3EQY
Crystal structure of human MDMX in complex with a 12-mer peptide inhibitor
Summary for 3EQY
Entry DOI | 10.2210/pdb3eqy/pdb |
Related | 2Z5S 2Z5T 3DAB 3DAC 3EQS |
Descriptor | Mdm4 protein, 12-mer peptide inhibitor, GUANIDINE, ... (5 entities in total) |
Functional Keywords | mdm4, mdmx, mdmx-peptide inhibitor complex, oncoprotein, metal-binding, nucleus, zinc-finger |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: O15151 |
Total number of polymer chains | 4 |
Total formula weight | 22503.72 |
Authors | Pazgier, M.,Lu, W. (deposition date: 2008-10-01, release date: 2009-03-17, Last modification date: 2023-09-06) |
Primary citation | Pazgier, M.,Liu, M.,Zou, G.,Yuan, W.,Li, C.,Li, C.,Li, J.,Monbo, J.,Zella, D.,Tarasov, S.G.,Lu, W. Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX. Proc.Natl.Acad.Sci.USA, 106:4665-4670, 2009 Cited by PubMed: 19255450DOI: 10.1073/pnas.0900947106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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