein 2, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... (4 entities in total)
• Functional Keywords: alpha beta, 3-layer(aba) sandwich, unknown function
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 27271.36

Authors

Lou, X.,Bao, R.,Zhou, C.,Chen, Y. (deposition date: 2008-10-13, release date: 2009-03-03, Last modification date: 2023-11-01)

Primary citation

Lou, X.,Bao, R.,Zhou, C.Z.,Chen, Y.
Structure of the thioredoxin-fold domain of human phosducin-like protein 2
Acta Crystallogr.,Sect.F, 65:67-70, 2009

PubMed Abstract: Human phosducin-like protein 2 (hPDCL2) has been identified as belonging to subgroup II of the phosducin (Pdc) family. The members of this family share an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain. The X-ray crystal structure of the Trx-fold domain of hPDCL2 was solved at 2.70 A resolution and resembled the Trx-fold domain of rat phosducin. Comparative structural analysis revealed the structural basis of their putative functional divergence.

PubMed: 19193988
DOI: 10.1107/S1744309108037342

Experimental method

X-RAY DIFFRACTION (2.7 Å)